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Jack Goodall

@jackwgoodall.bsky.social
2K followers 1.7K following 37 posts

Sheffield Infectious Diseases Registrar // NIHR researcher // Interested in molecular diagnostics and transmission modelling // Lover of art, literature, fermentation and the great outdoors //

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Reposted by Jack Goodall
Dariia Mykhailyshyna @dariia.bsky.social · 19/07/2026
❗️Our next workshop will be on July 23rd, 6 pm CET on Introduction to Bayesian Multiple Imputation with the rblimp package Register or sponsor a student by donating to support Ukraine! Details: bit.ly/3wBeY4S Please share! #AcademicSky #EconSky #RStats
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Jack Goodall @jackwgoodall.bsky.social · 02/07/2026
Is it possible there is a grain of truth in their (admittedly alarming) assertion?Although there are often the wrong covariates in regression models, the right ones (ie all the unmeasured true confounders) are often missing too…
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Adam Kucharski @adamjkucharski.bsky.social · 30/06/2026
New post, on why we should stop telling people the normal distribution is in places that it isn't: kucharski.substack.com/p/no-the-nor...
kucharski.substack.com
No, the normal distribution isn't in your gym
And we should stop telling people it is
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Jack Goodall @jackwgoodall.bsky.social · 09/06/2026
Two really useful reports on the Bundibugyo #Ebola outbreak from the @cmmid-lshtm.bsky.social team at LSHTM: - The multitude of benefits that safe and dignified burial can bring - The risk of exported cases cmmid.github.io/topics/ebola... #IDSky
cmmid.github.io
Ebola BVD
Repository with work from the Centre for the Mathematical Modelling of Infectious Diseases (CMMID) at the London School of Hygiene & Tropical Medicine (LSHTM).
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Sam Abbott @seabbs.bsky.social · 22/05/2026
Estimating the current size of the 2026 DRC Bundibugyo virus outbreak: a joint Bayesian re-analysis of the McCabe et al. report w/ @kathsherratt.bsky.social Sam Brand and @sbfnk.bsky.social
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Jack Goodall @jackwgoodall.bsky.social · 06/05/2026
Agree very good evidence that P2P can happen with this strain (and fair enough a cruise ship is a prime spot). It may well be what is going on here. I just don't think that a doctor has fallen ill is enough to implicit criticise their PPE. Could have acquired from the rats or whilst socialising...
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Jack Goodall @jackwgoodall.bsky.social · 06/05/2026
Just before we are too critical of a doctor with a though gig - person to person spread of hatavirus is rare. I think it’s most likely that they were exposed to the same rodent urine/dropping as the other passengers. #IDsky
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Jack Goodall @jackwgoodall.bsky.social · 29/04/2026
It's always hard to judge generalisability but I think when the margins are as (relatively) tight then I agree you should think pretty hard about it. Seem to me this is much more applicable in micro studies where bacteria keep moving the goal posts...
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Jack Goodall @jackwgoodall.bsky.social · 29/04/2026
I like the idea of a 'proximity weighting' in meta-analysis - is that already a thing?? Agree generalisability is tricky here and the hint of a temporal trend is worrying.
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Jack Goodall @jackwgoodall.bsky.social · 29/04/2026
(Incidentally @nejm.org' NEJM Evidence has excellent typography and design. @jama.com could take note 🙃)
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Jack Goodall @jackwgoodall.bsky.social · 29/04/2026
However, the pooled relative risk for hospital mortality of 0.91 (CrI 0.82-0.99) is impressive. I think we've either got to argue that that number is wrong or figure out a way to safely implement this. I've written a longer blog post on this here: jackwgoodall.github.io/infection_up...
jackwgoodall.github.io
Selective Decontamination of the Digestive Tract in ventilated patients: A Bayesian meta-analysis – Infection & Global Health Research Updates
Mounting evidence in support of a controversial intervention
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Jack Goodall @jackwgoodall.bsky.social · 29/04/2026
Protecting the world from AMR and the individual from long-term damage to their microbiome (www.nature.com/articles/s41...) seem like two excellent reason not to use antibiotics unless you really need them...
nature.com
Antibiotic use and gut microbiome composition links from individual-level prescription data of 14,979 individuals - Nature Medicine
Using individual-level data from the Swedish Prescribed Drug Register and fecal metagenomes of 14,979 individuals in Sweden, the authors examined the association between oral antibiotic use over 8 yea...
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Jack Goodall @jackwgoodall.bsky.social · 29/04/2026
I'm pretty convinced by the recent Bayesian meta-analysis of selective decontamination of the digestive tract for ventilated patients. evidence.nejm.org/doi/10.1056/... I have to admit that I instinctively *really* don't like this as an idea (but hey - I guess that's what RCT evidence is for) #IDSky
evidence.nejm.org
Selective Decontamination of the Digestive Tract in Adult Mechanically Ventilated Patients — An Updated Systematic Review with Bayesian Meta-Analysis
There is uncertainty whether the use of selective decontamination of the digestive tract (SDD) as a preventive antimicrobial strategy reduces mortality in adult patients receiving mechanical ventil...
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Joseph Marcus @josephmarcusid.medsky.social · 22/04/2026
So far SNAP RCTs have confirmed my practices: 1) ✅ cefazolin 2) ❌ clindamycin #IDSky
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Dr Roz Eggo @rozeggo.bsky.social · 12/04/2026
Great speakers at this symposium - 22 April 2026 at LSHTM. Join online or in person (email if in person) to hear great talks at the cutting edge of Inequalities in infectious disease dynamics. www.lshtm.ac.uk/newsevents/e...
lshtm.ac.uk
Inequalities in infectious disease dynamics symposium | LSHTM
Join us for the Social Inequalities in Infectious Disease Dynamics Symposium at the London School of Hygiene & Tropical Medicine (LSHTM). The day features a full programme of presentations and invited
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Jack Goodall @jackwgoodall.bsky.social · 07/04/2026
Lenacapavir is a great HIV prevention drug and I really hope Gilead agree to MSF's request to sell it to them so they can provide it to those who patently need it most. Some thoughts here: jackwgoodall.github.io/infection_up... #IDsky #globalhealth
jackwgoodall.github.io
MSF calls on Gilead to start selling them lenacapavir – Infection & Global Health Research Updates
A punchy open letter from MSF to Gilead
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Jack Goodall @jackwgoodall.bsky.social · 02/04/2026
This is indescribably sad development in an already appalling man-made humanitarian crisis
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Daniel Padfield @padpadpadpad.bsky.social · 30/03/2026
PLEASE SHARE. PhD Opportunity with me, Ben Raymond and Jan Engelstaedter and Andrew Letten at University of Queensland. Experimentally testing mechanisms of how temperature may change selection and spread of AMR in E. coli. Coupled with some advanced modelling and sequencing. 🧪🦠 #microsky
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Global Society for Infectious Disease Dynamics (GSIDD) @gs-idd.bsky.social · 18/03/2026
1/ Announcing the IDD Connect Series! #IDsky #EpiSky 🧪 ❓Interested in hearing from infectious disease dynamics organizations from different regions? 📣 IDD Connect is a monthly initiative to bring together the infectious disease dynamics global community 📧 Join GSIDD mailing list for event links👇
gsidd.org
Join Us | GSIDD
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Jack Goodall @jackwgoodall.bsky.social · 24/03/2026
Yes I've been really enjoying those - like you say their focus seems to be on clinical trials and trial methodology. I'll add a link to them in the resources section
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Jack Goodall @jackwgoodall.bsky.social · 24/03/2026
And if you don't work in ID - firstly I'm very sorry to hear that - but if you like the journal feed and would like to replicate it for your speciality, its open sourced on my github and I would be happy to walk you through it
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Jack Goodall @jackwgoodall.bsky.social · 24/03/2026
A few colleagues have kindly agreed to help write the blog updates - but the more the merrier - if you would like that contribute that would be amazing - please get in touch. Please also let me know if there are ways it could be improved or journals/resources that should be added.
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Jack Goodall @jackwgoodall.bsky.social · 24/03/2026
I've made a website for clinically relevant infection research: jackwgoodall.github.io/infection_up... It's in its early days but it has summaries of recent infection papers that caught my eye, an OpenAlex feed of recent infection papers from high impact journal and a resources section #IDSky
jackwgoodall.github.io
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Jack Goodall @jackwgoodall.bsky.social · 24/03/2026
This would make a great review 😉 jackwgoodall.github.io/infection_up...
jackwgoodall.github.io
Blog – Infection Research Updates
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Angie Rasmussen @angierasmussen.bsky.social · 21/04/2025
So this interview lasted 2 hours so this “you’re scaring me” part might seem like an overreaction or fearmongering to someone without that context. There’s a lot of evidence to support my hypothesis that a potential H5N1 pandemic would be worse than COVID.
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josh farkas 💊 @pulmcrit.bsky.social · 17/01/2025
ID gurus - what are your thoughts on the optimal tx for S. pneumo meningitis that is pansensitive? ESCMID guidelines: PCN or amp/amox IDSA guidelines: PCN NICE guidelines: Ceftriaxone PCN: lower risk of CDiff, antimicrobial stewardship rizz Ceftriaxone: fewer infusions, pt already on this #IDsky
media.tenor.com
a woman says " i feel the conflict in you "
ALT: a woman says " i feel the conflict in you "
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Jack Goodall @jackwgoodall.bsky.social · 03/01/2025
The danger of course is that this nuance is lost on whoever orders the test and TB gets erroneously “ruled out”. This seems to be more of an issue of education and result presentation that an intrinsic fault in the test
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Jack Goodall @jackwgoodall.bsky.social · 03/01/2025
I’ve often wondered about whether we are too dogmatic about this in ID. There are lots of tests (eg all of the physical exam!) that have comparably bad performance characteristics. We don’t pretend they are 100 sens/spec but understand their limitations and do a good bit of Bayesian inference
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Jack Goodall @jackwgoodall.bsky.social · 25/11/2024
Great summary Alasdair. I suspect asymptotic carriage is less of a phenomenon in adults - but still happens. Some of my colleagues would argue though that the specificity is near enough 100% in adults that the diagnosis is made when you get a +ve (NPS) PCR. Anyone got thoughts (or a reference!)?
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SHORTEN-2 trial @shorten2trial.bsky.social · 21/11/2024
Our @shorten2trial.bsky.social aims to confirm that 7-day treatments are superior to 14-day courses for uncomplicated P. aeruginosa BSI. Check out our full protocol 👉🏻 journals.plos.org/plosone/arti... #AMSsky #IDSky
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Reposted by Jack Goodall
Hayley Colton @xhayles.bsky.social · 19/11/2024
💉 How do we optimise the neutralising antibody responses of HSCT/CAR-T recipients following COVID vaccination? We found ChAdOx1-S recipients were EIGHT times more likely to have neutralising antibodies than those receiving mRNA vaccines in our new paper! Read more --> doi.org/10.1111/bjh....
doi.org
Greater preservation of SARS‐CoV‐2 neutralising antibody responses following the ChAdOx1‐S (AZD1222) vaccine compared with mRNA vaccines in haematopoietic cell transplant recipients
Knowledge of factors impacting immune responses after COVID-19 vaccination is essential for guiding revaccination strategies in haematopoietic stem cell transplant (HSCT) and chimeric antigen recepto...
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Jack Goodall @jackwgoodall.bsky.social · 20/11/2024
Ah amazing - glad you liked it! Please do feel free to add to it
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Thushan de Silva @thushan-desilva.bsky.social · 12/11/2024
BIA now on blue sky 👏 - and please consider applying for our ECR and small project grants!
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Jack Goodall @jackwgoodall.bsky.social · 10/11/2024
A global health starter back would be a great public service. I’m an ID clinical academic currently working on bacterial/viral confection in West Africa
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Jack Goodall @jackwgoodall.bsky.social · 08/11/2024
This is a really useful insight that hopefully will guide how we prevent future spill overs
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Jack Goodall @jackwgoodall.bsky.social · 08/11/2024
Looks like the link Bluesky has made doesn’t work - but clicking the link directly in the text is fine
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Jack Goodall @jackwgoodall.bsky.social · 08/11/2024
It's fine on a phone but best read on a browser. This project started life as a custom markdown template for our research group. The tutorial links to that package and has a section at the bottom on customising the logo and branding for your lab/group.
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Jack Goodall @jackwgoodall.bsky.social · 08/11/2024
R markdown is an amazing way to share pre-publication findings with colleagues and collaborators. If you use R but haven't taken advantage of markdown then I have a tutorial just for you: jackwgoodall.github.io/floreytemplate It's new so I would love your feedback. #IDsky #AcademicSky #episky
jackwgoodall.github.io
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Eurosurveillance journal @eurosurveillance.org · 04/11/2024
New to this place 🦋, moving on from the other place Here to provide you #EpiSky #IDsky updates from Europe's weekly, peer-reviewed scientific journal on infectious disease epidemiology, prevention & control #PublicHealth Submit your papers now for our annual theme 2025 😷💉 bit.ly/annualtheme25
IMage showing vaccine vials, resarchers etc to illustrate the call for the Eurosurveillance annual theme 2025: "Vaccine-preventable diseases in humans — today's challenges and tomorrow's opportunities"
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Jen Golbeck @jengolbeck.bsky.social · 02/11/2024
🧵Next week, you will see people using something called Benford's Law to try to prove election fraud. ⛔️These people are wrong⛔️ I am a scientist who has published on Benford's Law. Let me tell you what it is and why what they are doing is mathematically incorrect. 1/
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Jack Goodall @jackwgoodall.bsky.social · 30/10/2024
(Key **players** this should say!)
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Jack Goodall @jackwgoodall.bsky.social · 30/10/2024
I was lucky enough to work on the AMBITION trial (although had nothing to do with the design) and it has to be said that their motivation was to improve treatment options in low resource settings. This is just a happy bonus.
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Jack Goodall @jackwgoodall.bsky.social · 30/10/2024
But PICC lines and hospitalisation are risky anywhere (especially if you have no immune system). This feels especially relevant to people how are surprisingly well with crypto but would be very vulnerable to nosocomial complications.
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Jack Goodall @jackwgoodall.bsky.social · 30/10/2024
The design is very smart as it has hard fungal dynamic outcomes too. If it didn’t have this then you could easily argue that the risks/benefits of hospitalisation and long term IV access could be different in different countries.
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Jack Goodall @jackwgoodall.bsky.social · 30/10/2024
There is an excellent article by the key player in the AMBITION-cm trial on just this topic: academic.oup.com/cid/article/....
academic.oup.com
How Applicable Is the Single-Dose AMBITION Regimen for Human Immunodeficiency Virus–Associated Cryptococcal Meningitis to High-Income Settings?
The AMBITION-cm trial showed that a single, high dose of liposomal amphotericin B, given with oral fluconazole and flucytosine, is an effective treatment f
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Jack Goodall @jackwgoodall.bsky.social · 23/10/2024
This is an amazing idea - using microbiome assessments to account for the inaccuracies that are invariably present in self reported diet recall www.nature.com/articles/s41...
nature.com
Microbiome-based correction for random errors in nutrient profiles derived from self-reported dietary assessments - Nature Communications
Here, the authors introduce METRIC, a deep-learning method that corrects measurement errors in self-reported dietary nutrient profiles using assessed data and microbial composition, effectively enhanc...
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Jack Goodall @jackwgoodall.bsky.social · 18/10/2024
Amazing public service. Thank you!
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Ilan Schwartz @germhuntermd.bsky.social · 18/10/2024
Dear IDTwitter refugees I made an #IDSky starter pack which makes it easy to find accounts of ID clinicians, medical microbiologists, ID researchers, ID epidemiologists, ID focused reporters, and of course journals ahead of the curve. Let me know if I missed you! go.bsky.app/LnAQjdq
media.tenor.com
patrick star from spongebob squarepants is standing on a sandy beach next to a black line .
ALT: patrick star from spongebob squarepants is standing on a sandy beach next to a black line .
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Angela Huttner @angelahuttner.bsky.social · 11/10/2024
Did it. Got approval to stop posting at X. Please #IDSky #MedSky people, feel free to follow @cmicomms.bsky.social, ESCMID's #OpenAccess journal on all things #infectiousdiseases, #clinicalmicrobiology, #AMR, and host of the #Communicable podcast, so I can show that we were right! :-)
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