Increasing multidrug resistance in nosocomial, opportunistic bacterial pathogens motivates a need to exploit metabolic pathways of therapeutic value. Here, we describe a one-pot reconstitution of the ...

Alkyl CH•••S hydrogen bonding interactions enable selective transport of the antioxidant ergothioneine into bacterial cells.

Alkyl CH•••S hydrogen bonding interactions enable selective transport of the antioxidant ergothioneine into bacterial cells.

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The Department of Chemistry in the College of Arts + Sciences, consists of a well-rounded research community with cutting-edge expertise in a wide variety of modern disciplines including materials che...

The NAS Award in Molecular Biology is supported by Pfizer Inc. and recognizes a recent notable discovery by a young scientist (no older than 50) who is a citizen of the United States. The award is pre...

The bacterial ATP-binding cassette (ABC) transporter EgtU is responsible for uptake of the cellular antioxidant ergothioneine in Streptococcus pneumon…

Author summary Zn and Mn are essential micronutrients for many bacteria, including Streptococcus pneumoniae. While Zn performs vital structural or catalytic roles in certain proteins, in excess, Zn ca...

Staphylococcus aureus is one of the most common pathogens isolated from the lungs of people with cystic fibrosis (CF), but little is known about its ability to colonize this niche. We performed a Tn-s...

Experts explore the influence of trace metals on the pathogenesis of infectious diseases.Many parts of the world in which common infectious diseases are ende...