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Izabella A. Pena, PhD 🇧🇷🇨🇦

@izabellapena.bsky.social
726 followers 905 following 51 posts

#newPI @ Children’s Hospital of Eastern Ontario Research Institute (CHEO-RI), Assist. Professor, University of Ottawa @uottawamed.bsky.social 🇧🇷in🇨🇦 www.penalab.ca Former @MIT_Picower #rarediseases #vitamins #metabolism #genetics #zebrafish #newMom

PostsRepliesMedia
Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
NFL Daily News @insidenflnews.bsky.social · 09/02/2026
Bad Bunny “together we are America”
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Jim Acosta @jimacosta.bsky.social · 08/02/2026
BREAKING: The Epstein survivors are releasing this ad on this Super Bowl Sunday to send the message that they will not “move on” from the largest sex trafficking scandal in the world. #standwithsurvivors
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Outspoken™️ @out5p0ken.bsky.social · 03/02/2026
Stop saying underage women. They are children.
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Robert Reich @rbreich.bsky.social · 02/02/2026
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CJ Fogler @cjzero.bsky.social · 02/02/2026
Billie Eilish: "No one is illegal on stolen land"
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Jeff Nascimento @jnascim.info · 12/01/2026
O AGENTE SECRETO → MELHOR FILME INTERNACIONAL #GoldenGlobes  🇧🇷🇧🇷🇧🇷
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Matt Olm @mattolm.bsky.social · 17/10/2025
My fantastic department at CU Boulder is hiring a tenure-track Assistant Professor! This is a broad search spanning nearly all areas of biology. Applications are due Nov 13, 2025. Feel free to reach out to me with questions, and please share widely. jobs.colorado.edu/jobs/JobDeta...
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Princess Vimentin PhD | Cancer Biologist @princess-vimentin.bsky.social · 09/10/2025
This life on planet earth isn’t the end. The consciousness survives. We are part of Mother Nature. You get to choose the difference that you make. #Pinks
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Izabella A. Pena, PhD 🇧🇷🇨🇦 @izabellapena.bsky.social · 02/10/2025
Just a reminder that vaccines are safe and the best tool to protect you and your loved ones from sickness. More than 1.2 million pregnant women vaccinated against Covid-19 (including myself) and research shows clear benefits from mother and baby. #vaccinesAREsafe
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Izabella A. Pena, PhD 🇧🇷🇨🇦 @izabellapena.bsky.social · 02/10/2025
My lab (1st photo), together with the Djaoud lab (2nd photo) took a little break from the lab to enjoy the stunning fall colors and crisp air at Gatineau Park. It was a refreshing gathering, full of connection and shared appreciation for each other, celebrating the accomplishments this past semester
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Brooke Newman @brookenewman.bsky.social · 01/10/2025
RIP Jane Goodall. Fellow difficult women everywhere salute you.
A photo of and quote by Jane Goodall: “ it actually doesn’t take much to be considered a difficult woman. That’s why there are so many of us.”
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Katharine Hayhoe @katharinehayhoe.com · 01/10/2025
The world has lost its most powerful advocate for nature and hope. Yet many remain who will continue her legacy and I know she will continue to inspire generations more.
A screenshot of a post by the Jane Goodall Institute on LinkedIn stating that they learned that Dr. Goodall passed away due to natural causes in California while on her speaking to her current speaking tour there.
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Scott P. Egan @scottpegan.bsky.social · 14/08/2025
A friendly reminder from the Common Five-lined Skink (Plestiodon fasciatus), who weighs 9 grams on a good day… Never give up.
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Joao Pereira @jdpereira.bsky.social · 14/06/2025
I haven’t shared this before but it is worth remembering - the day I was offered my first position leading a lab/core (at Yale), with a substantial start up, I was rejected from a Portuguese institution my application got 60%. Faculty positions are not dependent on you alone - keep trying.
media.tenor.com
a man pointing to a sign that says believe
ALT: a man pointing to a sign that says believe
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Kevin M. Kruse @kevinmkruse.bsky.social · 12/06/2025
(Attenborough voice) Behold the majestic splendor of the North American Rescue Mutt, master of all he surveys in this suburban yard
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 10/06/2025
“You can get a other job, but you cannot get another soul”.
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uOttawa @uottawa.ca · 09/06/2025
We’re all getting so emotional here! 🥹Time moves so fast - congratulations to all graduates! Savour this moment! #uograd25
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Izabella A. Pena, PhD 🇧🇷🇨🇦 @izabellapena.bsky.social · 08/06/2025
Celebrating the first MSc graduation from my lab, Rahima Hasmani! It was a truly wonderful experience to mentor you through your science journey. I’m very proud of you and I’m excited to follow your next journey! Viva! #uoGrad25
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
A Returning Doctor @returningdoctor.bsky.social · 24/05/2025
Samantha Anthony: Career breaks should be supported, not feared 'We owe it to ourselves and to our patients to take time out when we need to' #PermittedToPause blogs.bmj.com/bmj/2018/03/...
blogs.bmj.com
Samantha Anthony: Career breaks should be supported, not feared - The BMJ
We owe it to ourselves and to our patients to take time out when we need to As I near the end of a one year career break, it has [...]More...
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 24/05/2025
David Liu @harvard.edu beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors 👏 youtu.be/8YhJM6zxYDw?...
youtu.be
Breakthrough Prize-Winning Biochemist on the Deadly Cost of Funding Cuts | Amanpour and Company
YouTube video by Amanpour and Company
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Nature @nature.com · 21/05/2025
Molecules in urine and blood can reveal how much of a person’s diet comes from ultra-processed foods go.nature.com/4kybHea
go.nature.com
How much ultra-processed food do you eat? Blood and urine record it
Samples could provide an objective measure of diets and help to unravel their contribution to disease.
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Daniel MacPhee 🇨🇦 @d-macphee.bsky.social · 19/05/2025
“demethylation isn't universally required for formation of an early mammalian embryo, because the opossum embryo develops without being fully wiped of this epigenetic mark…wiping may have evolved specifically for the development of the placenta.” #ReproSky #Placenta www.crick.ac.uk/news-and-fea...
crick.ac.uk
Marsupial research reveals how mammalian embryos form
Researchers at the Francis Crick Institute have revealed insight into why embryos erase a key epigenetic mark during early development, suggesting this may have evolved to help form a placenta.
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
European Research Council (ERC) @erc.europa.eu · 19/05/2025
Are you based in the U.S. 🇺🇸 or Canada 🇨🇦 and thinking of doing research in Europe? ERC grants offer up to €4.5 million to support groundbreaking, investigator-driven frontier research in all fields. Watch the dedicated info session for researchers in your region👉 youtu.be/92QYink1Lik #ChooseEurope
youtu.be
ERC Grants: EU funding for your bottom-up research proposal (2025)
YouTube video by EURAXESS North America
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 15/05/2025
This is what can be achieved today due to longstanding federal support of academic basic science alongside close partnership of universities, private industry and NIH intramural initiatives. An ecosystem worth not just saving but doubling down on! innovativegenomics.org/news/first-p...
innovativegenomics.org
First Patient Treated with Personalized CRISPR Therapy, Developed in Just Six Months
The first on-demand CRISPR therapy for an infant with a rare metabolic disease developed by the IGI and collaborators around the world.
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Christian Frezza @frezzalab.bsky.social · 15/05/2025
Whoa!! www.nejm.org/doi/full/10....
nejm.org
Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease | NEJM
Base editors can correct disease-causing genetic variants. After a neonate had received a diagnosis of severe carbamoyl-phosphate synthetase 1 deficiency, a disease with an estimated 50% mortality ...
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Michelle Collins @mmcollins.bsky.social · 08/05/2025
What a great day of zebrafish research! Thanks to everyone who shared their amazing work at the 3rd CZRC and congrats to our award winners!
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Aaron Quinlan (he/him) @aaronquinlan.bsky.social · 28/04/2025
The Department of Human Genetics at the University of Utah is sponsoring the Rising Stars in Genetics and Genomics symposium! - We are seeking nominations bu June 1. - September 18-19, 2025 - Please share with the star postdocs that you know. docs.google.com/forms/d/e/1F...
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Senator Bernie Sanders @sanders.senate.gov · 11/05/2025
Ages 0-4 are the most important, emotionally & intellectually, in human development. Yet, in the US, we have a very high rate of childhood poverty and a broken child care system. Congratulations to New Mexico for leading the way forward for high quality, free child care. Other states must follow.
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Izabella A. Pena, PhD 🇧🇷🇨🇦 @izabellapena.bsky.social · 02/05/2025
Just had an incredible week at the Bellairs Research Institute, McGill, discussing CRISPR and functional genomics with brilliant folks. It was, without a doubt, the best scientific meeting I've ever attended! Super small and informal meeting, with plenty of time for discussions and work at the beach
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
André K. Isaacs @drdre4000.bsky.social · 25/04/2025
Today we learned the Diels-Alder Reaction
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womensartbluesky.bsky.social @womensartbluesky.bsky.social · 26/04/2025
Portuguese textile artist Vanessa Barragão's large-scale handwoven artworks using techniques of her ancestors such as latch hook, crochet and felt needle with recycled materials #womensart
Photo featuring a white woman sitting crossed legged  wearing white shirt and trousers sitting on and in front of a  huge textile artwork resembling an eco system in greens browns and blue
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Dylan MacKay @dylanmackayphd.bsky.social · 12/04/2025
Dear Canadian researchers, faculty, RAs, PDFs and grad students, this letter is for the federal party leaders asking them to defend and expand Canadian research sovereignty with a historic investment in science, please sign and share docs.google.com/document/d/1...
docs.google.com
National Letter
Open Letter from Canadian Researchers to the Federal party leaders Click here to sign this letter See who has signed - version française se trouve à page 3 - Dear Party Leaders We, the undersigne...
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Christian Frezza @frezzalab.bsky.social · 23/04/2025
www.nature.com/articles/s41...
nature.com
Microbial metabolite drives ageing-related clonal haematopoiesis via ALPK1 - Nature
ADP-heptose binds to ALPK1, triggering transcriptional reprogramming and NF-κB activation, endowing pre-leukaemic cells with a competitive advantage due to excessive clonal proliferation.
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
🎮 Dr. Gremlin 😈 (they/she/any) @colorless.green · 21/04/2025
so they're mycoblogging
Headline that says mushrooms may talk to one another with up to 50 words
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Katie Mack @astrokatie.com · 22/04/2025
“The release of the Nature Careers jobs-board data follows a separate poll of researchers by Nature’s news team, which found that 75% of researchers in the United States who responded were keen to leave.” #BrainDrain 🧪
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Daniel MacPhee 🇨🇦 @d-macphee.bsky.social · 19/04/2025
Recruiting U.S. scientists is a fine idea – except we’re barely supporting Canadian scientists as it is “this sounds like an excellent idea, except for one detail: There are insufficient funds for those of us who are already here.” #Canada #Research #cdnpoli www.theglobeandmail.com/opinion/arti...
theglobeandmail.com
Opinion: Recruiting U.S. scientists is a fine idea – except we’re barely supporting Canadian scientists as it is
Before we look to take advantage of fleeing American talent, let’s nurture the Canadian talent we have here by increasing R&D spending
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Molly Jong-Fast @mollyjongfast.bsky.social · 15/04/2025
Good for Harvard
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Eoin Higgins @eoinhiggins.bsky.social · 15/04/2025
MIT following Harvard's lead here
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Barack Obama @barackobama.bsky.social · 15/04/2025
Harvard has set an example for other higher-ed institutions - rejecting an unlawful and ham-handed attempt to stifle academic freedom, while taking steps to make sure students can benefit from an environment of intellectual inquiry, rigorous debate and mutual respect. Let’s hope others follow suit.
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Molly Schumer @mollyschumer.bsky.social · 10/04/2025
With @hybridzones.bsky.social & @jenncoughlan.bsky.social, we have been working on an update to Daven Presgraves' influential 2010 review on hybrid incompatibilities (shorturl.at/cJndf). The preprint is available here (shorturl.at/DTC48) with an updated table of almost 100 incompatibilities!
shorturl.at
The molecular evolutionary basis of species formation - Nature Reviews Genetics
Recently, several new speciation genes have been identified that have contributed to our understanding of the molecular details of the evolution of hybrid dysfunction. This Progress article describes ...
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Vaishnavi Ananthanarayanan (She/Her) @vaishananth.bsky.social · 09/04/2025
How is mitochondrial volume maintained across successive generations of dividing cells? In our new preprint, we show how fission yeast cells use mitochondrial activity to control division timing and maintain mitochondrial homeostasis! (1/n) 📖 www.biorxiv.org/content/10.1...
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Nature Biotechnology @natbiotech.nature.com · 09/04/2025
Proteome-wide measurements of dose–response curves for 144 drugs reveal drug mechanisms of action go.nature.com/4a9lMs8 rdcu.be/egMl1
go.nature.com
Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics - Nature Biotechnology
Proteome-wide measurements of dose–response curves for 144 drugs reveal drug mechanisms of action.
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Eric Topol @erictopol.bsky.social · 09/04/2025
A huge day for mapping in life science! —the mammalian brain, most extensive yet (10 papers @nature.com journals) nature.com/articles/s41... @alleninstitute.bsky.social —a comprehensive map of the human cell->sub-cellular nature.com/articles/s41... —complete ape genomes nature.com/articles/s41...
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Alessandro Nai @alessandronai.bsky.social · 29/03/2025
Partial eclipse over Amsterdam proydly brought to you by Our Supreme Lord Sauron #eclipse
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Iain Cheeseman @iaincheeseman.bsky.social · 28/03/2025
New preprint drop! Check out work from @jimmy-ly.bsky.social et al for how protein isoforms generated by alternate translation initiation create dual localization, contribute to mitochondrial function, and are mutated in disease. "Blue-tutorial" thread below. www.biorxiv.org/content/10.1...
biorxiv.org
Alternative start codon selection shapes mitochondrial function during evolution, homeostasis, and disease
Mitochondrial endosymbiosis was a pivotal event in eukaryotic evolution, requiring core proteins to adapt to function both within the mitochondria and in the host cell. Here, we systematically profile...
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Reposted by Izabella A. Pena, PhD 🇧🇷🇨🇦
Eric Topol @erictopol.bsky.social · 26/03/2025
Discovery of a new class of natural antibiotics with a new mode of action to address antimicrobial resistance, a major unmet need @mcmasteruniversity.bsky.social @nature.com www.nature.com/articles/s41...
nature.com
A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome - Nature
A new lasso peptide antibiotic exhibits broad-spectrum activity against Gram-negative and Gram-positive bacteria by interfering with bacterial protein synthesis, is unaffected by common resistanc...
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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 27/03/2025
We are seeking to hire a lab tech, this is an HHMI funded position, please share the job posting: hhmi.wd1.myworkdayjobs.com/en-US/Extern...
hhmi.wd1.myworkdayjobs.com
Lab Administration Research Technician- Bertozzi Lab
Primary Work Address: Beckman Center, Stanford, CA, 94305-5323 Current HHMI Employees, click here to apply via your Workday account. We are currently looking for a highly motivated Lab Administration ...
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Christian Frezza @frezzalab.bsky.social · 26/03/2025
www.nature.com/articles/s41... A human brain map of mitochondrial respiratory capacity and diversity
nature.com
A human brain map of mitochondrial respiratory capacity and diversity - Nature
The ability to physically partition the human brain at a spatial resolution comparable to neuroimaging methods enabled the development of a brain-wide atlas of mitochondrial content, specialization an...
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