Isa Moreno @isabmor.bsky.social · 22/01/2026It’s finally here! 🎉 Delayed a bit by the classic post-PhD lab change, but very happy to see this work published. Thank you @lionelguy.bsky.social and @sellinlab.bsky.social 😄 031
Reposted by Isa MorenoHugo Bisio @molbiolgv.bsky.social · 27/08/2025Finally out! Did you ever wonder how a phylum with 10 core genes can make a conserved organelle? Read the paper! It's all about intrinsically disordered proteins! | PNAS www.pnas.org/doi/10.1073/...pnas.orgPNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans... 196
Reposted by Isa MorenoMolecular Biology and Evolution @molbioevol.bsky.social · 05/08/2025Moreno, @lionelguy.bsky.social et al. applied experimental evolution to identify genes conferring host specificity to L. pneumophila, highlighting the importance of mutations targeting the LerC protein and the LPS synthesis cluster. 🔗 doi.org/10.1093/molbev/msaf161 #evolbio #molbio #legionelladoi.orgHost-Specific Adaptation of Legionella pneumophila to Single and Multiple HostsAbstract. Legionella pneumophila is an endosymbiotic bacterial species able to infect and reproduce in various protist and human hosts. Upon entry into hum 075
Reposted by Isa MorenoHugo Bisio @molbiolgv.bsky.social · 15/02/2025Here our revised version of our manuscript defining viral factories as biomolecular condensates. Hope you enjoy the reading. www.biorxiv.org/content/10.1...biorxiv.orgNucleocytoviricota viral factories are transient organelles made by liquid-liquid phase separationPhase separation is a widespread mechanism in viral processes, mediating replication, host manipulation and virion morphogenesis. The phylum Nucleocytoviricota encompasses diverse and ubiquitous virus... 042