The T7 bacteriophage deactivates bacterial defence systems through T7K phosphorylation of nearly all host and phage proteins during infection.

Direct recognition of viral proteins is key to bacterial immunity. Here, Evans et al. uncover the mechanisms used by two distinct defense proteins to detect the phage DNA packaging motor mechanisms: b...

Recognition of foreign molecules inside cells is critical for immunity in all domains of life. Proteins of the STAND NTPase superfamily, including eukaryotic nucleotide-binding oligomerization domain ...