Reposted by Lionel Guy
Moreno, @lionelguy.bsky.social et al. applied experimental evolution to identify genes conferring host specificity to L. pneumophila, highlighting the importance of mutations targeting the LerC protein and the LPS synthesis cluster.
🔗 doi.org/10.1093/molbev/msaf161
#evolbio #molbio #legionella
doi.org
Host-Specific Adaptation of Legionella pneumophila to Single and Multiple Hosts
Abstract. Legionella pneumophila is an endosymbiotic bacterial species able to infect and reproduce in various protist and human hosts. Upon entry into hum