A Review of de novo protein design highlights key methodological advances and achievements, current challenges and future applications.

The four major isoforms encoded by RAS proto-oncogenes are differentially associated with cancer, but there are few isoform-specific binding reagents …

The Trump administration has frozen roughly $200 million in National Science Foundation, National Institutes of Health and other federal agency-funded research at UCLA, citing allegations the school discriminates in admissions and has failed to protect the civil rights of Jewish students.

Protein quality control (PQC) is carried out in part by the chaperone Hsp70 in concert with adapters of the J-domain protein (JDP) family. The JDPs, a…

Computationally designed sensors map the activity and signaling environment of Ras.