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Greg Madej

@greg-madej.bsky.social
99 followers 172 following 32 posts

University of Regensburg | #cryoEM | #membrane #proteins

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Greg Madej @greg-madej.bsky.social · 05/07/2026
Inspiring days in Sutton Bonington with Hydrosensing team. Great discussions, slightly too much fancy food, and a Saturday run that turned into an obstacle course, dodging cars that all drive on the wrong side of the road. Great collaborators becoming even better friends. @hydrosensing.bsky.social
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Greg Madej @greg-madej.bsky.social · 12/06/2026
Great to host my dear friend Uli Zachariae in Regensburg today. It’s always inspiring how much common ground exists between computational electrophysiology and cryo-EM: different methods, same questions about how proteins move, function, and shape life. #StructuralBiology #CryoEM #IonChannels
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Greg Madej @greg-madej.bsky.social · 18/03/2026
While visiting Regensburg, Ellie had a confidential side project: using a scoring pipeline for flavour, texture, and appearance, she identified top performers with the kind of confidence usually reserved for structure papers. Reviewer 2 has requested a larger sample size and more ice cream controls.
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Greg Madej @greg-madej.bsky.social · 26/10/2025
Well, I finally swapped the predictable pavement for some unpredictable trail running, and let's say my legs have feelings now—mostly bewilderment and slight betrayal. I'm back home, covered in dirt, slightly bruised. Most importantly, I didn't need to call for a helicopter. Success!
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Ziegler lab UR @ziegler-lab-ur.bsky.social · 26/10/2025
Nanocosmos: Faster Than Your Quickest Thought! "Physik goes Downtown Night 2025" featured science presented by speakers from RUN that was truly mind-blowing. They delivered fantastic talks about the movement of atoms at speeds that completely redefine "quick"! www.uni-regensburg.de/physik/schul...
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Greg Madej @greg-madej.bsky.social · 14/10/2025
The @ziegler-lab-ur.bsky.social delegation survived the Munich Half Marathon! This Trial of Spirit demanded the Force be strong with us. And the Force was extraordinarily strong with @katjaurbansky.bsky.social Her exceptional pace has earned her a promotion to the Council of cryoKnights - so cool!
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ERC SYNERGY Project HYDROSENSING @hydrosensing.bsky.social · 07/10/2025
Enjoy the picture to see moments from the visit — from the Robin Hood statue to the lab and evening strolls through Nottingham! 🌿 @uniregensburg.bsky.social 4/4
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ERC SYNERGY Project HYDROSENSING @hydrosensing.bsky.social · 07/10/2025
The visit highlighted the spirit of our project: connecting scientists across borders and disciplines to advance cutting-edge research together to uncover the mechanisms plants use to perceive water stress. 3/4
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ERC SYNERGY Project HYDROSENSING @hydrosensing.bsky.social · 07/10/2025
During this visit, Christine Ziegler @ziegler-lab-ur.bsky.social joined Malcolm Bennett in their lab at the University of Nottingham, while Eilon Shani @eilonshani.bsky.social also happened to be visiting the same research center — a perfect coincidence for a productive and friendly reunion! 2/4
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Greg Madej @greg-madej.bsky.social · 09/10/2025
I've just commissioned a cryoEM new coffee mug in new design. To be fair, the mug is arguably the more critical piece of equipment for data collection. You try imaging a membrane proteins at 5 AM without caffeine. ☕🔬#cryoEM
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Greg Madej @greg-madej.bsky.social · 04/09/2025
MC 2025: We came, we saw, we won🏆 🏆! Amazing team on a fantastic time at the Microscopy Conference in Karlsruhe. Get this: two of our posters won Poster Prizes! We're pretty sure it was our perfect blend of science and questionable doodles in the margins. @ziegler-lab-ur.bsky.social
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Greg Madej @greg-madej.bsky.social · 17/07/2025
Ultrafast Almost Gold! The Regensburg Center for Ultrafast Nanoscopy bio-section took second in the relay! Physics' reaction rates are attoseconds, but ours, Slower. Probably why "The Quantum Leapers" edged us out. Great fun and pretzels! @ziegler-lab-ur.bsky.social @katjaurbansky.bsky.social
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Greg Madej @greg-madej.bsky.social · 26/06/2025
So exciting … The publication where I had the privilege to contribute has been selected as an Editor's Choice. This recognition truly reflects everyone's hard work and dedication.
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ERC SYNERGY Project HYDROSENSING @hydrosensing.bsky.social · 12/06/2025
Recently, our early-career researchers agreed on the value of organizing regular sessions for PhDs and PostDocs to explore key research topics in greater depth. These sessions offer a space to understand the methods & techniques used across the 4 #Hydrosensing teams. #science
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ERC SYNERGY Project HYDROSENSING @hydrosensing.bsky.social · 12/06/2025
In the very 1st session this Tuesday, @greg-madej.bsky.social, from @uniregensburg.bsky.social @ziegler-lab-ur.bsky.social, presented how their expertise is applied within the project; specially the use of Cryo-EM in the study of membrane-embedded proteins. 🌐 www.uni-regensburg.de/biologie-vor...
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Greg Madej @greg-madej.bsky.social · 02/06/2025
Yesterday, through the tireless work of training runs, the support of my team, and the simple act of putting one foot in front of the other, we reached the finish line. The justice of completing what we set out to do, after the planning and the effort, has been served. @katjaurbansky.bsky.social
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Greg Madej @greg-madej.bsky.social · 27/05/2025
academic.oup.com/nar/article/... Proud to have been a small part of the team behind the latest publication. It was a privilege to collaborate with such a talented group of researchers on this work. A massive congratulations to all the authors for this contribution to the field! #RNA #cryoEM
academic.oup.com
A conserved nuclease facilitates environmental DNA uptake
Abstract. Bacteria acquire new traits through the uptake of genetic material from the environment, a process requiring DNA processing. However, the molecul
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Greg Madej @greg-madej.bsky.social · 12/05/2025
Here is an update on our recent activity.. febs.onlinelibrary.wiley.com/doi/10.1002/...
febs.onlinelibrary.wiley.com
FEBS Press
Mutations in polycystin-1 (PC1) or polycystin-2 (PC2) cause autosomal-dominant polycystic kidney disease (ADPKD). We generated a novel gain-of-function PC2/PC1 heteromeric ion channel by mutating por...
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ERC SYNERGY Project HYDROSENSING @hydrosensing.bsky.social · 22/04/2025
In @uniofnottingham.bsky.social ERC Hydrosensing members spent a few intense (and wardrobe-consistent 😅) days filming about research on root systems and how plants adapt to drought. More footage for the documentary is being filmed at locations around the world in the coming year.
Malcolm Bennet in the greenhouse with the filming crewPoonam Mehra while filmingMalcolm Bennet in the greenhouse while filming
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Ziegler lab UR @ziegler-lab-ur.bsky.social · 22/04/2025
We had the pleasure to contribute to this publication... It was a pleasure to be part of this effort. Congratulations to all authors! #cryoEM @cmziegler.bsky.social @greg-madej.bsky.social pubs.acs.org/doi/full/10....
pubs.acs.org
Retinal to Retinal Energy Transfer in a Bistable Microbial Rhodopsin Dimer
Neorhodopsin (NeoR) is a newly discovered fungal bistable rhodopsin that reversibly photoswitches between UV- and near-IR absorbing states denoted NeoR367 and NeoR690, respectively. NeoR367 represents...
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Greg Madej @greg-madej.bsky.social · 17/04/2025
These were great days.. thank you all! @hamannlab.bsky.social @eilonshani.bsky.social @sara-morghen.bsky.social @francesco-saffioti.bsky.social @katjaurbansky.bsky.social @wiebkehaeger.bsky.social @michaelaticha.bsky.social @hydrosensing.bsky.social @hydrophotonics.bsky.social
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Denis Chrétien @dchretien.bsky.social · 17/04/2025
First images coming soon 🤩
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Greg Madej @greg-madej.bsky.social · 15/04/2025
#HydroSensing Synergy Group - your fascinating talks last week completely watered the seeds of curiosity in my brain 😉. Prepare to see the photographic evidence of my descent into macroscale hydrosensing madness! I'm pretty sure my leafy friends 🌱 are judging my overly enthusiastic note-taking.
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Greg Madej @greg-madej.bsky.social · 14/04/2025
We are fascinated by how our leafy friends 🌱 feel the subtle shifts in soil moisture 💦 Last week we hydrated your minds and cultivated connections at our #erc meeting focusing on the captivating world of #Plant #HydroSensing 🧩@hydrosensing.bsky.social @hydrophotonics.bsky.social
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Hamannlab @hamannlab.bsky.social · 11/04/2025
Exciting ERC synergy project meeting in Regensburg 😊@hydrosensing.bsky.social @ntnudiscovery.bsky.social @uniofnottingham.bsky.social @uniregensburg.bsky.social
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Greg Madej @greg-madej.bsky.social · 13/04/2025
After our annual #HydroSensing meeting in Regensburg, we went for a hike.. of course with a subsequent data collection and data processing demonstration 😁 #Plant #cryoEM
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Greg Madej @greg-madej.bsky.social · 03/03/2025
the cryo-clipping-box for JEOL cryoARM... easy! #cryoEM
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Greg Madej @greg-madej.bsky.social · 01/03/2025
We've been using SerialEM 4.2.0 beta on our JEOL cryoARM-200 for a while now. The multi-record setup and coma vs. IS calibration routines are particularly helpful – they're user-friendly and consistently reliable. #cryoEM #SerialEM
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Greg Madej @greg-madej.bsky.social · 28/02/2025
Just another Friday evening cryoEM screening.. with pizza 😁 #cryoEM
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AlphaFold Unofficial @alphafold.bsky.social · 23/02/2025
“LeCun, who earned his bachelor's and Ph.D. in France , said the changes in the United States should be a wake-up call for European institutions and companies. "You may have an opportunity to attract some of the best scientists in the world," he wrote.” www.businessinsider.com/meta-yann-le...
businessinsider.com
Meta's chief AI scientist says US-based researchers may look abroad as Trump tries to freeze funding
Meta's Yann LeCun warned there could be an exodus of US-based scientists due to Trump's funding cuts.
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Greg Madej @greg-madej.bsky.social · 20/02/2025
„Jugend Forscht 2025” the German outreach - it’s the youth science competition aiming to interest young scholars in science - this year also #cryoEM
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Bjørn Panyella Pedersen @bjornppedersen.bsky.social · 20/02/2025
⭐8 days left to apply for 👇 postdoc position ⭐ and join an international group of great people😊
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Marcel Dickmanns | 🌿❄️🔬 @madic.bsky.social · 19/02/2025
Our methods paper made it to bioRxiv: doi.org/10.1101/2025... Full #cryoET workflows for #plant tissues. Plus some general tricks and tweaks on serial Lift-Out and cryo-FLM. 🧪🧵1/5 #teamtomo #PlantScience #Physcomitrium #Arabidopsis #cryoEM #CLEM
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Greg Madej @greg-madej.bsky.social · 19/02/2025
temperature-controlled dewar from NanoSoft Materials (www.nanosoftmaterials.com). We are using it - no solidified ethane! Plus: if you happen to drop a grid in the brass cup the groove design on the bottom makes retrieval easy. Highly recommend. #cryoem #vitrification #microscopy #vitrobot
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Greg Madej @greg-madej.bsky.social · 14/02/2025
Welcome to the jungle, we got fun and games We got everything you want, honey, we know all the names.. www.wobblylabs.com/quantum-jungle
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Greg Madej @greg-madej.bsky.social · 13/02/2025
Mystery 2D class... friendly panda or grumpy fish? #cryoEM
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ERC SYNERGY Project HYDROSENSING @hydrosensing.bsky.social · 13/02/2025
📸 RIGHT: A tissue culture plate of tomato; one step in our journey to understanding plant resilience 🍅 📸 LEFT: Screening different CRISPR libraries in tomato tissue culture—hunting for key genes in sensing water and water stresses 🧬 3/3
A tissue culture plate of tomatoScreening different CRISPR libraries in tomato tissue culture
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ERC SYNERGY Project HYDROSENSING @hydrosensing.bsky.social · 10/02/2025
Meet the #HydroSensing team from Regensburg! 🔬 From braving the cold room to battling centrifuges, our team tackles science with passion, precision, and just a little bit of chaos. Follow along as we take you behind the scenes! 👇 #ScienceLife #LabAdventures 1/8
media.tenor.com
a man wearing a beanie and a black jacket is smiling and holding a piece of food .
ALT: a man wearing a beanie and a black jacket is smiling and holding a piece of food .
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Dr Mark D. Scherz @markscherz.bsky.social · 10/02/2025
✨We are hiring!✨🧪🏛️🧬 The @nhmdk.bsky.social at the University of Copenhagen is seeking a permanent, full-time Molecular Biology Lab Manager to help us establish and run our National Facility for #Museomics in the heart of one of Europe's most beautiful cities! Please reskeet!
candidate.hr-manager.net
Full-time Molecular Biology Lab Manager at Natural History Museum Denmark
Natural History Museum Denmark, Faculty of Science, the University of Copenhagen is looking for a full-time Molecular Biology Lab Manager, to start 1st June 202
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Greg Madej @greg-madej.bsky.social · 11/02/2025
Mystery Protein Challenge Calling all structural biology enthusiasts and #cryoEM aficionados! Can you identify the protein shrouded in this 2D class average? Hint: This protein plays a vital role in the respiratory chain.
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