iiinova — where your digital self keeps evolving

Giuseppe Di Caprio @giudica.bsky.social · 07/10/2026

A warm welcome to Helaina Taylor, who has joined the group as a new SUSTAIN CDT PhD student. Her project will focus on developing a new device to detect mastitis in cow’s milk, in collaboration with Queen’s University Belfast. @biomedeng-strath.bsky.social

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Reposted by Giuseppe Di Caprio

BioImaging North America @bioimagingna.bsky.social · 21/09/2026

#HappyMicroscopyMonday #microscopycommunity - Can’t join us in Madison? You can still be part of I2KxBINA 2026 via Zoom Events! 🎟️ Virtual registration is FREE! 📅 Virtual registration closes September 27, 2026 Link: buff.ly/qoZqTbm

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Giuseppe Di Caprio @giudica.bsky.social · 18/09/2026

I’m often pleasantly surprised by how passionate, curious and committed our students are. They are a big part of what makes this place so special. Proud to be here, and excited about the good things still to come. @unistrathclyde.bsky.social www.strath.ac.uk/whystrathcly...

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Reposted by Giuseppe Di Caprio

Zach Marin @zacsimile.bsky.social · 17/09/2026

Happy to share our publication on MicroClaw, an AI agent that turns natural language requests into operations on any microscope controlled by Micro-Manager: www.biorxiv.org/content/10.6.... The software is single-click installable (download and click install.bat) at github.com/Micro-Claw/m....

biorxiv.org

Microscope control with a natural language agent

Microscopy underpins modern biology, but acquiring high-quality data from complex experiments at scale remains challenging. Smart microscopy can standardize and automate data collection, but each expe...

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Giuseppe Di Caprio @giudica.bsky.social · 17/09/2026

"This decline in atmospheric dust has exerted a positive effective radiative forcing of +0.02 ± 0.05 watts per square meter over 2003–2023, implying that declining atmospheric dust might have modestly contributed to the rapid warming of the past two decades."

science.org

A global decline in atmospheric dust during the 21st century

Mineral dust affects Earth’s energy budget, clouds, and biochemistry, yet the evolution of the global dust cycle in recent decades remains shrouded in uncertainty. Here we reconstruct the global dust ...

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Giuseppe Di Caprio @giudica.bsky.social · 10/09/2026

5/5 Huge congratulations to Philip Gramer, who led this work! 🎉 The bigger lesson: when comparing architectures in biomedical imaging, pretraining, evaluation and knowledge transfer may matter more than the CNN-vs-transformer headline. And this is just the first paper from our lab. 🚀

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Giuseppe Di Caprio @giudica.bsky.social · 10/09/2026

4/5 We also found a surprisingly effective way to get more from smaller models: knowledge distillation. Compact models trained to learn from multiple larger “teacher” models actually outperformed every individually trained backbone we tested, including much larger models.

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Giuseppe Di Caprio @giudica.bsky.social · 10/09/2026

3/5 So what mattered more? Pretraining. Using a pretrained model instead of training from scratch improved performance by around 3–4 points — a much bigger effect than switching between CNN and transformer. For individual cell crops, context may simply matter less.

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Giuseppe Di Caprio @giudica.bsky.social · 10/09/2026

2/5 We ran a carefully controlled benchmark on single-cell crops from LIVECell, comparing CNNs and ViTs under matched training and evaluation conditions. Once both models were pretrained, the gap between the best CNN and best transformer was less than half a point.

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Giuseppe Di Caprio @giudica.bsky.social · 10/09/2026

1/5 🎉 Our lab’s first paper is now on arXiv! arxiv.org/abs/2609.09863 We asked: does it actually matter whether you use a CNN or a Vision Transformer (ViT) to classify individual cells from microscopy images? Our answer: much less than we expected. 🧵

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Giuseppe Di Caprio @giudica.bsky.social · 03/09/2026

New review by Francesco Pasqualini on high-throughput/high-content imaging for live-cell phenotyping in tissue engineering and organoids. Importantly, they highlight the need to keep record of the whole workflow from fabrication and imaging to analysis, to improve reproducibility and interpretation.

pubs.aip.org

Engineering toolkits for high-throughput and high-content phenotyping

High-throughput/high-content (HT/HC) imaging in standard cell-line cultures has demonstrated the power of image-based phenotyping for quantitative, scalable bio

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Giuseppe Di Caprio @giudica.bsky.social · 21/08/2026

Pleased to share a review I contributed to, now published in the International Journal of Pharmaceutics: “AI-enabled lyophilization of advanced biologics: process intelligence, quality assessment, and formulation opportunities.” Thanks to Yanan for inviting me to contribute! doi.org/10.1016/j.ij...

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Reposted by Giuseppe Di Caprio

University of Glasgow @glasgow.ac.uk · 14/08/2026

Tower appreciation post ❤️ A view that never gets old! #UofG575

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Giuseppe Di Caprio @giudica.bsky.social · 13/08/2026

Really pleased to have been invited to give a talk at the UK–Japan Engineering Biology Workshop in Oxford. A great event with interesting talks and discussions. Thank you to the organisers for bringing together such a great group of people. Also a great opportunity to catch up with Mootaz Salman!

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Reposted by Giuseppe Di Caprio

University of Strathclyde @unistrathclyde.bsky.social · 18/06/2026

The University of Strathclyde has climbed 21 places to joint 230th in the QS World University Rankings 2027 – its highest-ever position in the table - putting it among the top 15% of ranked institutions worldwide and in the top 30 in the UK. www.strath.ac.uk/whystrathcly...

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Giuseppe Di Caprio @giudica.bsky.social · 15/06/2026

Two of our students are on exchanges across Europe. 🇮🇹 Grant is at ISASI-CNR in Naples, working with Giuseppe Coppola through a @royalsociety.org–CNR exchange . 🇧🇪 Swabra is at KU Leuven, exploring cardiac tissue repair and paracrine therapies. Wishing them a experience plenty of exciting science 🤓

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Reposted by Giuseppe Di Caprio

Talley Lambert @talley.codes · 16/02/2026

Rewrote my Python bioformats wrapper (from aicsimageio/bioio) as a standalone package: - fully bootstrapped Java setup (just pip install) - lazy, repeatably-indexable Array object - fully spec-compliant OME-Zarr group obj. - xarray/dask exports github.com/imaging-form... v0.0.rc1 on PyPI

github.com

GitHub - imaging-formats/bffile: Modern Bio-Formats wrapper with clean lazy Python API

Modern Bio-Formats wrapper with clean lazy Python API - imaging-formats/bffile

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Giuseppe Di Caprio @giudica.bsky.social · 06/02/2026

I just passed the Life in the UK test! Now I can forget everything 😊 (Jane Seymour who?)

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Giuseppe Di Caprio @giudica.bsky.social · 05/12/2025

Make sure to follow our department’s brand-new Bluesky account! Exciting updates coming soon. @biomedeng-strath.bsky.social

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Giuseppe Di Caprio @giudica.bsky.social · 26/11/2025

When we physicists need a manual just to look like socially functional humans at conferences 😂 apparently there’s an article for that #Networking101 #LifeofSheldon doi.org/10.1088/2058... via @ioppublishing.bsky.social

doi.org

The joy of networking - IOPscience

The joy of networking, Powrie, Honor

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Giuseppe Di Caprio @giudica.bsky.social · 19/11/2025

Had a great time at the SIPTA Forum in Huairou Science City, Beijing, together with colleagues from Imperial College, Tsinghua University, Peking University, and the Chinese Academy of Sciences. I was also fortunate to visit collaborators on the Tsinghua campus and at the Institute of Automation.

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Reposted by Giuseppe Di Caprio

Steve Quinn @steve-quinn-lab.bsky.social · 17/11/2025

🚨Only 2 more weeks to apply for our fully-funded PhD position @york.ac.uk! Want to pioneer a blood test for dementia, detect single molecules & spend time in industry with @ei-science.bsky.social?! Apply by 4th Dec: tinyurl.com/yt36p9tx It doesn't get any more EXCITING! 🔬🩸🧪

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Giuseppe Di Caprio @giudica.bsky.social · 17/11/2025

I’m pleased to share that I’ve been awarded support from the Royal Society–CNR International Exchanges scheme for a project with colleagues in Italy. We’ll combine advanced optical imaging and AI to better understand how cancer cells store fats using label-free 3D microscopy.

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Reposted by Giuseppe Di Caprio

Journal of Cell Biology @jcb.org · 31/10/2025

What do ER exit sites really look like? Using large-scale volume FIB-SEM and a custom 3D-Unet pipeline (ASEM), Nahir et al @kirchhausenlab.bsky.social reveal that ERES are vesicular, abundant & diverse, resolving long-standing morphological discrepancies rupress.org/jcb/article/... #ER_literature

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Giuseppe Di Caprio @giudica.bsky.social · 29/10/2025

I’m not sure about coffee, but I dump used tea leaves into my office plants, and they seem to like it.

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Giuseppe Di Caprio @giudica.bsky.social · 17/10/2025

A beautiful piece of work from @ruixuan3.bsky.social and @supgokul.bsky.social presenting a light-based slicing method using a photosensitive hydrogel to image large biological samples layer by layer, preserving fine structure for full 3D reconstructions.

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Giuseppe Di Caprio @giudica.bsky.social · 13/10/2025

We’re excited to welcome Grant McClure, John Selkirk, Ben Polwart, and Robert Barry, who are undertaking their 5th-year Industrial Partnership Project on the OpenFlexure Microscope, an open-source, 3D-printed laboratory microscope designed to make high-quality microscopy accessible worldwide.

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Giuseppe Di Caprio @giudica.bsky.social · 30/09/2025

Say Hi to Nicola👋🏻🔬, our shiny new Nikon microscope. Already the most popular member of the lab... Sorry everyone else 😅

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Reposted by Giuseppe Di Caprio

Nature Methods @natmethods.nature.com · 17/09/2025

A new Perspective discusses the challenges of sharing annotated image datasets and offers advice for improving bioimage annotation and reuse, particularly for AI applications. www.nature.com/articles/s41...

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Reposted by Giuseppe Di Caprio

University of Strathclyde @unistrathclyde.bsky.social · 19/09/2025

Strathclyde named Scottish University of the Year and Runner-Up UK University of the Year by The Times and Sunday Times www.strath.ac.uk/whystrathcly...

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Reposted by Giuseppe Di Caprio

Lucien Hinderling @lhinderling.bsky.social · 21/08/2025

🔬🧠 Our paper on smart microscopy & the issue of interoperability! www.biorxiv.org/content/10.1... LONG THREAD WARNING: Smart microscopy uses real-time image analysis to automatically guide the acquisition or perturbation of the sample (closed feedback-control loop). Many applications exist:

Figure legend: Categories and capabilities of smart microscopy systems integrating real-time image analysis and feedback control. Top: Smart microscopy workflows can be classified based on the driving logic behind decision-making: Event-driven (reacting to rare biological events), Outcome-driven (using feedback-control to steer biological systems toward a desired state), Quality-driven (optimizing signal quality or imaging metrics), and Information-driven (guided by models that predict which measurements/perturbations will yield the most informative data). Middle: Central feedback loop between the microscope and an image analysis system, which continuously
exchanges images and commands to guide acquisition dynamically. Bottom: Key control actions enabled by smart microscopy: adjusting imaging modality (e.g. switching from brightfield to fluorescence, adjusting sampling rate), repositioning the field of view (e.g. tracking, drift correction), optimizing acquisition settings (e.g. adaptive optics),
and performing photomanipulation (e.g. FRAP, ablation, optogenetics).

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