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Organic & Biomolecular Chemistry

@orgbiomolchem.rsc.org
582 followers 222 following 539 posts

Rapid publication of organic synthesis, physical organic, chemical biology and supramolecular chemistry research. Published by @rsc.org 🌐 Website: rsc.li/orgbiomolchem

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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 9h
📢Our latest issue is now online! 🔓Check out the #OpenAccess paper behind the cover by Artur Kasprzak & co. from Warsaw University of Technology & Medical University of Warsaw obtaining covalent and non-covalent conjugates of bowl-shaped sumanene and 5-fluorouracil #orgchem doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 29/09/2026
🔓Be sure to read in our latest issue #OpenAccess research from Joseph B. Sweeney & Julien Doulcet @lancasteruni.bsky.social using an aryne–arylamine–aldehyde three-component reaction for the synthesis of drug-like 2-aminobenzyl ethers #orgchem #medchem Find in full below🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 28/09/2026
Don't miss this review in our latest issue from @kanvah.bsky.social et al. at IIT Gandhinagar highlighting the evolution of chemical biology approaches for detecting and profiling protein citrullination #orgchem #chembio Check it out on our website👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 27/09/2026
🔓Check out a #OpenAccess paper by Alison Thompson & co. @dalhousie.bsky.social in our latest issue developing a new nitrosylation reaction for pyrroles, featuring tert-butyl nitrite as a mild nitrosylation agent #orgchem Read the full article here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 26/09/2026
Take a look in our latest issue at a paper by Xiaoqiang Yu et al. using 9-fluorenone as a photosensitizer for nickel-catalyzed reductive cross-coupling of aryl halides with alkyl iodides #orgchem 📍Dalian University of Technology doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 25/09/2026
🔓Be sure to read #OpenAccess research from Haruki Mizoguchi, Akira Sakakura & co. at Okayama University in our latest issue reporting the stereoselective synthesis of β,β-diborylalanine and its incorporation into oligopeptides #orgchem Find it in full below👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 24/09/2026
🔓Don't miss this #OpenAccess paper in our latest issue by Stéphane Le Calvé, Mourad Elhabiri et al. @unistra.fr describing the hemisynthesis of ribazole-2′,3′-cyclophosphate #natprod #orgchem Check it out in full on our website🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 23/09/2026
📢Our latest issue is online! Check out the cover article by Nasir Rasool, @sumbal6s.bsky.social, @jamal7r.bsky.social & co. at Government College University Faisalabad & @labso.bsky.social reviewing recent advances in titanium-mediated organic transformations #orgchem doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 22/09/2026
Read a paper by Srihari Pabbaraja, Goverdhan Mehta et al. at CSIR-IICT & University of Hyderabad in our latest issue describing a transition-metal-free cascade approach to indoloindolizines for the synthesis of bioactive homofascaplysin C analogues #orgchem Find it below🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 21/09/2026
🔓Don't miss this #OpenAccess review in our latest issue from Herman O. Sintim & co. @notredame.bsky.social revisiting multicomponent Doebner and Povarov quinoline synthesis for modern-day drug-discovery #orgchem #medchem Check out the full article here👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 20/09/2026
Check out this paper by Yulai Hu et al. from Northwest Normal University in our latest issue on visible-light-induced radical fluoroalkylation/cyclization for the synthesis of 2-fluoroalkyl-3-aminoindoles via an EDA complex #orgchem Read it in full below🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 19/09/2026
Take a look in our latest issue at research from Badrodin Ayyub Shaikh reporting a SmI2-mediated tandem cyclization route for stereoselective synthesis of the tetracyclic core of daphenylline #orgchem 📍IISc Bangalore doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 18/09/2026
🔓Be sure to read this #OpenAccess paper from Pavel Lhoták & co. at UCT Prague in our latest issue studying the conformational preferences and dynamic behavior of 2-monothiacalix[4]arene #orgchem Find the full report on our website👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 17/09/2026
Don't miss this paper in our latest issue from Wenling Qin, Zhen Wang et al. at Chongqing University describing the asymmetric synthesis of fused seven-membered chromanones from 3-hydroxy chromones and vinyl ethylene carbonates #orgchem Check it out in full here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 16/09/2026
📢Our latest issue is now online! 🔓Check out the #OpenAccess review behind the cover by Harshita Kumari & co. from the University of Cincinnati discussing macrocycle-mediated modulation and repurposing of antibacterial and non-antibacterial drugs #orgchem #medchem doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 15/09/2026
🔓Take a look at a #OpenAccess paper from Francesca Cardano, Marco Blangetti, Andrea Fin & co. in our latest issue on the structural and photophysical evaluation of O-alkoxy-substituted BODIPY dyes in liposomes #orgchem 📍Universita di Torino doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 14/09/2026
Don't miss in our latest issue this review by Zhong-Wei Hou, Lei Wang et al. from Taizhou University summarising the latest advancements in utilizing 9,10-phenanthrenequinone as a versatile catalyst for organic reactions #orgchem Check out their full article here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 11/09/2026
🔓Be sure to read this #OpenAccess paper from @emmertlab.bsky.social, Ozgur Yilmaz & co. at Mersin University & Merck & Co. in our latest issue describing a general, operationally simple N-dealkylation of simple and complex tertiary amines #orgchem Find it here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 10/09/2026
Don't miss this review in our latest issue covering the recent trends in synthetic approaches to α-amino ketones by Mariusz Zalewski & Sebastian Stecko from the Institute of Organic Chemistry, Polish Academy of Sciences #orgchem Check it out in full below👇 doi.org/10.1039/d6ob...
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Reposted by Organic & Biomolecular Chemistry
Natural Product Reports @natprodreports.rsc.org · 09/09/2026
We are delighted to announce that Professor Dong-Chan Oh (Seoul National University) has been appointed as our new Editorial Board Chair! Please join us in welcoming Dong-Chan to his new position🎉#secmet #chemsky Find out more about Dong-Chan and his appointment here🔽 blogs.rsc.org/np/2026/09/0...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 09/09/2026
Check out this paper from Samik Nanda et al. at IIT Kharagpur in our latest issue describing a chemoenzymatic approach to towards naturally occurring macrolactams melearorides A and B #orgchem #natprod Read their full report on our website🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 08/09/2026
🔓Take a look in our latest issue at this #OpenAccess paper from Jolene P. Reid, Michael O. Wolf & co. investigating the photophysics of click-functionalized 2,2′-bithienyl flexible Lewis pairs #orgchem #compchem 📍 @science.ubc.ca doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 07/09/2026
🔓Be sure to read this #OpenAccess paper by Omar Boutureira, Yolanda Díaz, M. Isabel Matheu et al. from @urv.cat in our latest issue describing stereoselective access to allenic sphingosine analogues as SphK inhibitors #orgchem #medchem Find it in full on our website👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 04/09/2026
Don't miss this review in our latest issue by Prodeep Phukan et al. from Gauhati University looking at the recent advances in sulfonyl guanidine synthesis #orgchem Check it out in full here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 03/09/2026
📢Our latest issue is now online! 🔓Check out the #OpenAccess paper behind the cover from @knipechem.bsky.social, Sam Thompson & co. @unisouthampton.bsky.social & @ox.ac.uk reporting water-soluble β-strand peptidomimetics #orgchem doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 01/09/2026
🔓Be sure to read in our latest issue #OpenAccess research from Thomas Wirth & co. @cardiffuni.bsky.social describing the continuous flow electrochemical oxidation of activated methylarenes using O2 #orgchem Find their full report on our website🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 31/08/2026
Don't miss a paper, part of our collection celebrating the 65th birthdays of Jay Siegel & Kim Baldridge, by Ho Yu Au-Yeung et al. at the University of Hong Kong investigating the interplay of ring size, rigidity & curvature in catenane complexes #orgchem Check it out here👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 30/08/2026
Check out this review from Ahmed Khalil at King Faisal University in our latest issue summarising synthetic strategies, photophysical properties and biomedical applications of phthalocyanine conjugated nucleosides #orgchem Read it in full below🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 29/08/2026
Take a look at research in our latest issue from Santosh B. Mhaske & co. reporting the organocatalytic stereoselective synthesis of amino acid-fused quinazolinone based triazacyclic frameworks #orgchem 📍CSIR-NCL doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 28/08/2026
Be sure to read a paper by Rodrigo O. M. A. de Souza, Rodolfo G. Fiorot et al. from Universidade Federal Fluminense in our latest issue describing the regioselective acid-catalyzed conversion of cannabidiol into THC isomers #orgchem Find the full article on our website👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 27/08/2026
🔓Don't miss this #OpenAccess paper in our latest issue from @myanificent.bsky.social, @drmichaeljhallchem.bsky.social & co. @newcastleuni.bsky.social describing improved aromatic Finkelstein reactions for the synthesis of iodinated BODIPYs #orgchem Check it out in full here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 26/08/2026
📢Our latest issue is online! The cover is from the Editorial of our joint themed collection with @orgchemfront.rsc.org celebrating the 65th birthdays of Jay Siegel & Kim Baldridge, guest edited by @jessenlab.bsky.social, Mihaiela Stuparu & @chemguyeli.bsky.social #chemsky doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 25/08/2026
Read this paper from Liangyong Mei & co. at the University of North Florida in our latest issue describing the synthesis of CF3-containing dihydropyrido[1,2-a]indolones via a visible-light-promoted radical cascade [4+2]/[4+2] cycloaddition #orgchem Find it in full🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 24/08/2026
🔓Don't miss #OpenAccess research in our latest issue from Lukas J. Gooßen et al. @ruhr-uni-bochum.de reporting a trifluoroacetate-derived reagent for trifluoromethylation of (hetero)arenes #orgchem Check it out in full here👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 23/08/2026
Check out this review by Youpeng Zuo, Pengfei Zuo & co. from Suzhou University in our latest issue focused on the recent advances in directing group rearrangement strategies in transition-metal-catalyzed C–H activation #orgchem Find the full article below🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 22/08/2026
Take a look in our latest issue at research from Santhosh Sreelekshmi & Krishna P. Kaliappan describing a unified strategy to the enantiomers of atractylenolides and related eudesmane sesquiterpenoids from (−)-verbenone #orgchem #natprod 📍IIT Bombay doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 21/08/2026
Be sure to read research by Marco Lessi, Antonio Del Vecchio & co. from the University of Pisa in our latest issue reporting a simplified protocol for the electroreduction of nitroarenes #orgchem Find their full report on our website👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 20/08/2026
Don't miss this review in our latest issue from Ju Wu et al. at Ningbo University looking at the recent advances in electrochemical synthesis of phosphorylated organic compounds from P–H reagents #orgchem Check it out in full here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 19/08/2026
📢Our latest issue is now online! Check out the research behind the cover by Masahiro Ikejiri & co. from Osaka Ohtani University utilising a trifluoromethyl analog of the green fluorescent protein chromophore for reversible fluorescence OFF/ON switching #orgchem doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 18/08/2026
Be sure to read this review in our latest issue by Ajit Kumar Mahapatra et al. from IIEST Shibpur summarising recent progress in chemodosimeter-based fluorescent probes for esterase, nitroreductase and tyrosinase #orgchem Find the full article below👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 17/08/2026
🔓Don't miss this #OpenAccess research from Massimo Giammarco & Yuri Bolshan @ontariotechu.bsky.social in our latest issue on the synthesis of C,N-glycosides from exo-glycals via selective N2-1,2,3-triazole and N1-pyrazole alkylation #orgchem Check it out on our website🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 16/08/2026
Check out in our latest issue a paper by Gert von Helden, Alessandro Rodrigues, Thiago C. Correra & co. @fhi-mpg.bsky.social & @uspoficial.bsky.social probing aminopalladation mechanistic pluralism by helium nanodroplet ion spectroscopy #orgchem Read in full here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 15/08/2026
Take a look at this review by Sunmin Jiang, Tao Shen et al. in our latest issue covering the recent advances in electroreductive dearomatization of aromatic compounds #orgchem 📍Shanghai Jiao Tong University & Wuhan University doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 14/08/2026
Be sure to read research in our latest issue from Masahiko Isaka, Hidetoshi Tokuyama & co. at NSTDA & Tohoku University describing the chemoselective derivatization of the potent antimalarial fungal metabolite 9-methoxystrobilurin G #orgchem Find it in full below👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 13/08/2026
🔓Don't miss this #OpenAccess paper by Bram B. C. Peters, Ben L. Feringa et al. @feringalab.bsky.social @rug.nl in our latest issue reporting a self-propagating Pudovik reaction using phosphonic acid-based catalysts #orgchem Check out the full article on our website🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 12/08/2026
📢Our latest issue is now online! Check out the paper behind the cover by Ajaya Ram Shrestha & co. at Luxna Biotech & University of Osaka describing an improved guanidine protecting group for the efficient synthesis of GuNA[t-Bu]-modified antisense oligonucleotides #orgchem doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 11/08/2026
Be sure to read research from Kaushik Ghosh et al. at IIT Roorkee in our latest issue describing metal–ligand cooperative Ni(ii) catalysis for one-pot access to biologically relevant quinolines and their transfer hydrogenation #orgchem Find in full on our website🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 10/08/2026
🔓Don't miss this #OpenAccess paper in our latest issue by Ewa Żymańczyk-Duda, Rafał Kowalczyk & co. at Wrocław University of Science & Technology on a highly efficient and enantioselective bioreduction of 4-phenyl-6,7-dihydrothieno[3,2-c]pyridine #orgchem Check it out here👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 08/08/2026
Take a look in our latest issue at a paper by Teodoro S. Kaufman, Andrea B. J. Bracca et al. reporting the total syntheses of acremines D, E and N from a single precursor #natprod #orgchem 📍Universidad Nacional de Rosario doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 07/08/2026
🔓Be sure to read this review by Daesung Lee & co. from @uic-chemistry.bsky.social in our latest issue discussing alkyne difunctionalization via metal-nitrenoids and metal-carbenoids #orgchem Find their full article on our website👇 doi.org/10.1039/d6ob...
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