Mandimycin, a polyene macrolide, exhibits strong antifungal activity and possesses a mode of action that is distinct from other compounds of this class.

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Background : Nakaseomyces glabratus (Candida gabrata) poses a significant clinical challenge due to common drug resistance. We report a case of a complicated urinary tract infection (UTI) progressing ...

npj Antimicrobials and Resistance - Unlocking the potential of experimental evolution to study drug resistance in pathogenic fungi

npj Antimicrobials and Resistance - Unlocking the potential of experimental evolution to study drug resistance in pathogenic fungi

Collateral-sensitivity-based drug cycling effectively prevents and impedes the evolution of antifungal drug resistance in Candida auris.