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Dr Jaishree Bhosle

@jia-b.bsky.social
204 followers 270 following 20 posts

Consultant Medical Oncologist, Director of Medical Education and Medical Information Officer. I have opinions which may not be right or well formed.

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Reposted by Dr Jaishree Bhosle
Channel 4 News @channel4news.bsky.social · 03/09/2026
Undercover footage verified by Channel 4 News reveals a secret plot by senior Reform UK figures to break the law on party donations. A leading legal expert is now calling for a criminal investigation. 🔗 Read the exclusive story on Substack:
channel4news.substack.com
Exclusive: Nigel Farage filmed undercover celebrating secret new foreign donations
Undercover footage verified by Channel 4 News reveals a secret plot by senior Reform UK figures to break the law on party donations. A leading legal expert is now calling for a criminal investigation.
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Dr Jaishree Bhosle @jia-b.bsky.social · 23/08/2026
If this hospital's guideline is to call the crash team for an in theatre emergency, than that is a concern. Theatres should have rapid access to skilled staff in an emergency and usually do. If they didn't, that needs some digging into.
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Dr Jaishree Bhosle @jia-b.bsky.social · 23/08/2026
Crash teams are essentially some people who have done ALS. www.resus.org.uk/library/qual....
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Dr Jaishree Bhosle @jia-b.bsky.social · 23/08/2026
Given the culture described in can't see a member of most resus teams interfering with an inprogress resuscitation being run by anaesthetists. Anyone can dial 2222, even receptionist so culture stopped the nurses.
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Dr Jaishree Bhosle @jia-b.bsky.social · 23/08/2026
As a HO I was part of a cardiac resus team, pointless as the last thing they needed was a doctor of 4 months giving an opinion. I was rightly sent away. Still interested to know if any member of the resus team would have been able to influence a bunch on anaesthetists.
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Dr Jaishree Bhosle @jia-b.bsky.social · 23/08/2026
I think the question is what additional skills would have arrived with the crash team? Usually the team is a medical SHO, anaesthetist and ALS trained nurse/outreach. Given they had anaesthetic support and ITU usually attend in theatre emergencies not sure what the medical SHO would add here.
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Reposted by Dr Jaishree Bhosle
Emma Monk @monkemma.bsky.social · 22/08/2026
One of the first "outrageous" claims I saw as Jason Arday's media hounding unfolded was that he ran 30 marathons in 35 days! Wow! What a thing to claim! And the newspapers all suggested there was no evidence he actually did it. Well, they clearly didn't look very hard 🙄 🧵 1/26
Photo after Jason's final marathon taken from his archived blog showing Jason surrounded by supporters in orange charity t-shirts
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Reposted by Dr Jaishree Bhosle
billkittle.bsky.social @billkittle.bsky.social · 12/08/2026
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Marina Purkiss @marina-purkiss.bsky.social · 03/06/2026
Just watch this… And for the love of God, please see Farage for what he is. His response to Sarah Everard Vs his response to Henry Nowak Jaw dropping.
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Reposted by Dr Jaishree Bhosle
Udai Banerji @udaibanerji.bsky.social · 20/04/2026
At ##AACR26 , great to see the Cancer Therapeutics podium filled by ex Drug Development Unit fellows who are now Profs all across the world! @icr.ac.uk @royalmarsden.org . 👏👏👏
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Reposted by Dr Jaishree Bhosle
Mar Hicks @histoftech.bsky.social · 06/02/2026
No joke: I got angry hate mail today for writing an obituary of a Black woman scientist—because the person felt she did didn’t deserve the recognition. Which just makes me want to share it again: www.nature.com/articles/d41...
nature.com
Gladys Mae West obituary: mathematician who pioneered GPS technology
She made key contributions to US cold-war science despite facing huge barriers as a Black woman.
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Dr Jaishree Bhosle @jia-b.bsky.social · 01/01/2026
I've liked this, but truly 5k every day....I'll think of you whilst chilling with a coffee! Jx
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Reposted by Dr Jaishree Bhosle
Otto English @ottoenglish.bsky.social · 06/10/2025
Dear Gods of all that is stupid... IT'S REAL.
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Dr Jaishree Bhosle @jia-b.bsky.social · 09/08/2025
Odd that your bio doesn't say which party you're an MP for. I wondered if it was Reform, but maybe that's your intention. Good to remove illegal migrants, and please fine those businesses creating a pull for them to come, but 'cleaning up' terrible language.
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Dr Jaishree Bhosle @jia-b.bsky.social · 08/08/2025
Trainees or doctors in postgraduate training?
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Reposted by Dr Jaishree Bhosle
Felicity Hannah @felicityhannah.bsky.social · 22/02/2025
The trouble is, once I started imagining they were taking selfies I couldn’t unsee it
Three marble statues all holding their hands up to their faces
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Dr Jaishree Bhosle @jia-b.bsky.social · 14/02/2025
If you want to cheer yourself up this weekend....or maybe not.
theguardian.com
2073 review – Asif Kapadia’s harrowing vision of a post-apocalyptic world
Samantha Morton plays a mute survivor in the near future in a bold blend of sci-fi and nonfiction inspired by Chris Marker’s 1962 film La Jetée
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Dr Jaishree Bhosle @jia-b.bsky.social · 20/12/2024
Had this yesterday. The overground trains didn't have crew or drivers. It was a like a lottery if I would get home or spend £££ on a taxi.
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Reposted by Dr Jaishree Bhosle
BTOG @btog.bsky.social · 11/12/2024
BTOG is delighted to present an on-site professional childcare service at #BTOG25, acknowledging the requirements of our conference delegates who may be accompanied by their young children. Details on the website www.btog.org/23rd-btog-an...
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Dr Jaishree Bhosle @jia-b.bsky.social · 07/12/2024
Congratulations!
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BTOG @btog.bsky.social · 06/12/2024
NEW NICE APPROVAL published today. NICE has appraised durvalumab within its marketing authorisation, as neoadjuvant treatment with platinum-based chemotherapy ... (continued) #LCSM #lungcancer
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Stephen Liu @stephenvliu.bsky.social · 02/12/2024
Final OS results from RELAY (1L erlotinib +/- ramucirumab in #EGFR NSCLC) now @jtoonline.bsky.social. Regimen FDA approved based on PFS benefit. After 45m f/u, no OS difference (51m vs 46m, HR 0.98). Over 80% received 2L therapy (osimertinib use similar in both arms). www.jto.org/article/S155...
jto.org
RELAY: Final Overall Survival for Erlotinib + Ramucirumab or Placebo in Untreated, EGFR-Mutated Metastatic NSCLC
RELAY, a global double-blind, placebo-controlled Phase 3 study (NCT02411448) demonstrated statistically significant improvement in progression-free survival (PFS; primary endpoint) for ramucirumab (RA...
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Dr Jaishree Bhosle @jia-b.bsky.social · 01/12/2024
Finally!
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Jarushka Naidoo @drjnaidoo.bsky.social · 01/12/2024
Pleased to share our paper on the impact of severe irAEs in adv NSCLC #TheOncologist - 3211pts, ConcertAI database - 8.6% s-irAEs: diarrhea 3.5%, pneu 1.4% - s-irAEs req steroids/immunosuppression=53%⬆️risk death v no irAE @oncoalert.bsky.social #MedSky #OncSky #LCSM academic.oup.com/oncolo/advan...
academic.oup.com
Management of severe immune-related adverse events and outcomes in patients with advanced non-small cell lung cancer receiving immune checkpoint inhibitors
AbstractBackground. Immune checkpoint inhibitors (ICIs) are associated with severe immune-related adverse events (s-irAEs) that result in hospitalization,
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Reposted by Dr Jaishree Bhosle
Stephen Liu @stephenvliu.bsky.social · 28/11/2024
Real world outcomes with dabrafenib + trametinib in #BRAF V600E NSCLC in "Lung Cancer" (IFCT-2004 BLaDE, n=163). First-line: RR 83%, PFS 18m, OS 24m. Later line: RR 74%, PFS 10m, OS 20m. D/C for toxicity ~10%. Curious about IO outcomes by smoking history. www.lungcancerjournal.info/article/S016...
lungcancerjournal.info
DEFINE_ME
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Patrick Forde @patrickforde.bsky.social · 26/11/2024
Skyscraper (phase 3 trial of tira plus atezo in PD-L1 high advanced lung cancer) ultimately negative. The rollercoaster is finally back at base, disappointing news and doesn’t bode well for TIGIT as a target. #lcsm www.gene.com/media/press-...
gene.com
Genentech: Press Releases | Monday, Nov 25, 2024
Discover the latest news about our company, our products, our policies, and our people.
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Reposted by Dr Jaishree Bhosle
Stephen Liu @stephenvliu.bsky.social · 26/11/2024
Press release: phase III SKYSCRAPER-01 study negative for OS at final analysis. Adding anti-TIGIT tiragolumab to first line atezolizumab in advanced PDL1 high NSCLC did not improve PFS or OS. Now to dissect what happened between phase II and III. www.gene.com/media/press-...
gene.com
Genentech: Press Releases | Monday, Nov 25, 2024
Discover the latest news about our company, our products, our policies, and our people.
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Reposted by Dr Jaishree Bhosle
Professor Alastair Greystoke @prof-ali-g.bsky.social · 25/11/2024
Presented today at #RCPathGenomics about NHSE cfDNA pilot. Token oncologist in the room. Not sure what @bsky.app version of a tweetorial is. Issues addressed within the pilot can be found at www.roche-images.co.uk/Genomics_Lun...
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Reposted by Dr Jaishree Bhosle
Deborah Meaden @deborahmeaden.bsky.social · 24/11/2024
Don’t be had… Which report in 2021 found 98pc of goods on sale Black Friday were same price at other times of the year. If you genuinely need something make sure you KNOW it’s a good deal and avoid “ Browsing”.. if you don’t know you need you probably don’t!!
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Reposted by Dr Jaishree Bhosle
Stephen Liu @stephenvliu.bsky.social · 23/11/2024
Final survival results from phase II study of lorlatinib in #ALK NSCLC @jtoonline.bsky.social. In treatment naive (n=30), 5y OS 76%. Post 2nd gen ALK TKI ± chemo (n=28), 5y OS 45%, median OS 37.4m. Post ≥2 ALK TKIs ± chemo (n=111), 5y OS 23%, median OS 19.2m. #LCSM www.jto.org/article/S155...
jto.org
Brief Report: Final overall survival and long-term safety of lorlatinib in patients with ALK-positive non-small cell lung cancer from the pivotal phase 2 study
Lorlatinib is a potent, brain-penetrant, third-generation inhibitor of anaplastic lymphoma kinase (ALK) and ROS1 tyrosine kinases with broad coverage of ALK resistance mutations. We present overall su...
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Stephen Liu @stephenvliu.bsky.social · 24/11/2024
Dr. Liza Villaruz at #MaTOS24 discusses #NTRK and NSCLC. Three approved agents: larotrectinib, entrectinib, and now repotrectinib. Effective but note on target toxicities including dizziness, paresthesias, weight gain, pain withdrawal - on target toxicities to watch for. #LCSM #OncSky
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Tatiana Prowell, MD @tmprowell.bsky.social · 12/11/2024
NEW #Oncology: EGFR expression mediates resistance to T-DXd (EGFR overexpression ⬇️ HER2 homodimerization & HER2/ADC internalization) Combining with EGFR mAbs restored HER2/ADC trafficking & ⬆️ activity in nonclinical models #DrugDevelopment #OncoSky www.cell.com/cell-reports...
cell.com
EGFR-directed antibodies promote HER2 ADC internalization and efficacy
Gupta et al. demonstrate that high EGFR expression mediates resistance to HER2 antibody drug conjugates (ADCs) including trastuzumab deruxtecan (T-DXd) by limiting HER2/ADC internalization. The additi...
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Russ Jones @russincheshire.bsky.social · 20/11/2024
Because some damn fool asked, here's a thread about Baxter. This was taken on the day I brought home Baxter and threw away all hope of an easy life. Look at him. Absolutely irresistible. And that's how they get you, the utter bastards
Baxter looking unbearably cute
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Dr Jaishree Bhosle @jia-b.bsky.social · 20/11/2024
@prof-ali-g.bsky.social and @tnewsomdavis.bsky.social
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Dr Jaishree Bhosle @jia-b.bsky.social · 20/11/2024
Me and @drmaryobr.bsky.social
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Being Reese @beingreese.bsky.social · 19/11/2024
Octavia Butler being a time traveler or seer, will forever be a hill I'm willing to die on, because there's just no way. Parable of The Sower was published in 1993. Look at this date. #BlackBookSky #BookSky
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Davidmcmahon @drdavidmcmahon.bsky.social · 20/11/2024
www.lungcancerjournal.info/article/S016... Welcome to #oncsky @dralexiusjohn.bsky.social Celebrate with our paper evaluating the metabolic toxicities of Lorlatinib published in Lungcancer this week
lungcancerjournal.info
DEFINE_ME
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Joel Topf @kidneyboy.bsky.social · 19/11/2024
Honey, stop what you're doing, new hyponatremia research just dropped! What's it say? It looks like slow correction is associated with worse outcomes, like death and length of stay! Was it just a small study? No, it was a meta-analysis of almost 12,000 patients! jamanetwork.com/journals/jam...
jamanetwork.com
Correction Rates and Clinical Outcomes in Hospitalized Adults With Severe Hyponatremia
This systematic review and meta-analysis evaluates the association of sodium correction rates with mortality among hospitalized adults with severe hyponatremia.
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Dr Jaishree Bhosle @jia-b.bsky.social · 18/11/2024
Happy Birthday!
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Martin Scheinin @martinscheinin.bsky.social · 18/11/2024
This is fantastic. One need not adopt all 20 in one go. Among my favourites are items 3 (McMuskism) and 17 (scepticism). www.theguardian.com/commentisfre...
theguardian.com
How to survive the broligarchy: 20 lessons for the post-truth world | Carole Cadwalladr
In the wake of Trump’s unnerving appointees, the investigative journalist and veteran of the libel court offers pointers on coping in an age of surveillance
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Dr Jaishree Bhosle @jia-b.bsky.social · 17/11/2024
I've switched. Does take some getting used to but has helped me remember to put things in that we discussed that are important to the patient but less so to other medical professionals; which I wasn't expecting.
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Dr Jaishree Bhosle @jia-b.bsky.social · 17/11/2024
Grear= great. Needs at edit button.
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Dr Jaishree Bhosle @jia-b.bsky.social · 17/11/2024
Liking this place. Have just purchased two new books based on recommendations and booked a comedy show! Grear to have something that adds value to my life.
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Clive Peedell @drpeedell.bsky.social · 17/11/2024
This single paragraph explanation of the 2008 financial crisis by Prof Mark Blyth cannot be shared enough. It will happen again. Please share
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James O’Brien @mrjamesob.bsky.social · 17/11/2024
Lie-in disturbed by my departure from Twitter being discussed on Radio 4!
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The Francis Crick Institute @crick.ac.uk · 07/10/2024
We're delighted to lead a new project with The Royal Marsden NHS Foundation Trust to study responses to cancer immunotherapy. The platform received £20m+ in public and industry investment and will involve thousands of people from across the UK receiving immunotherapy 🔗 crick.ac.uk/news-and-rep...
crick.ac.uk
Multi-million pound UK-wide platform into cancer immunotherapy launches
A nationwide team of universities, hospitals and industry, led by the Francis Crick Institute and The Royal Marsden NHS Foundation Trust, have launched a new platform to understand immunotherapy respo...
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Dr Jaishree Bhosle @jia-b.bsky.social · 15/11/2024
Hey you're here too.
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Dr Jaishree Bhosle @jia-b.bsky.social · 14/11/2024
Isn't this her? ashleygwinter.bsky.social
ashleygwinter.bsky.social
Ashley Winter MD | Urologist (@ashleygwinter.bsky.social)
Urologist + Sex Med Doc. Chief Medical Officer at Odelahealth.com She/Her.
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