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idvilchez.bsky.social

@idvilchez.bsky.social
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Jonathan Ryder, MD @jonathanrydermd.bsky.social · 22/01/2025
Case Report @thelancet.bsky.social ID Grand Rounds: Endocarditis of aortic/mitral valves and myocarditis due to syphilis! Discussion of cardiovascular syphilis history too Wasn't on my DDx for Cx neg IE! www.thelancet.com/journals/lan...
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idvilchez.bsky.social @idvilchez.bsky.social · 22/01/2025
late 60s no comorbodites, with P. aeruginosa left knee periprosthetic joint infection. Few years ago had first L knee PJI with P. aeruginosa treated with DAIR and 6 weeks cefepime. Seem like recurrent infection, what surgical approach would you consider
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Jonathan Ryder, MD @jonathanrydermd.bsky.social · 10/01/2025
New study in @cidjournal.bsky.social from France looking at molds (no yeast/dimorphics) found in blood cultures. n=80 isolates from 2012-2022 2/3rds were Fusarium, 10% Lomentospora, 5% Trichoderma, 5% Mucorales, 5% Aspergillus 70% Hematologic malignancies academic.oup.com/cid/advance-...
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idvilchez.bsky.social @idvilchez.bsky.social · 09/01/2025
do you think we should routinely test Enterobacterales for the presence of ESBL or just base or treatment on ceftriaxone Resistance? How would you treat this UTI with bacteremia (assuming is TMP-SMX qnd FQ resistant)
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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 09/01/2025
If you have a large volume of PD patients, and you don’t do this, you will see fungal peritonitis It’s a 1B from @ispd1.bsky.social www.nephjc.com/news/ispd202... I can’t imagine the replies which say you need not 🤦🏽‍♂️ Also came up on the pod: www.nephjc.com/freelyfilter...
Secondary Prevention

Guideline recommendations:

To prevent fungal peritonitis, we recommend that anti-fungal prophylaxis be co-prescribed whenever PD patients receive an antibiotic course, regardless of the indication for that antibiotic course (1B).

Even though this anti-fungal prophylaxis recommendation is unchanged from the 2016 ISPD guidelines, not all nephrologists apply this routinely.  Data to support this comes from a Cochrane meta-analysis including 2 randomized controlled studies on anti-fungal prophylaxis with oral nystatin or fluconazole showed a risk ratio of 0.28 (95% CI 0.12–0.63) for fungal peritonitis occurring after an antibiotic course (Lo et al, AJKD 1996; Restrepo et al, PDI 2010; Campbell et al, Cochrane Database Syst Rev 2017). However the evidence is based on just these 2 studies with relatively low GRADE due to high risk of bias in the old 1996 study and very few events in the other.
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idvilchez.bsky.social @idvilchez.bsky.social · 09/01/2025
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idvilchez.bsky.social @idvilchez.bsky.social · 09/01/2025
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Alan Koff @alankoff.bsky.social · 09/01/2025
I tend not to but understand if people do it. Once patients get fungal peritonitis the nephrologists tend to remove the catheter and put them on HD which can have a big impact on QoL.
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Alice Han @dralicehan.bsky.social · 09/01/2025
I really didn’t know heteroresistance in staph aureus was also a thing. But the lab is supposed to report as R if mec A gene found. pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov
Reversion From Methicillin Susceptibility to Methicillin Resistance in Staphylococcus aureus During Treatment of Bacteremia
Approximately 3% of Staphylococcus aureus strains that, according to results of conventional phenotypic methods, are highly susceptible to methicillin-like antibiotics also have polymerase chain react...
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idvilchez.bsky.social @idvilchez.bsky.social · 09/01/2025
how would you treat and ICD infection with lead and valvular vegetation that grew Staph aureus mecA gene positive per Biofire but Oxacillin susceptible per routine blood culture? Would you treat as MSSA with cefazolin or as MRSA with Vanco or Dapto ?
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Jonathan Ryder, MD @jonathanrydermd.bsky.social · 08/01/2025
Its imperfect data. But its some data and it suggests benefit. 5% absolute reduction in the RCT. I consider this to be a fairly low risk, high reward intervention. Short courses of fluc are generally well tolerated and there is evidence of benefit that's better than many things we do in ID
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Reposted by @idvilchez.bsky.social
Jonathan Ryder, MD @jonathanrydermd.bsky.social · 08/01/2025
I usually follow the kidney society guidelines for PD peritonitis, which does recommend it. There is some evidence to support its use, albeit not the highest quality: Cochrane Review: pmc.ncbi.nlm.nih.gov/articles/PMC... SR/MA: www.sciencedirect.com/science/arti...
sciencedirect.com
The efficacy of fluconazole for anti-fungal prophylaxis in peritoneal dialysis patients: A systematic review and meta-analysis
La eficacia de fluconazol como estrategia profiláctica en los pacientes con enfermedad renal crónica (ERC) sometidos a diálisis peritoneal (DP) con ex…
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idvilchez.bsky.social @idvilchez.bsky.social · 08/01/2025
if you have a patient with peritoneal dialysis catheter related peritonitis and you decide to treat with PO and/or intraperitoneal antibiotics, do you routinely recommend fluconazole prophylaxis?
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 02/12/2024
The Four Moments of Antibiotic Decision Making Random image #idsky #medsky #AMSsky
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Erin McCreary, PharmD @erinmccreary.bsky.social · 29/11/2024
🆕 #Breakpoints Episode: Drs. @annegretemartson.bsky.social, Megan Wimmer, and Evan Clemens join me to discuss all things (Val)ganciclovir!!! #idsky #pharmsky #amssky @sidpharm.bsky.social 🎧 sidp.pinecast.co
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 02/12/2024
"If you’re going to give antibiotics to patients who don’t need them, at least do the courtesy of giving them for a brief period of time." #IDQuotes @bradspellberg.bsky.social #idsky #medsky #AMSsky #utisky
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 29/11/2024
The ‘Big Five’ carbapenemases: 1️⃣VIM 2️⃣IMP 3️⃣NDM 4️⃣KPC 5️⃣OXA-48 🌟Timeline representing the introduction of carbapenems & the appearance of carbapenemases worldwide. 🌟 #idsky #medsky #microsky
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Ilan Schwartz @germhuntermd.bsky.social · 27/11/2024
Inaugural article in a new section in @cidjournal.bsky.social called “Clinical Dilemmas in Infectious Diseases” led by IDMedEd superstars Daniel Minter and Varun Phadke designed to teach clinical reasoning Rewriting the Script academic.oup.com/cid/advance-... #IDSky
academic.oup.com
Rewriting the Script
Natasha Spottiswoode, MD DPhil, Daniel J Minter, MD, Rachel Friedman-Moraco, MD; Rewriting the Script, Clinical Infectious Diseases, , ciae589, https://doi
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idvilchez.bsky.social @idvilchez.bsky.social · 27/11/2024
Harper's Bazaar, November 1933, by Romain de Tirtoff aka Erté
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Alice Han @dralicehan.bsky.social · 27/11/2024
#IDsky I’m currently going through my old twitter feed to find old posts I liked to find out who’s missing from 🦋 LBaddour Javier Villafuerte IDdocAdi Marc Scheetz German Esparza Jason Pogue Hemi Sulaiman Brad Spellberg Sumon Chakrabati Zain Chagla Jose Montoya Lance Burkhart Jake Scott Laura Marks
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Andre Kalil, MD MPH @drandrekalil.bsky.social · 27/11/2024
🆕🔥"Is Antibiotic De-Escalation Safe and Beneficial to Patients with Sepsis?" Our new article is out today: 👇 #IDSky #MedSky #PCCSky #ICUSky #emimcc #Ansky #EMSky #AMSSky #TxID #meded #Pharmsky #RXSky @unmc.bsky.social @unmccom.bsky.social ⬇️ bit.ly/4g7bGLE
bit.ly
Validate User
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Patrick Ching @patrickching.bsky.social · 27/11/2024
2025 CDC Adult Immunization Schedule 💉 www.cdc.gov/vaccines/hcp/imz-schedules/adult-age.html #VaccinesWork #IDSky #MedSky #immunization
2025 CDC Adult Immunization Schedule
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Aneesh K Mehta, MD, FIDSA, FAST @aneeshkmehta.bsky.social · 27/11/2024
Amazing news! HHS has determined that clinical research is no longer required for donors with HIV to donate their kidneys and livers for transplantation in the United States! Thank you to all the HOPE in Action teams and all the advocates for our patients! www.federalregister.gov/documents/20...
federalregister.gov
Organ Procurement and Transplantation: Implementation of the HIV Organ Policy Equity (HOPE) Act
The Department of Health and Human Services (HHS) amends the regulations implementing the National Organ Transplant Act of 1984, as amended (NOTA), to remove clinical research and institutional review...
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MGB Division of Infectious Diseases @mgb-id.bsky.social · 25/11/2024
pubmed.ncbi.nlm.nih.gov/39492946/
pubmed.ncbi.nlm.nih.gov
Associations of HIV and prevalent type 2 diabetes mellitus in the context of obesity in South Africa - PubMed
We found sex-specific differences in the relationship between adiposity and diabetes prevalence by HIV serostatus in South Africa. Notably, females living with obesity and HIV had lower prevalence of ...
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Steven Pergam, MD, MPH @pergamic.bsky.social · 18/11/2024
New virtual meeting for Immunocompromised Host Society: Addressing the Landscape of CMV Management in Transplant Recipients. Free to members or $25 plus a free membership for those not already members! Forward on to your residents, fellows, grad students, and international colleagues #TxID #CMV
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idvilchez.bsky.social @idvilchez.bsky.social · 27/11/2024
Marc Chagall - "La Tour Eiffel", 1910
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Alex Tatara, MD PhD @amtatara.bsky.social · 27/11/2024
Biomaterials friends, does anyone have recommendations for where to get PTFE molds made? I’m looking to make a set for ISO 5833.
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Steven Pergam, MD, MPH @pergamic.bsky.social · 26/11/2024
📢 Brand new ID faculty position just posted @fredhutch.bsky.social in Seattle. Join our ID group that studies infections in immunocompromised hosts. The Emerald city has great academics, phenomenal facilities, outstanding collaborators - all in amazing surroundings. apply.interfolio.com/159913
A photo of Fred Hutch Cancer Center in Seattle, with the Arnold buildling and "the Vessel" sculpture in front.Mount Rainer surrounded by a field of wildflowers
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idvilchez.bsky.social @idvilchez.bsky.social · 26/11/2024
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idvilchez.bsky.social @idvilchez.bsky.social · 26/11/2024
Tsuchiya Kôitsu, Snow on the Ukimido at Katada, 1934
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idvilchez.bsky.social @idvilchez.bsky.social · 26/11/2024
Miyamoto no Musashi Attacking the Giant Whale by Utagawa Kuniyoshi, 1847
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Anthony Cannella, MD, MSc, FACP, FIDSA @apcmd.bsky.social · 26/11/2024
Received my grant feedback from @niaidnews.bsky.social this week. Humbling to say the least, but not going to give up and push forward for a resubmission…because people with #NTMs need to have more research done in these infections. 😮
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idvilchez.bsky.social @idvilchez.bsky.social · 26/11/2024
Art by Guilherme Balbi Colors by Ren Spiller #xmen
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idvilchez.bsky.social @idvilchez.bsky.social · 26/11/2024
@dralicehan.bsky.social Toyohara Kunichika, A couple in Winter, 1875 - 1899 - youtu.be/Jz_qrQkpwN8?...
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idvilchez.bsky.social @idvilchez.bsky.social · 26/11/2024
@dralicehan.bsky.social
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 26/11/2024
The prolonged treatment recommended for nocardiosis does not rely on strong evidence!🆕️✨️Multi-center retrospective cohort study Shorter vs. standard-duration antibiotic therapy for nocardiosis #idsky #medsky link.springer.com/article/10.1...
link.springer.com
Shorter vs. standard-duration antibiotic therapy for nocardiosis: a multi-center retrospective cohort study - Infection
Purpose The prolonged treatment recommended for nocardiosis does not rely on strong evidence. Consequently, some clinicians opt shorter therapy in certain circumstances. We assessed the effectiveness ...
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Rossana Rosa @drrossanarosa.bsky.social · 09/11/2024
Infection Prevention People! I’m looking for you! IPSky #IPSKy IDSky #IDSky go.bsky.app/MdRkmpi
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Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 25/11/2024
Oral cephalosporins for pyelonephritis?! 🆕️⚡️⚡️COPY-ED Multicenter, retrospective study N=851 No difference in 14-day pyelonephritis treatment failure for oral cephalosporins* vs FQ/TMP-SMX for outpatient pyelonephritis in the ED #idsky #medsky * Mostly cephalexin www.sciencedirect.com/science/arti...
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Sustainabil-ID (www.sustainabil-id.com) @sustainabil-id.bsky.social · 26/11/2024
academic.oup.com/ofid/advance... Gave a read to this new article on #meded and #planetaryhealth. Couldn't find the lead authors here on bluesky. If you know please tag. Great job! #IDsky #climatechange
academic.oup.com
Medicine for a Changing Planet: Online Clinical Cases in Planetary Health and Infectious Diseases
Planetary health emphasizes the impact of environmental change on infectious diseases, yet integration of this concept into clinical medical education rema
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idvilchez.bsky.social @idvilchez.bsky.social · 26/11/2024
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idvilchez.bsky.social @idvilchez.bsky.social · 26/11/2024
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idvilchez.bsky.social @idvilchez.bsky.social · 26/11/2024
Vanity Fair Magazine Cover: February 1926 Artist: Anne Harriet Fish
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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · 26/11/2024
1. What ICD 10 code dominates your #IDSky life? @sebpoule.bsky.social @drtoddlee.bsky.social @absteward.bsky.social @idvilchez.bsky.social @idjclub.bsky.social @idiots-pod.bsky.social @dralicehan.bsky.social (for our international friends, there’s a “I” in there for a reason ;-) )
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idvilchez.bsky.social @idvilchez.bsky.social · 26/11/2024
Willi's Wine Bar (1935) by A.M. Cassandre
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Joseph Marcus @josephmarcusid.medsky.social · 26/11/2024
First autochthonous transmission of dengue 🦟 in 2024 just reported in Texas 102 travel related cases 1 death Most cases since 2002 #IDSky dshs.state.tx.us/news-alerts/...
dshs.state.tx.us
Texas public health officials announce first locally acquired case of dengue virus in 2024 | Texas DSHS
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idvilchez.bsky.social @idvilchez.bsky.social · 26/11/2024
pubmed.ncbi.nlm.nih.gov/39365895/ fish skin graft? First time I hear about this...
pubmed.ncbi.nlm.nih.gov
Intact Fish Skin Graft to Treat Deep Diabetic Foot Ulcers - PubMed
Among patients with deep diabetic foot ulcers, treatment with intact fish skin graft was superior to standard of care in proportion of wounds healed at 16 weeks and was associated with faster time to ...
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MicheleMuse 💙🌈🦋🇺🇦 @michelemuse.bsky.social · 26/11/2024
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Alice Han @dralicehan.bsky.social · 26/11/2024
#IDsky Bless the participants who decided to take part in this study and be subjected to 100s of 🦟 bites 🧵 www.nejm.org/doi/full/10....
nejm.org
Safety and Efficacy of Immunization with a Late-Liver-Stage Attenuated Malaria Parasite | NEJM
Currently licensed and approved malaria subunit vaccines provide modest, short-lived protection against malaria. Immunization with live-attenuated Plasmodium falciparum malaria parasites is an alte...
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Alice Han @dralicehan.bsky.social · 26/11/2024
Maybe the patient was on rifaximin given liver failure for PSC, s/p SOT @steventong.bsky.social #IDSky 👇 www.nature.com/articles/s41...
nature.com
Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin - Nature
Rifaximin use, particularly in patients with liver cirrhosis, may be compromising the clinical use of daptomycin.
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idvilchez.bsky.social @idvilchez.bsky.social · 26/11/2024
George Barbier 🇫🇷 (1882-1932) " L'Hiver " (Winter) , 1925
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