JN117 @jn117.bsky.social · 24/03/2026Wastewater disconnect from hospitalization? On Feb 14, wastewater analysis showed very high levels of infection in Minnesota, but there was limited impact on hospitalization for COVID-19. The hospitalization had been falling since December 28. Feb 15 showed 2.1 hospitalizations per 100K per week. 111
JN117 @jn117.bsky.social · 16/03/2026Mountain climber with LC "I want to share everything I can with others about my story. If there were a fairy that said "30/100 of the M&Ms in that bag are shit pebbles" I wouldn't have even stuck my hand in the bag. I'm the fairy. Avoid COVID. " 1103
JN117 @jn117.bsky.social · 15/03/2026When it comes to vaccines, the words "safe", "immunity" and "prevent" have caused incredible confusion and sparked endless debates. @kmpanthagani.bsky.social 's recent article does a great job explaining how misunderstandings arise. Recommended! www.youcanknowthings.com/when-work-do...youcanknowthings.comWhen “work” doesn’t workI recently gave a talk on vaccine communication, and the most common feedback I got was appreciation for the section on words that confuse people. I’ve written before how a lot of “misinformation” ca... 154
Reposted by JN117Kristen Panthagani, MD, PhD @kmpanthagani.bsky.social · 02/03/2026RFK uses many of the same rhetorical tricks over and over again. It’s tempting to play whack-a-mole with every rumor, but research shows a better (and less exhausting) method: “prebunking” — or teaching people to recognize the patterns used to sell falsehoods. Today's post does just that 👇🏽 1163
Reposted by JN117Denis - The COVID Info Guy @thecovidinfoguy.bsky.social · 24/02/2026Australia: "Most flu deaths this century were recorded in 2025, ABS finds" Last Year (2025): 🔹COVID-19: ~2,161 deaths 🔹Influenza: ~1,701 deaths 🔹RSV: ~582 deathsabc.net.auMost flu deaths this century were recorded in 2025, ABS findsThere were more deaths associated with influenza last year than any other year this century, according to the Australia Bureau of Statistics. 27037
JN117 @jn117.bsky.social · 03/02/2026Surprisingly comprehensive article on recent research in Nordic countries showing health impacts of COVID-19 on cognitive problems, health care utilization, and rates of depression. www.sciencenorway.no/covid19-long...sciencenorway.noResearchers: Not testing for Covid-19 is creating problemsPeople have become sicker after the pandemic, but without Covid-19 testing it's difficult to understand why. 000
JN117 @jn117.bsky.social · 04/01/2026www.cidara.com Cidara Therapeutics is currently in a Phase 3 trial of a long-acting anti-viral against all strains of influenza. In earlier human testing (n=5,000), the preventive medication was 76% effective with a single 450 mg sub-cutaneous dose.cidara.comTargeted Immunotherapy for Transformative Outcomes - Cidara Therapeutics 021
Reposted by JN117Chise @sailorrooscout.bsky.social · 28/12/2025GOOD NEWS! Researchers have shown Alzheimer’s disease can be REVERSED- not just prevented. Using a potent neuroprotective compound called P7C3-A20, they found RESTORING balance to a central cellular energy molecule (NAD+) not only PREVENTED disease features but REVERSED them, EVEN at late stages. 219114844469
Reposted by JN117Paul Offit @pauloffit.bsky.social · 16/12/2025open.substack.com/pub/pauloffi... What do you do if someone offers you $1 million dollars to debate vaccine safety?open.substack.comDebating Science: No ThanksAnti-vaccine activists RFK Jr., Aaron Siri, and Steve Kirsch have asked that I debate them on vaccine safety. One of them offered me $1 million to do it. Here’s why I declined. 0317
JN117 @jn117.bsky.social · 15/12/2025There is a new HHS web page about Lyme. www.hhs.gov/lyme/index.h...hhs.gov 000
JN117 @jn117.bsky.social · 01/12/2025Is COVID "mild"? In a study of 9,000 people who had COVID in 2024, COVID was so "mild" that 24-26% of people had at least one symptom lasting 84 days (fatigue, shortness of breath/respiratory distress, cough, or smell/taste disorder) that they don't have prior. www.shionogi.com/global/en/ne...shionogi.comNew Clinical Data on the Efficacy of Antiviral Treatments for Post-COVID-19 Condition 000
JN117 @jn117.bsky.social · 30/11/2025Shionogi press release: An observational study found a reduction in incidence of post-COVID condition (PCC) in those who took anti-virals (26% versus 24%). PCC defined as persistence of any of 5 specified symptoms on both days 28 & 84. www.shionogi.com/global/en/ne...shionogi.comNew Clinical Data on the Efficacy of Antiviral Treatments for Post-COVID-19 Condition 100
JN117 @jn117.bsky.social · 19/11/2025A nice summary article on remission/cures of autoimmune disease in these initial small trials. It seems like various ways of depleting B cells are all working. The article mentions teclistamab, which I was not familiar with. www.medpagetoday.com/rheumatology...medpagetoday.comMyeloma Drug Performs Well in Autoimmune DiseasesSafety could be problematic, however 010
JN117 @jn117.bsky.social · 14/11/2025This seems like a significant breakthrough in understanding lupus pathogenesis. It connects EBV infection to the disease. Stanford has licensed the technology to a startup, EBVio Inc, founded by the scientists. med.stanford.edu/news/all-new...med.stanford.eduStanford Medicine scientists tie lupus to a virus nearly all of us carryThe Epstein-Barr virus can convert B cells it’s infected into diabolical overlords that reprogram myriad other immune cells to attack our tissues, Stanford Medicine scientists have found. 030
Reposted by JN117Eric Topol @erictopol.bsky.social · 13/11/2025Our randomized, placebo-controlled trial of tirzepatide (Zepbound) for #LongCovid has already enrolled 500 participants of 1000 planned in less than 2 weeks! longcovid.scripps.edu/locitt-t/longcovid.scripps.eduLoCITT-T - Long COVID Treatment TrialThe Long COVID Treatment Trial-Tirzepatide (LoCITT-T) is investigating the efficacy of repurposing this drug to treat Long COVID. 620351
JN117 @jn117.bsky.social · 12/11/2025October 27, 2027 -- FlowFlex introduced first US-approved RSV+Flu+COVID home test. Product is made in their new San Diego, CA facility. Press release: www.aconlabs.com/acon-laborat... @danielgriffinmdphd.bsky.social 120
Reposted by JN117Billy Hanlon @bhanlon15.bsky.social · 29/10/2025Healio: 'Antivirals reduce long COVID incidence at 90 days in patients with rheumatic diseases' www.healio.com/news/rheumat...healio.comAntivirals reduce long COVID incidence at 90 days in patients with rheumatic diseasesCHICAGO — Patients with autoimmune and rheumatic diseases who received antiviral therapy for COVID-19 demonstrated reduced incidence of long COVID symptoms at 90 days post infection, according t... 0196
JN117 @jn117.bsky.social · 17/10/2025The rate of motor vehicle fatalities has return to pre-pandemic rates. www.nhtsa.gov/press-releas... 020
JN117 @jn117.bsky.social · 14/10/2025Wow. Incidence rate (IR) of POTS (Postural Orthostatic Tachycardia Syndrome) over time. IR was 1.42 per 1 million person-years before COVID and 20.3 cases per 1 million person-years after COVID began. 010
JN117 @jn117.bsky.social · 13/10/2025I think this might be the first head-to-head trial of Paxlovid versus Xocova (Ensitrelvir). Seems randomized but open-label. They find faster viral clearance with Paxlovid. Similar viral rebound rates (7% versus 5%). www.thelancet.com/journals/lan... 010
JN117 @jn117.bsky.social · 12/10/2025Health-related absences from work are still elevated compared to pre-pandemic. There is an association between SARS-CoV-2 wastewater levels and absences from work. jamanetwork.com/journals/jam...jamanetwork.comEnduring Outcomes of COVID-19 Work Absences on the US Labor MarketThis cohort study examines the extent to which COVID-19 continues to generate work absences and decrease labor force participation beyond the pandemic period in the US. 030
JN117 @jn117.bsky.social · 11/10/2025President Trump got flu and COVID-19 vaccines today. x.com/kaitlancolli... 000
Reposted by JN117Joel Topf @kidneyboy.bsky.social · 09/10/2025Can’t stop staring at the prevalence of hypertension among young people. www.ahajournals.org/doi/epub/10.... 1135
JN117 @jn117.bsky.social · 06/10/2025Invivyd announces FDA clearance for new Phase 3 clinical trials for intramuscular monoclonals for prevention of COVID. investors.invivyd.com/news-release... 010
JN117 @jn117.bsky.social · 03/10/2025Percent of hospital and ICU beds occupied by RSV, Flu, and COVID patients remains the same as 2 weeks ago, except for COVID, where hospital beds decreased by 0.1%. There is also a new graph of new hospital admissions by virus. www.cdc.gov/nhsn/psc/hos... 010
JN117 @jn117.bsky.social · 02/10/2025CDC seems to think 3x to 4x more Flu illnesses than COVID ? This was the first season CDC attempted to make in-season estimates of disease burden of the "big 3" RSV, Flu, and COVID. RSV and Flu updates went through May, but COVID estimates continued all year. www.cdc.gov/covid/php/su... 010
JN117 @jn117.bsky.social · 30/09/2025Study of vaccine effectiveness against Long COVID finds rates of Long Covid (self-reported symptoms persisting >12 weeks) of ~10-20% after first infection and ~10% of re-infections. pubmed.ncbi.nlm.nih.gov/41021660/ 111
JN117 @jn117.bsky.social · 30/09/2025Deaths involving COVID-19 in preceding 52 weeks Rolling 52-week cumulative deaths dropped below 100,000 for the first time the week of December 21, 2024. 52 weeks preceding 9/20/2025 had 60,891 COVD deaths. Source: National Center for Health Statistics data.cdc.gov/National-Cen... 000
JN117 @jn117.bsky.social · 24/09/2025Science is how we learn new things. Like a treatment for a disease that has never been treatable in all human history. www.bbc.com/news/article...bbc.comHuntington's disease successfully treated for first timeOne of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC. 010
JN117 @jn117.bsky.social · 23/09/2025For the first time in 5 years, COVID-19 is not among the Top 15 leading causes of death. Here is 2024 (whole year) versus 2025 (partial year). This is the CDC wonder query link that will run the Top 15 leading causes of death query with up-to-date provisional data. wonder.cdc.gov/controller/s... 210
JN117 @jn117.bsky.social · 21/09/2025Hospital bed occupancy did not change this week for any of the three monitored illnesses (COVID-19, Influenza, and RSV). A leveling-off/peak is probably occurring. www.cdc.gov/nhsn/psc/hos... 010
JN117 @jn117.bsky.social · 15/09/2025The 2024 BRFSS questionnaire removed questions about COVID & Long COVID. BRFSS is a large (>200K) live telephone survey about health and health conditions. I am not aware of any recurring survey measuring self-reported Long COVID any more. www.cdc.gov/brfss/annual... 121
JN117 @jn117.bsky.social · 15/09/2025Chronic illness can be caused by breathing contaminants in airplane cabin air. (Professor Marr made this a gift link so all can read.) 011
Reposted by JN117Billy Hanlon @bhanlon15.bsky.social · 13/09/2025UAB: “SARS-CoV-2 drives lung foam cell formation linked to long-COVID damage, study finds” “Approximately 15 million to 20 million Americans who have acquired COVID-19 experience persistent symptoms lasting over three months, known as long COVID” www.uab.edu/news/researc...uab.eduSARS-CoV-2 drives lung foam cell formation linked to long-COVID damage, study findsSARS-CoV-2 drives lung foam cell formation linked to long-COVID damage, study finds 02310
JN117 @jn117.bsky.social · 12/09/2025In 2023, there were 770 traffic fatalities in children <=14 years in the USA. crashstats.nhtsa.dot.gov/Api/Public/V... 010
JN117 @jn117.bsky.social · 12/09/2025ICU bed occupancy for COVID increased 0.1% in the last week. Hospital bed occupancy increased 0.2%. This level of COVID hospitalization was last seen March 1, 2025. Flu and RSV were unchanged from previous week. www.cdc.gov/respiratory-... 000
Reposted by JN117Chantzy @chantzy.bsky.social · 11/09/2025Covid has killed ~5-6x the number of people this year as those who died in 9-11. Both are heartbreaking, ❤️🩹 but only one is grieved publicly. The other is barely noticed & declared over 41025249
JN117 @jn117.bsky.social · 05/09/2025If the same thing happened in the USA, I wonder if we would be as quick and efficient as the National Biomedical Research Institute (INRB) of the Democratic Republic of the Congo was in releasing this detailed information about a new ebola spillover. 000
JN117 @jn117.bsky.social · 05/09/2025ICU bed occupancy for COVID increased 0.2% in the last week. Hospital bed occupancy increased 0.1%. Flu and RSV were unchanged from previous week. www.cdc.gov/nhsn/psc/hos... 001
JN117 @jn117.bsky.social · 29/08/2025BLS tracts disability in the workforce overall but also in subpopulations. I think the women with disability graph might show the most devastating increase. Graphs for all populations: fred.stlouisfed.org/tags/series?... 000
JN117 @jn117.bsky.social · 29/08/2025COVID inpatient hospital bed occupancy was up slightly to 0.9%. RSV & Influenza are 0.0% and 0.1%. www.cdc.gov/nhsn/psc/hos... 000
Reposted by JN117Eric Topol @erictopol.bsky.social · 20/08/2025On the marked age differences for susceptibility to Covid, the role of interferon rewiring www.sciencedirect.com/science/arti... 09125
JN117 @jn117.bsky.social · 18/08/2025"The CARTESIAN study makes the case that COVID-19 has aged our arteries, especially for female adults." 000
JN117 @jn117.bsky.social · 16/08/2025ACTIV-6 trial: 14-days of metformin didn't significantly reduce self-reported or doctor-diagnosed risk of Long COVID at 90-, 120-, or 180-days. The 2,983 subjects had outpatient COVID from September 2023 to May 2024. (table reformatted for readability) www.medrxiv.org/content/10.1... 040
JN117 @jn117.bsky.social · 16/08/2025Unfounded Speculation: Sometimes rhinovirus/enterovirus and SARS-CoV-2 have moved in opposite directions. When rhino/entero increases, SARS-CoV-2 decreases, and vice versa. Rhino/entero just started an uptrend. Does that suggest SARS-CoV-2 will peak soon? syndromictrends.com 000
JN117 @jn117.bsky.social · 09/08/2025After reaching a low of 0.4% in June 14 to July 5, the % of hospital beds occupied by patients with COVID-19 has increased to 0.6% on Aug 2. Flu is at 0.1% and RSV at 0.0%. www.cdc.gov/nhsn/psc/hos... 010
JN117 @jn117.bsky.social · 07/08/2025Portable air cleaner lowered blood pressure for those living near highways! 000
Reposted by JN117Billy Hanlon @bhanlon15.bsky.social · 06/08/2025DecodeME: “X marks the spot where ME/CFS biology can be discovered” “DecodeME looked at the DNA of 15,579 people with an ME/CFS diagnosis…the analysis revealed eight genetic ‘signals’ for ME/CFS from the nine million variants studied” #DecodeME www.decodeme.org.uk/x-marks-the-...decodeme.org.ukX marks the spot where ME/CFS biology can be discovered - DecodeME06 August 2025 Scientists, people with ME/CFS, and their charities came together to create DecodeME, the world’s biggest ME/CFS study – and its results are striking. 18,000 people with ME/CFS gave the... 042
Reposted by JN117Paul Offit @pauloffit.bsky.social · 05/08/2025open.substack.com/pub/pauloffi... RFK Jr.'s wants to eliminate vaccines. Here is how he will do it.open.substack.comRFK Jr.’s Plan to Eliminate VaccinesThink VICP 87045
JN117 @jn117.bsky.social · 31/07/2025Small study finds significant benefit to Larazotide in treating MIS-C in children. Although only 12 subjects were enrolled, it was a double-blind, placebo-controlled random trial. 000
