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Juergen Koefinger

@jkoefinger.bsky.social
226 followers 258 following 30 posts

Theory and computation of soft and condensed matter, dead or alive. Currently project leader at MPI of Biophysics in Frankfurt/Germany.

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Juergen Koefinger @jkoefinger.bsky.social · 03/06/2026
I was asked which skills my kids should learn in the age of AI. My answer was critical thinking to protect yourself against being manipulated. Anyhow, critical thinking is only one of the important skills Sarah Connor taught her son John.
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Max Planck Institute of Biophysics @mpibp.bsky.social · 18/05/2026
What does a postdoc do in their “free” time? Spoiler: They don’t have any. But when Marcel Heinz does sneak in a few minutes between tasks, he’s busy building a free, no-registration chemical sketcher—kudos for this valuable contribution to the community! 👉 Check out his project: www.bondcraft.net
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IRB Barcelona @irbbarcelona.org · 04/05/2026
📢 Upcoming Seminar at #IRBBarcelona | Join us for a Research Nodes #seminar this week, with Dr. @sergiocruzleon.bsky.social, from @mpibp.bsky.social. 🤝 Hosted by Dr. Modesto Orozco Register here ➡️ shorturl.at/t7eCl
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Juergen Koefinger @jkoefinger.bsky.social · 20/03/2026
Time to go home! I have reached my thinking limit for today. Wait a second...I misread: I only reached my Thinking Model Limit.
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Juergen Koefinger @jkoefinger.bsky.social · 11/12/2025
Secret Statistical Santa: At the end of the 3-day @imprs-cbp.bsky.social statistics workshop, each student came up with three statistical questions for another student to answer.
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Juergen Koefinger @jkoefinger.bsky.social · 11/12/2025
AI-generated Renaissance-style painting of Adam and Eve holding signs that read 'P-VALUE' to cover their nudity, acting as metaphorical fig leaves.
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Juergen Koefinger @jkoefinger.bsky.social · 05/12/2025
It has started. Gemini Pro used Grokipedia as a source.
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pilarcossio.bsky.social @pilarcossio.bsky.social · 22/10/2025
**Job Alert** Exciting postdoc position available: theoretical and experimental cryo-EM studies of flexible biomolecules. Competitive salary, collaborative environment at NYSBC and Flatiron Institute. Please share!! and contact: pcossio@flatironinstitute.org
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Susana Wadgymar🌿🔬 @smwadgymar.bsky.social · 06/09/2025
"For our scientists" 🧪 By ellecordova on Instagram
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Bussi Lab @bussilab.org · 14/07/2025
📢 New #preprint alert! Our review "RNA Dynamics and Interactions Revealed through Atomistic Simulations" is now available on arxiv.org/abs/2507.08474 ! Written by @bussigio.bsky.social and @ollyfutur.bsky.social
arxiv.org
RNA Dynamics and Interactions Revealed through Atomistic Simulations
RNA function is deeply intertwined with its conformational dynamics. In this review, we survey recent advances in the use of atomistic molecular dynamics simulations to characterize RNA dynamics in di...
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Juergen Koefinger @jkoefinger.bsky.social · 27/06/2025
If you draw from a distribution, but you don’t like the outcome, then it’s a hallucination.
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Juergen Koefinger @jkoefinger.bsky.social · 25/06/2025
Authors of scientific articles are far too often utilizing things, when they are actually just using them.
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Erik Lindahl @eriklindahl.bsky.social · 14/02/2025
If you are interested in postdoctoral research on ligand-gated ion channels and the synapse, or simulation/AI methods for structural biology - drop me a line if you'll be around at Biophysical Society in LA! #bps2025 #bps #biophysics
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Jean-Philip Piquemal @jppiquem.bsky.social · 04/02/2025
New preprint: VTX: Real-time high-performance molecular structure and dynamics visualization software Congrats to all co-authors, especially to the project leads: @maximemaria.bsky.social and @matthieumontes.bsky.social #compchem #compchemsky #biosky #hpc
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Jim Hurley @jimhurley.bsky.social · 09/01/2025
PhDs in biochemistry, structural biology, pharmacology, or similar, located in the US and with strong publication track records and a high motivation to solve Parkinson's, please send CV directly to me at jimhurley@berkeley.edu. Repost appreciated.
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Dr Zoë Ayres @zjayres.bsky.social · 19/12/2024
During my PhD I experienced severe anxiety and depression, along with suicide ideation. Thankfully I got help and I'm still here. As a student I went to find a book mental illness and how to cope during a PhD and didn't find one. That's how "Managing Your Mental Health During Your PhD" came to be.
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Juergen Koefinger @jkoefinger.bsky.social · 19/12/2024
What was a good moment for you in 2024? Here is mine: I had spontaneously decided before the lecture to illustrate Bayes theorem with Nate Silver’s example about the tragic events of 9/11. I did not have the book with me, but the students did a terrific job and the example worked beautifully!
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Giovanni Bussi @bussigio.bsky.social · 10/12/2024
@plumed.org is finally on BlueSky 🦋!!
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Max Bonomi @bonomimax.bsky.social · 06/12/2024
Do you want to work at the interface of molecular simulations, structural biology experiments and #AI? Come to Paris for a PhD at @pasteur.fr 1 PhD position is available in our lab funded by ERC_Research. Please repost!! #compchem #compbio Info 👇 research.pasteur.fr/b/15Hr
research.pasteur.fr
One PhD thesis in integrative structural biology | Research - Institut Pasteur
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Jörg Enderlein @joergenderlein.bsky.social · 30/11/2024
The most diverse group of organisms on the planet are in trouble and the consequences could be dire. www.reuters.com/graphics/GLO...
reuters.com
Insect populations are declining at an unprecedented rate
The most diverse group of organisms on the planet are in trouble and the consequences could be dire.
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Quanta Magazine @quantamagazine.org · 27/06/2024
Proteins do it all. Hemoglobin ferries oxygen around the body. Keratin structures hair, nails and skin. Insulin helps glucose convert into energy. The fold of a protein is critical to its function. Yet no one really knows specifically how protein folding happens. 1/15
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Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 14/06/2024
Join us in Copenhagen 🇩🇰 for a meeting on May 13–15 2025 ☀️ on 💧Biomolecular condensates: From fundamental principles to applications in health and biotech 💧 Lots of amazing speakers and great venue 🍻 events.au.dk/biomolecular... 🧪 🧬 🧶
Flyer for the meeting including a list of speakers
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Stephanie Wankowicz @stephanieaw.bsky.social · 11/05/2024
We were incredibly disappointed with the lack of code or executable accompanying the publication of AF3 in @Nature . This contradicts scientific principles of the ability to evaluate, use, and build upon existing work. zenodo.org/records/1117.... Sign to endorse: docs.google.com/forms/d/e/1F...
zenodo.org
AlphaFold3 Transparency and Reproducibility
Link for endorsement signatures: https://forms.gle/d47w29eGHeL1ejXw9
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Juergen Koefinger @jkoefinger.bsky.social · 27/03/2024
To all Austrians supporting dual-citizinship for Austrian expatriates: Please check out www.beibehaltung.at and consider signing the petition.
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Juergen Koefinger @jkoefinger.bsky.social · 27/03/2024
Why "back calculation" for the calculation of experimental observables from a "forward model", e.g., molecular model. Why not "forward calculation"? Why not "back-calculate" non-observable parameters from experiments? Is there a reference? @lindorfflarsen.bsky.social @carlocamilloni.bsky.social
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Juergen Koefinger @jkoefinger.bsky.social · 27/03/2024
Back then when I did my PhD, a fellow student told me that any typo I find in his printed poster, I can cut out and keep! I guess the same applies to "Encoding prior knowledge in ensemble refinement", which is out now. doi.org/10.1063/5.01...
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Juergen Koefinger @jkoefinger.bsky.social · 27/02/2024
We suggest to use the energy uncertainty in the force field to encode prior knowledge in ensemble refinement of MD. It is determined in the coarse space of observables. See updated doi.org/10.26434/che.... Thanks @carlocamilloni.bsky.social for your feedback!
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Juergen Koefinger @jkoefinger.bsky.social · 01/12/2023
Have you ever wondered how to properly balance information from theory and experiment? If so, check out our preprint. If not, check out our preprint. In any case, please share.
doi.org
Encoding prior knowledge in ensemble refinement
The proper balancing of information from experiment and theory is a long-standing problem in the analysis of noisy and incomplete data. Viewed as a Pareto optimization problem, improved agreement with...
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Juergen Koefinger @jkoefinger.bsky.social · 07/11/2023
I felt so confident that the number of draws is n and not k that I've actually corrected the Wikipedia page en.wikipedia.org/wiki/Hyperge.... Not that I have made the world a better place. But it still feels nice.
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Juergen Koefinger @jkoefinger.bsky.social · 27/10/2023
After work pumpkin carving - Max Planck style
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Juergen Koefinger @jkoefinger.bsky.social · 09/10/2023
My biggest beef with LateX and bibtex are non-sensical error messages.
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Juergen Koefinger @jkoefinger.bsky.social · 04/10/2023
Thanks @chhdellago.bsky.social for the invite! Bluesky looks quite cozy. I guess chances are better than ever that ALL of my (two!) followers will like a post from me.
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