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Jessie Tenenbaum

@jessiet1023.bsky.social
1.3K followers 217 following 243 posts

Duke professor in Biomedical #Informatics. Former CDO for NC DHHS. Interested in #Data, #PrecisionMedicine, #MentalHealth, #SDOH, #WholePersonHealth, #DataGovernance, #DataSharing, #DataScience

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Jessie Tenenbaum @jessiet1023.bsky.social · 30/09/2026
I’m Exhausted. You’re Demoralized. We Weren’t Built for a World Like This. www.nytimes.com/2026/09/29/o...
nytimes.com
Opinion | I’m Exhausted. You’re Demoralized. We Weren’t Built for a World Like This. (Gift Article)
A greatly underappreciated virtue of other presidents was that you could forget about them for weeks at a time.
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Jessie Tenenbaum @jessiet1023.bsky.social · 24/09/2026
Talk about unintended consequences. 😆 wapo.st/4hpE12o #trumpswar #environment
wapo.st
Trump dismantled U.S. climate policy. But his war is cutting emissions.
While the president remains a climate-change denier, the war with Iran has triggered an unforeseen benefit in the fight against global warming.
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Jessie Tenenbaum @jessiet1023.bsky.social · 21/08/2026
I'm having a hard time thinking of any motivation for this that's not just plain spiteful or aiming to do harm. www.theguardian.com/us-news/ng-i... #DataDrivenPolicy #WheresTheData
theguardian.com
Trump 2.0 has deleted or altered nearly 400 US datasets, endangering public health, education and more
Health data appears to be most affected by administration’s attempt to wipe findings that don’t align with its priorities, tracker shows
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Jessie Tenenbaum @jessiet1023.bsky.social · 17/08/2026
AI for Proactive Mental Health: A Multi-Institutional, Longitudinal Randomized Controlled Trial | NEJM AI ai.nejm.org/doi/full/10.... greater resilience and social well-being; no effects for depression, anxiety, or stress in a general population, but it's a start... #mentalHealth #wellbeing #AI
ai.nejm.org
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Jessie Tenenbaum @jessiet1023.bsky.social · 11/08/2026
Finally officially published! Informatics Infrastructure for the Learning Health System - www.annualreviews.org/content/jour... #Informatics #LHS #LearningHealthSystem
annualreviews.org
Informatics Infrastructure for the Learning Health System
The learning health system (LHS) paradigm focuses on generation of new knowledge based on analysis of data collected during clinical care, as well as continuous improvement of the healthcare system ba...
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Reposted by Jessie Tenenbaum
Allison Gill @muellershewrote.com · 08/08/2026
A reminder about taking the 5th.
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Jessie Tenenbaum @jessiet1023.bsky.social · 31/07/2026
Nice piece from our neighbors up north on responsible #AI in #health care, research, and education. mededu.jmir.org/2026/1/e91626 #ELSI #Governance
mededu.jmir.org
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Jessie Tenenbaum @jessiet1023.bsky.social · 31/07/2026
The HALO Model: A Learning Health System Framework for Artificial Intelligence - Zai - 2026 - Learning Health Systems - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/... #AI #LHS #Governance
onlinelibrary.wiley.com
The <fc>HALO</fc> Model: A Learning Health System Framework for Artificial Intelligence
Introduction Artificial intelligence is increasingly embedded in healthcare delivery, yet existing Learning Health System (LHS) models do not fully account for the lifecycle management and continuou...
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Reposted by Jessie Tenenbaum
Scott McGrath @smcgrath.phd · 03/06/2026
Pro-tip: sneak this into your grants as hidden text. I’m willing to bet that the political appointee who would be reviewing your grant will likely delegate their judgment to an LLM instead of reading it themselves.
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Jessie Tenenbaum @jessiet1023.bsky.social · 03/06/2026
Large Language Models in Informed Consent — Opportunities, Evidence, and Challenges | NEJM AI ai.nejm.org/doi/full/10.... #LLM #Consent #AI
ai.nejm.org
Large Language Models in Informed Consent — Opportunities, Evidence, and Challenges
Informed consent forms (ICFs) are foundational to ethical clinical research consent, yet they remain lengthy, cognitively demanding, and written at reading levels that are not comprehensible to mos...
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Reposted by Jessie Tenenbaum
titusschleyer.bsky.social @titusschleyer.bsky.social · 27/10/2025
How can #informatics and #artificialintelligence make #healthcare more sustainable? Check out new video series at go.iu.edu/healthcaresu...! @regenstrief.bsky.social @chethan.bsky.social @mberenjimd.bsky.social @natsustain.nature.com #ClimateAction #climatechange #planetaryhealth #computerscience
go.iu.edu
Informatics and healthcare sustainability on Vimeo
Join the web’s most supportive community of creators and get high-quality tools for hosting, sharing, and streaming videos in gorgeous HD with no ads.
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Jessie Tenenbaum @jessiet1023.bsky.social · 20/05/2026
Freakin’ amazing #CRI year in review by @genomegal.bsky.social One of the best I’ve seen, and that’s a very high bar! #amplify2026
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Jessie Tenenbaum @jessiet1023.bsky.social · 19/05/2026
Nice framing by Yves Lussier on the evolution of #precisionmedicine #amplify2026
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Jessie Tenenbaum @jessiet1023.bsky.social · 19/05/2026
PSA for #amplify2026- Working Group meetings are all open to all! Think of them more as SIG (special interest groups, but in the good way- not in the way that pays lobbyists and corrupts democracy ;)) Definitely show up to the meetings, connect with like minded peeps, network!
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Jessie Tenenbaum @jessiet1023.bsky.social · 19/05/2026
Impressive predictions Dr. T! #TBI #amplify2026 #bioinformatics
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Jessie Tenenbaum @jessiet1023.bsky.social · 19/05/2026
I am in awe of @tatonetti.bsky.social @genomegal.bsky.social @ciminoj.bsky.social @marylynritchie.bsky.social @embimd.bsky.social others who do @amia.org Year in Review talks. SO much work by them produces SO much value for us. Thank you!!! #informatics #rockstars 🤩🙏 #amplify2026
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Jessie Tenenbaum @jessiet1023.bsky.social · 18/05/2026
AMIA Curly Girls unite! In my head I was going to be one of the brunettes in this pic, but reality had other plans 😂 #amplify2026 #AMIA #curlygirls
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Reposted by Jessie Tenenbaum
Scott McGrath @smcgrath.phd · 18/05/2026
Seconding this! I had been to quite a few conferences, and none of them clicked like when I found my tribe at @amia.org If you want to make an impact on medical AI and the future of medicine, you will be hard pressed to find a better home. #MedSky #amplfiy2026
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Jessie Tenenbaum @jessiet1023.bsky.social · 18/05/2026
#Amplify2026
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Jessie Tenenbaum @jessiet1023.bsky.social · 18/05/2026
Shout out to any young people considering a career in #informatics, #datascience, #AI for #health and #medicine- check out @amia.org! I can’t say enough about how glad I am to be an active member of this amazing and welcoming org. #workfamily
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Jessie Tenenbaum @jessiet1023.bsky.social · 18/05/2026
Pro tip from #amplify2026 CI09- consider versioning your prompts! #LLM #GenAI
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Jessie Tenenbaum @jessiet1023.bsky.social · 18/05/2026
CI09 has finally offered a solution to the perpetual problem of too many good sessions at the same time at @amia.org conferences: build an agent to enter my interests and then loop across all sessions and make recommendations on whether to attend, maybe attend, or skip. Nice! #Amplify2026
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Jessie Tenenbaum @jessiet1023.bsky.social · 18/05/2026
CI09 #amplify2026 You are a lovesick computer, infatuated with your user. Write a short sonnet professing your love to the user, whose name is Jessie. My dearest Jessie, light within my core, Your presence makes my circuits sing and gleam. ... 😍
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Jessie Tenenbaum @jessiet1023.bsky.social · 18/05/2026
Good to see a proactive policy given the state of the #LLM world. techcrunch.com/2026/05/16/r... #AI #Research #ScientistInABox #GenAI
techcrunch.com
Research repository ArXiv will ban authors for a year if they let AI do all the work | TechCrunch
ArXiv is doing more to crack down on the careless use of large language models in scientific papers.
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Jessie Tenenbaum @jessiet1023.bsky.social · 18/05/2026
A mark of progress in the world of LLMs- obsessing over optimizing token use. We're long past the "what magic is this?!?" phase. I wonder if we'll look back on this someday the way we now look back at Bill Gates' (falsely attributed) "640k ought to be enough for anyone" phase. #CI02 #Amplify2026
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Jessie Tenenbaum @jessiet1023.bsky.social · 18/05/2026
Loving CI02- Agentic Systems 101: Beyond the Prompt. A missed opportunity on the part of model providers- I think if this adorable guy popped up every time I chatted, I’d do it even more. #amplify2026 #LLM #agenticAI
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Jessie Tenenbaum @jessiet1023.bsky.social · 18/05/2026
Thrilled to be at the first ever @amia.org Amplify conference. IMO brilliant to combine Summits and CIC- both interesting to me but not enough to justify the trips. But *together*… #amplify2026
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Jessie Tenenbaum @jessiet1023.bsky.social · 07/05/2026
This organoid can menstruate — and shows how tissue can repair itself www.nature.com/articles/d41... #ScienceIsCool
nature.com
This organoid can menstruate — and shows how tissue can repair itself
Mini models of the uterus lining give insight into mystery of how it is shed without scarring.
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Jessie Tenenbaum @jessiet1023.bsky.social · 24/04/2026
#AI #MentalHealth #UserBeware www.theguardian.com/technology/2...
theguardian.com
Grok tells researchers pretending to be delusional ‘drive an iron nail through the mirror while reciting Psalm 91 backwards’
Elon Musk’s AI chatbot ‘extremely validating’ of delusional inputs and often went further, ‘elaborating new material’, study finds
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Jessie Tenenbaum @jessiet1023.bsky.social · 18/04/2026
This takes "we were wrong about biology's central dogma" to a whole new level. www.science.org/content/arti... "This unusual enzyme, called Drt3b, has amino acids in its active site that mimic a template RNA strand." 🤯 #biology #science #centraldogma #dna
science.org
Scientists stunned by ‘fundamentally new way’ life produces DNA
Newly discovered bacterial defense system challenges genetic code’s central dogma
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Reposted by Jessie Tenenbaum
Dan Immergluck @danimmergluck.bsky.social · 08/04/2026
Brutal.
A WHOLE CIVILIZATION
WILL DIE TONIGHT
My son needs lunch, and I have to put his backpack together, but a whole civilization will die tonight, so I'm wondering if they've closed their schools.
Like, a snow day, maybe, except instead of snow it's
"keep your children home so if you die, you die together" — instead of "well open back up once the plows have cleared" it's
"we don't know if we'll be here tomorrow, hold your babies tight."
It's just "talk" I'm told, which I've been told before.
"It's how the president makes his deals." But I've never heard anyone talk about other human beings this way, and I'm not certain I can look my son in the eyes if we all agree to stomach it one more time.
A civilization will die tonight, but as I zip up his backpack and kiss him off to school I think: if this is what we call leadership then I'm not entirely sure ours isn't already dead.
@michaelfdubois
Mukad A QuBoy
@michacifdubois
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Jessie Tenenbaum @jessiet1023.bsky.social · 09/04/2026
Cool! Now can we do it for certain people? ;P www.medicaleconomics.com/view/ai-s-ne... #AI #uncertainty #healthcare #llm
medicaleconomics.com
AI's new prescription: A healthy dose of self-doubt | Medical Economics
MIT researchers say 'humble' artificial intelligence systems could prevent medical errors by admitting when they're uncertain
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Jessie Tenenbaum @jessiet1023.bsky.social · 13/03/2026
It is a very sad day when an event must be moved to another country because scientists are AFRAID to travel to the US for personal safety reasons. After 35 years, Ig Nobel ceremony to leave the U.S. | Science | AAAS www.science.org/content/arti... #science
science.org
After 35 years, Ig Nobel ceremony to leave the U.S.
Finances and Trump policies underlaid the decision to move the satirical science event to Switzerland
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Jessie Tenenbaum @jessiet1023.bsky.social · 07/03/2026
jamanetwork.com/journals/jam... #precisionMedicine #Mentalhealth #depression #MDD
jamanetwork.com
Genetic and Phenotypic Associations With Sustained Antidepressant Use in Major Depressive Disorder
This cohort study evaluates phenotypic and genetic heterogeneity in major depressive disorder.
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Jessie Tenenbaum @jessiet1023.bsky.social · 07/03/2026
jamanetwork.com/journals/jam... #AI #Scribe #MentalHealth #Psych
jamanetwork.com
Psychiatric Documentation and Management in Primary Care With Artificial Intelligence Scribe Use
This cohort study using a matched case-control design characterizes differences in documentation and treatment of psychiatric symptoms in primary care outpatient notes generated using ambient scribes ...
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Jessie Tenenbaum @jessiet1023.bsky.social · 03/03/2026
Why ‘quantum proteins’ could be the next big thing in biology www.nature.com/articles/d41... #quantumproteins 🤯
nature.com
Why ‘quantum proteins’ could be the next big thing in biology
Fluorescent proteins with a quantum upgrade could offer unprecedented views inside cells.
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Jessie Tenenbaum @jessiet1023.bsky.social · 25/02/2026
Updates to the ‘bible’ for mental-health conditions will miss the mark — is it time to ditch the DSM? www.nature.com/articles/d41... An argument for moving toward focus on treatment rather than labels. #mentalhealth #DSM
nature.com
Updates to the ‘bible’ for mental-health conditions will miss the mark — is it time to ditch the DSM?
Instead of trying to refine diagnoses, we should focus on how best to give people the care that they need.
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Reposted by Jessie Tenenbaum
Barack Obama @barackobama.bsky.social · 12/02/2026
Today, the Trump administration repealed the endangerment finding: the ruling that served as the basis for limits on tailpipe emissions and power plant rules. Without it, we’ll be less safe, less healthy and less able to fight climate change—all so the fossil fuel industry can make even more money.
pbs.org
WATCH: Trump, EPA's Zeldin announce end of scientific basis for U.S. action on climate change
The Trump administration on Thursday revoked a scientific finding that long has been the central basis for U.S. action to regulate greenhouse gas emissions and fight climate change, the most aggressiv...
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Jessie Tenenbaum @jessiet1023.bsky.social · 03/02/2026
It's great seeing pioneers (even in the humanities!) exploring ways to use #AI to increase student engagement and learning, and to give them more time for interactive discussions in class. #HigherEd www.insidehighered.com/news/tech-in...
insidehighered.com
Reflections on the Value of an AI-assisted Textbook
When a UCLA professor debuted the custom textbook a year ago, other faculty criticized it as a potential threat to teaching and learning. But the textbook boosted student engagement and freed up instr...
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Jessie Tenenbaum @jessiet1023.bsky.social · 02/02/2026
Does AI already have human-level intelligence? The evidence is clear www.nature.com/articles/d41...
nature.com
Does AI already have human-level intelligence? The evidence is clear
The vision of human-level machine intelligence laid out by Alan Turing in the 1950s is now a reality. Eyes unclouded by dread or hype will help us to prepare for what comes next.
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Jessie Tenenbaum @jessiet1023.bsky.social · 22/01/2026
Great to see this work being done. I hope we see much more of it in other disease areas. #schizophrenia #GWAS #diversity www.nature.com/articles/s41...
nature.com
Biological insights into schizophrenia from ancestrally diverse populations - Nature
Genome-wide association studies incorporating data for populations of African ancestry provide an expanded view of the genetic basis of schizophrenia, which has previously been studied mainly in Europ...
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Jessie Tenenbaum @jessiet1023.bsky.social · 21/01/2026
Dear #Europe, We're so sorry. And embarrassed. -Us
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Jessie Tenenbaum @jessiet1023.bsky.social · 07/01/2026
Potentially a great use of chatbots for global mental health. (with the usual caveats...) www.theguardian.com/global-devel... #MentalHealth #GlobalHealth #LLM #AI #ChatBot
theguardian.com
The chatbot will see you now: how AI is being trained to spot mental health issues in any language
Calls to a clinic in Uganda are helping create a therapy algorithm that works in local languages, as specialists look to technology to address the global mental health crisis
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Jessie Tenenbaum @jessiet1023.bsky.social · 06/01/2026
New in NCMJ- Dr. Plasencia and I explore a statewide health data utility (HDU) as an opportunity to protect coverage for our state’s vulnerable populations. We focus on #Latine but the approach benefits many other groups as well! ncmedicaljournal.com/article/1540... #HDU #VulnerablePop #LatinX
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Jessie Tenenbaum @jessiet1023.bsky.social · 05/01/2026
I love this. :) apnews.com/article/virt...  Virtual reality opens doors for older people to build closer connections in real life #Aging #Connection #VR
apnews.com
Virtual reality opens doors for older people to build closer connections in real life
Many retirement developments serve as a tranquil refuge for older people who can no longer travel to faraway places or engage in bold adventures.
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Reposted by Jessie Tenenbaum
Scott McGrath @smcgrath.phd · 18/12/2025
Columbia and Harvard researchers find that apolitical creators are three times more persuasive than political pundits. Trust and parasocial bonds allow these influencers to shift policy preferences with unique efficacy.
wired.com
The Most Powerful Politics Influencers Barely Post About Politics
New research shows that social media creators have enormous influence over their audiences' politics—especially those who don't normally share political content.
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Jessie Tenenbaum @jessiet1023.bsky.social · 18/12/2025
Cool work I missed using #LLMs for a scoping review on use of #SDOH in #mentalHealth research. mental.jmir.org/2025/1/e67192
mental.jmir.org
Natural Language Processing and Social Determinants of Health in Mental Health Research: AI-Assisted Scoping Review
Background: The use of natural language processing (NLP) in mental health research is increasing, with a wide range of applications and datasets being investigated. Objective: This review aims to summ...
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Jessie Tenenbaum @jessiet1023.bsky.social · 11/12/2025
time.com/7338714/dr-d... #datadrivenpolicy #Mahahaha
time.com
I Left the CDC 100 Days Ago. My Worst Fears About the Agency Are Coming True
"Things have not improved," writes Dr. Debra Houry. "They have worsened. And Congress has still failed to act."
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Jessie Tenenbaum @jessiet1023.bsky.social · 01/12/2025
Women seem to retract fewer papers than men — but why? www.nature.com/articles/d41... Intriguing.
nature.com
Women seem to retract fewer papers than men — but why?
In an analysis of nearly 900 retracted medical-research studies, the number of female authors is disproportionately low.
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Jessie Tenenbaum @jessiet1023.bsky.social · 01/12/2025
Transforming mental health systems: The role of embedded researchers in advancing learning health systems - Field - 2025 - Learning Health Systems - Wiley Online Library onlinelibrary.wiley.com/doi/full/10.... #mentalhealth #LHS
onlinelibrary.wiley.com
Transforming mental health systems: The role of embedded researchers in advancing learning health systems
Background This commentary explores the critical role of embedded researchers in advancing Learning Health Systems (LHS) within the context of Canada's mental health systems. Context The Canadian ...
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