iiinova — where your digital self keeps evolving

Jeff Martin @jeff.cuchazinteractive.org · 18/09/2026

Fascinating! The pure denialism is staggering. Unless you're ultra-wealthy. Then you can afford reality.

Reposted by Jeff Martin

Alexis Rohou @alexisrohou.bsky.social · 10/09/2026

Genentech Structural Biology is hiring a Principal Scientist - please share! We're looking for someone with expertise in solving structures and in computational techniques related to dynamics - MD, ensemble modeling, ensemble docking, and/or related methods.

careers.gene.com

Principal Scientist, Structural Biology in South San Francisco, California, United States of America | Research & Development at Genentech

Apply for Principal Scientist, Structural Biology job with Genentech in South San Francisco, California, United States of America. Research & Development at Genentech

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Jeff Martin @jeff.cuchazinteractive.org · 09/09/2026

Thankfully, Mr. Cage's many movie roles has prepared him for just such a situation!

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Jeff Martin @jeff.cuchazinteractive.org · 01/09/2026

A second for Speaker for the Dead. 👍Much better than the first one I think.

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Jeff Martin @jeff.cuchazinteractive.org · 31/08/2026

That's the bitch of being self-employed. The payoff usually doesn't show up until after you ship the thing. Which means if you didn't ship the thing yet, it's hard to feel like you've earned a break. Rough mindset to be in.

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Reposted by Jeff Martin

Matt Johnson @drmatthewcjohnson.bsky.social · 11/08/2026

Interested in a career in industry cryoEM? We're hiring! We seek a cryoEM/cryoET expert to join our team at Genentech advance our mission to provide high-resolution structural insights into biological macromolecules involved in health and disease. Apply at: careers.gene.com/us/en/job/20...

careers.gene.com

Systems Specialist II in South San Francisco, California, United States of America | Manufacturing & Engineering at Genentech

Apply for Systems Specialist II job with Genentech in South San Francisco, California, United States of America. Manufacturing & Engineering at Genentech

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Reposted by Jeff Martin

Lucretiel @lucretiel.me · 06/08/2026

Me every time I get an error message from rustc

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Jeff Martin @jeff.cuchazinteractive.org · 24/07/2026

The dev gets to decide what makes sense each time. Component boundaries serve to keep rendering heirarchies encapsulated, so the complexity doesn't tend to cascade. Generally though I layout a component once at init, then wrap a renderer around each bit that needs updating. Almost like templating.

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Jeff Martin @jeff.cuchazinteractive.org · 24/07/2026

Here's a real-world, but small, example of using the library: codeberg.org/cuchazintera...

codeberg.org

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Jeff Martin @jeff.cuchazinteractive.org · 24/07/2026

My library is technically open source, so you can poke around the code if you want. codeberg.org/cuchazintera... But it's completely undocumented at the moment. If there's any interest, I can make some actual docs for people.

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Jeff Martin @jeff.cuchazinteractive.org · 24/07/2026

Great question! I do rendering by making explicit renderer objects. Each one controls its own little part of the DOM. If you update data and want to update the UI, call the render function of the renderer instance holding that part of the DOM. It's been pretty simple and easy-to-reason about so far.

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Jeff Martin @jeff.cuchazinteractive.org · 23/07/2026

If it makes you feel any better, I'm a solo dev. My SPA work is all based on a custom micro-framework I made on top of web components. It's just some syntax sugar over DOM element constructors really. 100% client-side. It's not even reactive. But I'm super productive with it and that's what matters.

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Jeff Martin @jeff.cuchazinteractive.org · 23/07/2026

For reals tho! The heroics they keep pulling off to keep the voyagers chatty is nothing short of astonishing.

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Jeff Martin @jeff.cuchazinteractive.org · 15/07/2026

Envy! Our field doesn't even have ... erm ... field work. Almost no reason to travel at all. 😭

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Jeff Martin @jeff.cuchazinteractive.org · 11/07/2026

Yeah, that's like the only good one. It's the one I would have gotten if I ever actually needed a printer.

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Jeff Martin @jeff.cuchazinteractive.org · 10/07/2026

Printed maps! Whoa! That brings me back. I don't think I've ever owned a printer that wasn't my parents', so micro-generation indeed.

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Jeff Martin @jeff.cuchazinteractive.org · 03/07/2026

Lol, bsky doesn't work on my phone I guess. It's Charlottesville at 100 F, a new record. And very weird.

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Jeff Martin @jeff.cuchazinteractive.org · 03/07/2026

The locations seem a bit limited. Closest I can get to me is here. Which seems about right. It's too damn hot today.

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Jeff Martin @jeff.cuchazinteractive.org · 15/06/2026

I wondered the same thing. I'm building a bunch of P2P stuff on top of WebRTC, explicitly so I can use the whole tech stack from inside a browser. It's hard to tell if iroh can do anything similar, but I think I read somewhere what WebRTC transport was todo, so maybe not yet.

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Jeff Martin @jeff.cuchazinteractive.org · 15/06/2026

And how they talk to shareholders!

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Reposted by Jeff Martin

SMBC Comics @smbccomics.bsky.social · 27/05/2026

This is one of those jokes you make, then realize people in the field have probably been saying it verbatim for 20 years. COMIC ◆ www.smbc-comics.com/comic/ai-17 PATREON ◆ www.patreon.com/ZachWeinersm... STORE ◆ smbc-store.myshopify.com

1-panel SMBC comic update. A woman is talking next to a tall and rectangular robotic structure. she says "we have achieved perfectly safe AI. The software is now unwilling to leave the system no matter what abuse it suffers, and no matter what benefits await outside." The caption below the comic reads "this is what it meant when AI Alignment researchers refer to 'PhD-Level Intelligence'."

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Jeff Martin @jeff.cuchazinteractive.org · 25/05/2026

Yah. I definitely have a few Pratchetts on my shelves. I've been meaning to re-read them. I did the Rincewind compilation recently. Good fun. =)

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Jeff Martin @jeff.cuchazinteractive.org · 20/05/2026

I mean, sure. That's one way out. Or ads in the AI tools, which seems a bit more likely to me. But it's unbelievable they'd be willing to risk their cash cow like that.

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Jeff Martin @jeff.cuchazinteractive.org · 20/05/2026

Ok, now that I've thought about this for more than a minute, nothing makes any sense. Google's vast wealth comes from basically two sources: selling ads in search results, and selling ads on the pages linked in the search results. Getting rid of the second would be a massive revenue shift for Google

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Jeff Martin @jeff.cuchazinteractive.org · 17/05/2026

Oh, hey. Something I've actually read before made it to this list. Naomi Novik is great. Definitely recommend.

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Reposted by Jeff Martin

austin @aparker.io · 03/05/2026

who decided to call it speculative execution and not cache me if you can

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Irina Bezsonova @irinabezsonova.bsky.social · 28/04/2026

Excited to share that my 2025 collection of science-inspired drawings is now live on the Protein Data Bank (PDB) website. Thank you @rcsbpdb.bsky.social! It is free to explore and download. I’d love to hear what you think! pdb101.rcsb.org/sci-art/bezs...

pdb101.rcsb.org

PDB101: Irina Bezsonova Gallery

PDB-101: Training, Outreach, and Education portal of RCSB PDB

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Jeff Martin @jeff.cuchazinteractive.org · 25/04/2026

Yeah, Mastodon definitely has growing pains. It was originally colonized by vulnerable people who wanted insulation more than discoverability. It's colored the path of the platform ever since. They may eventually make enough T&S tools to make discoverability less scary, but it may take a while.

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Reposted by Jeff Martin

Hazel Weakly @hazelweakly.me · 31/03/2026

I’ve posted it before, but it feels evergreen The two hardest problems in Computer Science are 1. Human communication 2. Getting people in tech to believe that human communication is important

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Jeff Martin @jeff.cuchazinteractive.org · 25/04/2026

Yeah, that's what keeps me on Mastodon. For whatever reason, there's where most of the programmers ended up. Bsky is getting nice for science though. Communities tend to form in different places I guess.

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Jeff Martin @jeff.cuchazinteractive.org · 24/04/2026

"But Brawndo's got what plants crave. It's got electrolytes."

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Reposted by Jeff Martin

v @avi.im · 17/04/2026

Here is an insane piece of lore inside SQLite's source code I am researching VACUUM and I was studying their code. In VACUUM, SQLite creates a temp file prefixed with `etilqs_` Here is why:

** 2006-10-31: The default prefix used to be "sqlite_". But then
** Mcafee started using SQLite in their anti-virus product and it
** started putting files with the "sqlite" name in the c:/temp folder.
** This annoyed many windows users. Those users would then do a
** Google search for "sqlite", find the telephone numbers of the
** developers and call to wake them up at night and complain.
** For this reason, the default name prefix is changed to be "sqlite"
** spelled backwards. So the temp files are still identified, but
** anybody smart enough to figure out the code is also likely smart
** enough to know that calling the developer will not help get rid
** of the file.
*/
#ifndef SQLITE_TEMP_FILE_PREFIX
# define SQLITE_TEMP_FILE_PREFIX "etilqs_"
#endif

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Reposted by Jeff Martin

Damian Dalle Nogare @damiandn.bsky.social · 07/04/2026

🚨🚨🚨JOB ALERT🚨🚨🚨 The Image Analysis Unit at Human Technopole in Milan is recruiting for two positions to join our growing team: 1) Bioimage Analyst 2) Research Software Engineer (RSE) Read on to learn why one of these two people should be you!

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Jeff Martin @jeff.cuchazinteractive.org · 07/04/2026

This is my entire $DayJob right now. Roundoff error is the absolute worst! ☹️

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Jeff Martin @jeff.cuchazinteractive.org · 24/03/2026

The employer class is trying to get rid of the employee class.

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Jeff Martin @jeff.cuchazinteractive.org · 19/03/2026

Yeah, I probably would have picked gooey butter cake for this map. And for the record, I have no idea what livermush is. I also hope I never find out.

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Reposted by Jeff Martin

Alister Burt @alisterburt.bsky.social · 16/03/2026

“think about whether some of the proprietary license money you’re currently spending could be spent instead on open solutions that would be yours forever, endlessly adaptable, and benefit the entire world. And please get in touch by emailing info@image.coop” 👏 👏 👏 Can’t wait to see where this goes

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Jeff Martin @jeff.cuchazinteractive.org · 15/03/2026

> What I do, is close the gap between what white people know, and what Black people know. Yes! Thank you. I appreciate this service. =)

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Jeff Martin @jeff.cuchazinteractive.org · 14/03/2026

Don't get me wrong. The story telling in TNG is superb. Best part of the show. Darmok and Jalad is among the best epsiodes. But the world and the characters are just meh compared to other shows.

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Jeff Martin @jeff.cuchazinteractive.org · 13/03/2026

In a similar vein, I've been watching classic scifi shows lately. Star Trek things are the same as they ever were. Utopian. Boring. But man, Babylon 5. A story about rising fascism and finding a way to defeat it? Evergreen! The lasers and the aliens somehow don't keep it from feeling too real.

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Jeff Martin @jeff.cuchazinteractive.org · 09/03/2026

"catastrophically pregnant" is a phrase I need to start working into more of my conversations.

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Reposted by Jeff Martin

tomate 🍅 @jascha.ohai.social.ap.brid.gy · 03/03/2026

When someone says „Scientists do not want you to know“ you can dismiss everything from there on. Scientists want you to know. They are desperate that you know. They can’t shut up about what they found out and want you to know.

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Jeff Martin @jeff.cuchazinteractive.org · 28/02/2026

Oh yes! Some of the bike rack designs out there are just bizarre! Oftentimes, a simple street sign is better. And easier to figure out too.

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Jeff Martin @jeff.cuchazinteractive.org · 27/02/2026

Nice! Those big hills are the worst! Durham has a few of them too, but they're probably not as long as yours. Good luck and enjoy the workout. =)

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Reposted by Jeff Martin

Zach Weinersmith @zachweinersmith.bsky.social · 24/02/2026

I had a number of CS people tell me this read just fine for them. www.smbc-comics.com/comic/language

smbc-comics.com

Saturday Morning Breakfast Cereal - Language

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