Abstract. The human menopause is hypothesized to be an adaptive trait that allows post-reproductive females to invest in, and avoid reproductive conflict w

Soil-transmitted helminths (STH) are common in (sub)tropical regions and primarily affect impoverished populations. These parasites reside in the gut, where they interact with both the microbiota a...

Journal of Translational Medicine - The associations between a diet that associated with a healthy gut microbiota and the risk of frailty, as well as mortality in older adults with frailty, remains...

Sepsis is acute organ failure resulting from a dysregulated host response to infection.1 Given the marked patient-level heterogeneity in sepsis onset, clinical course, and recovery, investigators have...

When the coronavirus copies itself, there is a chance its RNA will mutate. But new variants must jump from one host to another, and the more infections there are, the better chance this will happen.

Imidazole propionate produced by gut microbiota is associated with atherosclerosis in mouse models and in humans, and causes the development of atherosclerosis through activation of the imidazoline-1 ...

Analyzing readouts of inflammaging across four cohorts, Franck and colleagues identify strong variation and observe that inflammaging, in its known form, primarily emerges in industrialized—but not no...

Targeting a lower MBP (5th vs. 50th centile) in septic shock showed no significant difference in 28-day mortality. This suggests a lower BP target may be safe, reducing vasoactive drug use and related...

Escherichia coli uses curli fibres, oligomers of the functional amyloid CsgA, as a barrier to protect against the predatory bacteria Bdellovibrio bacteriovorus and Myxococcus xanthus in a mechanism th...

Largest study of its kind explores the ‘Matthew effect’ in research.

Background Sepsis is the result of a dysregulated immune response to infection and is associated with acute organ dysfunction. The syndrome’s complexity is contingent upon the underlying pathology and...

Background Sepsis and septic shock are associated with high mortality and morbidity despite adequate standard care. Vitamin C deficiency is a common, potentially reversible, contributor to morbidity a...

Humans and other animals have evolved adaptations to hypoxia, most famously among high altitude people. Oxygen availability, especially at the tissue level, varies at sea level too. Adaptation to h…

Curtis Huttenhower, professor of computational biology and bioinformatics at the Harvard School of Public Health, will deliver a lecture to the Penn State community in honor of World Microbiome Day. T...

Robert F. Kennedy Jr. announced on Wednesday eight new members of the CDC's independent vaccine advisory committee, some of whom have been critics of shots.

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Rainbow trout with depleted secretory IgM reveal interesting insights into the elusive role of this immunoglobulin in maintaining gut microbiota.

A dangerous new proposal is steamrolling through Congress—and it’s the most significant threat to U.S. climate progress in history.