iiinova — where your digital self keeps evolving

Ioanna Stefani @ioannastefani.bsky.social · 25/05/2026

Super excited for giving my 1st @pintofscience.uk talk last week, sharing my thrill about structural biology (especially cryo-EM) with a curious and engaging audience who made the experience memorable! Thanks to all @icr.ac.uk volunteers! 📸 of the event at the comments and 🔗 of the 📹 upon request 💬

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The Institute of Cancer Research @icr.ac.uk · 18/05/2026

🚨@pintofscience.uk begins today! We’re kicking off our Pint of Science events in the Prince Albert pub in Battersea. 🧬 Tonight’s sold-out event features ICR scientists @ioannastefani.bsky.social and Jessica Beecroft. #Pint26

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Pint of Science UK @pintofscience.uk · 07/05/2026

#pint26 is in less than 2 weeks! Discover the programme and book your tickets here 👉 pintofscience.co.uk 👈 🗓18-20 May 2026 📍45+ towns/cities across the UK 🗣Nearly 450 events

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Ioanna Stefani @ioannastefani.bsky.social · 26/03/2026

A much awaited research on how SNARE proteins enable highly specific fusion of vesicles with the corresponding compartment is now wrapped up in a beautiful preprint! Can’t wait to have a detailed read and use this information in cell biology applications !

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Matt Jessop @matthewjessop.bsky.social · 17/12/2025

An early Christmas present! The ICR’s new Hydra Bio FIB-SEM has been delivered, which will sit at the heart of a consortium between the @icr.ac.uk, Imperial, QMUL and KCL. Currently being stored at Imperial, it’ll be installed in a brand new lab at the ICR next year. Exciting things coming in 2026!🔬

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Nature Methods @natmethods.nature.com · 08/12/2025

Our Method of the Year 2025 is...drumroll please...EM-based connectomics!! Our Editorial introduces our choice and highlights six Comments and other related content in this special issue. Please join us in celebrating EM-based connectomics! 🎉🧠🔬 www.nature.com/articles/s41...

nature.com

Method of the Year 2025: electron microscopy-based connectomics - Nature Methods

A large network of interconnected neurons serves as the basis of brain function and of behavior. Methodological advances have enabled the reconstruction of large-scale and even whole-brain connectomes...

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Nature Portfolio @natureportfolio.nature.com · 26/11/2025

A paper in Nature shows that a 3.4-million-year-old partial foot found in Ethiopia in 2009 belongs to an ancient human relative named Australopithecus deyiremeda, a more primitive species of Australopithecus than the famous ‘Lucy’ (A. afarensis). go.nature.com/49BkCZY 🏺 🧪

The Burtele foot (left) and the foot embedded in an outline of a gorilla foot.
Image credit: Yohannes Haile-Selassie

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eLife @elife.bsky.social · 06/10/2025

High-resolution #CryoET provides ‘compelling’ evidence for the true 3D architecture of glutamatergic synapses: a complex ‘synaptoplasm’ rather than the textbook postsynaptic density. buff.ly/hOYKjHH

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Structural Biology @actacrystd.iucr.org · 02/10/2025

October issue is now available! journals.iucr.org/d/issues/202... The cover highlights the article on categorizing prediction modes within low-pLDDT regions of AlphaFold2 structures from the Richardson lab @duke-university.bsky.social : doi.org/10.1107/S205... Image credit: Chistopher Williams

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The Kavli Foundation @kavlifoundation.org · 29/09/2025

Many key cell structures are too thick for standard cryo-EM. Now in Nature Methods: Kavli-trained nanoscientist Yue Yu & colleagues describe a technique that boosts contrast 5x in thick biological samples, sharpening views of proteins, viruses & organelles. bit.ly/4mJPWJ1 #KavliNano #CryoEM

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Ioanna Stefani @ioannastefani.bsky.social · 16/09/2025

Had a superb week, full of great insights from cryo-ET experts and hands on workshops full of practical tips and advice! Many thanks to the incredible team of organisers, instructors and the lecturers who shared with us valuable knowledge! Thank you @diamondlightsource.bsky.social for hosting us!

linkedin.com

#cryoet #ebic #diamondlightsource | electron Bio-Imaging Centre (eBIC) at Diamond Light Source

🔗 We wrapped up our In Situ Cryo-ET Course last Friday at the electron Bio-Imaging Centre (eBIC) at Diamond Light Source, and it was a brilliant few days of learning and collaboration. Our on-site del...

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RCSB Protein Data Bank @rcsbpdb.bsky.social · 19/08/2025

How did a brain gene end up behaving like a virus? Research has shown that there is an evolutionary connection between Arc, retroviruses, and virus-like genetic elements called retrotransposons. More at Molecule of the Month: pdb101.rcsb.org/motm...

A comparison of the structures of dArc1 (capsid: 6TAP; pentamer: 6TAR), the retrovirus HIV (capsid: 3J3Q; pentamer: 7URN), and the retrotransposon Ty3 (6R24). Pentamers are shown in orange, and hexamers in yellow in the upper panel. In the lower panel, pentamers are shown with monomers colored in different shades of orange.

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Nature Portfolio @natureportfolio.nature.com · 20/05/2025

A study in Scientific Reports suggests that people living in democratic countries show higher benevolent and lower malevolent traits and higher levels of well-being. go.nature.com/4mmkukU 🧪

This is figure 2. Latent benevolent and malevolent trait means as a function of government type, (A, B) respectively, show citizens benevolent and malevolent latent means vary as a function of Economist Intelligence Unit (A) and Freedom House (B) national government specification. Autocratic latent means set to zero to statistically compare with other governments (A). Not Free governments latent means set to zero for comparison with Partially Free and Free government latent means (B).

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