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Hiscock Lab

@hiscocklab.bsky.social
453 followers 861 following 6 posts

Heart of a developmental biologist, head of a mathematician/physicist. Posts from Tom and lab members. twhiscock.github.io

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Hiscock Lab @hiscocklab.bsky.social · 25/05/2026
🚨Job alert in theory/math devbio 🚨 I’m currently advertising postdoc positions to join my group. We’re building reaction-diffusion models to understand some of the amazing things embryos can do. We are based in a beautiful part of Scotland! Please share! www.abdn.ac.uk/jobs/vacanci...
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Hiscock Lab @hiscocklab.bsky.social · 25/03/2026
New paper from the lab out now in Development @dev-journal.bsky.social, led by the wonderful (Dr!) Daniel Muzatko. We re-examined activator-inhibitor mechanisms of symmetry breaking (aka Turing patterns) and found some surprising things! doi.org/10.1242/dev.....
doi.org
Fundamental limits on symmetry breaking by Turing-like activator-inhibitor mechanisms
Summary: In silico analysis of complex reaction-diffusion mechanisms reveals fundamental limits on the ability of activator-inhibitor systems to break symmetry in vivo.
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Reposted by Hiscock Lab
canaztekin.bsky.social @canaztekin.bsky.social · 21/10/2025
🔬 Limb regeneration depends on regenerative signaling center cells — but how do these cells influence others to proliferate, migrate, or differentiate? We’re recruiting PhD or Postdoc candidates to explore this with our collaborator @osvaldo-chara.bsky.social !
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Reposted by Hiscock Lab
Zena Hadjivasiliou @zenahadjivasiliou.bsky.social · 16/09/2025
Fresh from the press💥 We asked what happens when you evolve gene regulatory networks computationally at scale. Do general principles of GRN evolution jump out? Is the process predictable? Read on to find out @prxlife.bsky.social @crick.ac.uk @ucl-ipls.bsky.social 👉 journals.aps.org/prxlife/abst...
journals.aps.org
Gene Network Organization, Mutation, and Selection Collectively Drive Developmental Pattern Evolvability and Predictability
The historical order in which mutations appear during evolution determine the evolutionary trajectory of gene regulatory networks and influence how developmental patterns change and diversify over tim...
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Jan Rombouts @janrombouts.bsky.social · 18/09/2025
Please allow me to introduce... our new preprint 🎉 Together with Michael Zhao, Anna Erzberger and Alexander Aulehla, we investigate pattern formation due to aggregation in confined systems. You can find it at arxiv.org/abs/2509.08533 @michaelzhao.bsky.social @erzbergerlab.bsky.social
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Hiscock Lab @hiscocklab.bsky.social · 27/06/2025
🚨Job alert in theory/math devbio 🚨 I’m currently advertising postdoc positions to join my group. We’re building reaction-diffusion models to understand some of the crazy things embryos can do. We are based in a beautiful part of Scotland :). Please share! www.abdnjobs.co.uk/vacancy/rese...
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Hiscock Lab @hiscocklab.bsky.social · 02/06/2025
PS The lead author, Daniel Muzatko, is currently on the postdoc job market so please get in touch if you are looking for a stellar new postdoc! PPS The Hiscock Lab is still actively hiring embryo-curious theoreticians of all types, see here for opportunities: twhiscock.github.io
twhiscock.github.io
Hiscock LabHiscock Lab
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Hiscock Lab @hiscocklab.bsky.social · 02/06/2025
Along the way, we developed a freely available Julia package that allows complex reaction-diffusion PDEs to be analysed quickly (millions of parameter sets per minute) and easily (in just a few lines of intuitive code!). Check it out here: github.com/hiscocklab/R...
github.com
GitHub - hiscocklab/ReactionDiffusion.jl
Contribute to hiscocklab/ReactionDiffusion.jl development by creating an account on GitHub.
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Hiscock Lab @hiscocklab.bsky.social · 02/06/2025
🚨 theory/math devbio preprint alert!!! 🚨 Led by my v. talented PhD student, Daniel Muzatko, we’ve found some rather general and intriguing constraints on reaction-diffusion systems that allow them to self-organize developmental patterns: www.biorxiv.org/content/10.1...
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Hallou Lab @halloulab.bsky.social · 17/03/2025
🚨 Paper Alert 🚨 Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!! www.nature.com/articles/s41...
nature.com
A computational pipeline for spatial mechano-transcriptomics - Nature Methods
The authors present a computational framework that leverages mechanical force inference and spatial transcriptomics to enable analyses of the interplay between the transcriptomic and mechanical state.
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Reposted by Hiscock Lab
Berta Verd @bertaverd.bsky.social · 05/02/2025
I am recruiting an #ERC funded PostDoc to work on the evolution of vertebral counts in cichlids. This is an experimental project & will be looking for candidates with experience generating reporter lines, live-imaging and experimental embryology. Application deadline: 25th Feb. tinyurl.com/33jbu8fa
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