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Javier F Caceres

@javierfcaceres.bsky.social
783 followers 728 following 3 posts

Gene expression and RNA biology at MRC Human Genetics Unit at the University of Edinburgh. Senior editor of the RNA Journal

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Javier F Caceres @javierfcaceres.bsky.social · 03/09/2026
Our paper describing the role of SEC13 in NMD and regulation of the stress response has now been published in RNA rnajournal.cshlp.org/content/earl...
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Reposted by Javier F Caceres
Wendy Bickmore @wbickmor.bsky.social · 08/05/2026
Although cohesin-sensitive, long-range enhancer activation is equivalent in nature to proximal activation. Cooperativity can arise from different levels of activation inputs operating on a non-linear response function. @eliasfriman.bsky.social @uoe-igc.bsky.social www.biorxiv.org/content/10.6...
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Reposted by Javier F Caceres
RNA Society Journal @rnajournal.bsky.social · 13/04/2026
Excited to highlight the new Special Issue of RNA showcasing advances in system-level RNA biology, from epitranscriptomics and RNA damage to deep learning–driven structure prediction and beyond #RNAbiology #Epitranscriptomics #RNAseq #ComputationalBiology #Genomics bit.ly/4tEQL9I
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Reposted by Javier F Caceres
Institute of Genetics and Cancer @uoe-igc.bsky.social · 23/04/2026
This will be a great way to celebrate the achievements of MRC Human Genetics Unit PhD students - both current and past. Please share far and wide!
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Javier F Caceres @javierfcaceres.bsky.social · 02/05/2026
Our preprint describing the moonlighting functions of SEC13 in NMD and regulation of the UPR is out now in bioRxiv www.biorxiv.org/cgi/content/...
biorxiv.org
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Reposted by Javier F Caceres
Markus Landthaler @landthalerm.bsky.social · 12/09/2025
Very harmonious and inspiring collaboration with Niels Gehring, @volkerboehm.bsky.social and team at Uni Köln, and colleagues at @mdc-berlin.bsky.social . Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome: Molecular Cell www.cell.com/molecular-ce...
cell.com
Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome
UPF1 depletion inhibits nonsense-mediated mRNA decay (NMD) and stabilizes direct target transcripts within hours. Boehm et al. use conditional protein degradation and advanced transcriptomics to map t...
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Reposted by Javier F Caceres
Institute of Genetics and Cancer @uoe-igc.bsky.social · 15/08/2025
A drug candidate for hard-to-treat cancers, developed by Profs Neil Carragher and Asier Unciti-Broceta at #IGC and licensed to Nuvectis Pharma, has moved to the next stage of clinical trials. Read more here: edin.ac/3UuvJeo @edinnovations.bsky.social
edin.ac
Life-saving cancer drug takes next step in clinical development | Institute of Genetics and Cancer | Institute of Genetics and Cancer
A drug candidate for hard-to-treat cancers, developed in the Institute of Genetics and Cancer (IGC) and now licensed to Nuvectis Pharma, has moved to the next stage of clinical trials after successful...
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Reposted by Javier F Caceres
OMühlemann lab @omuhlemann-lab.bsky.social · 11/02/2025
Congratulations to David Tollervey! He received this year's RNA Society Lifetime Achievement in Science Award. @rnasociety.bsky.social
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Javier F Caceres @javierfcaceres.bsky.social · 19/11/2024
Join us in San Diego. A great meeting and also featuring the RNA Journal
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Reposted by Javier F Caceres
Barbara Mellone 🇺🇦 @centromellone.bsky.social · 18/11/2024
Our paper on a centromere-enriched retroelement is out! link.springer.com/article/10.1... Congratulations to all the authors! Comments and reposts welcome and appreciated 🧬🔬
link.springer.com
Transcription of a centromere-enriched retroelement and local retention of its RNA are significant features of the CENP-A chromatin landscape - Genome Biology
Background Centromeres depend on chromatin containing the conserved histone H3 variant CENP-A for function and inheritance, while the role of centromeric DNA repeats remains unclear. Retroelements are...
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Reposted by Javier F Caceres
Jeff Coller @jmcoller.bsky.social · 18/11/2024
Looking for a new home to share all things RNA. That other place was just too crazy. Excited to see so many old RNA friends here on this platform! #RNA
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Reposted by Javier F Caceres
Sara MaciasRNA @saramaciasrna.bsky.social · 18/11/2024
New EdiRNA events for the new year! Funded by the @RNASociety. Great opportunity to network with other RNA biologists 🧬 (dsRNA included) from Edinburgh and beyond 🚀 Jan 29, 2025 Apr 9, 2025 Jun 11, 2025 Oct TBD, 2025 www.edirna.com/meetings
edirna.com
EVENTS | EdiRNA
ediRNA aims to establish new collaborations, encourage scientific discussion, and enhance interactions between RNA researchers across Edinburgh.
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