We report a water-soluble conjugated oligoelectrolyte (COE) composed of carbazole-benzophenone, COE-CbzBP, that exhibits photogenerated spin-correlated radical pair (SCRP) behavior sensitive to static...

Tissue homeostasis is dependent on precise coordination between endocrine organs in response to changes in organism physiology. Secreted circulating factors from adipocytes (called adipokines) regulat...

Here, we report the synthesis and characterization of two porous two-dimensional conjugated polyelectrolytes (2D CPEs) exhibiting persistent room-temperature open-shell character (radical/polaron) alongside dual ionic and electronic conductivity in aqueous environments. The 2D CPEs incorporate the self-doping, hydrophilic subunit potassium 4,4’-(4H-cyclopenta[2,1-b:3,4-b’]dithiophene-4,4-diyl)bis(butane-1-sulfonate) (CPDTSO3K2) with archetypal porous linkers: triphenylamine (2D CPE-TPA) and triphenyltriazine (2D CPE-TRZ). Gas physisorption measurements revealed BET (Langmuir) surface areas of 9.7 (10.4) m2·g–1 (N2) and 113 (341) m2·g–1 (CO2) for 2D CPE-TPA, and 23.7 (40.3) m2·g–1 (N2) and 142 (334) m2·g–1 (CO2) for 2D CPE-TRZ, comparable to archetypal porous polymers. Electron paramagnetic resonance (EPR) and UV–vis-NIR spectroscopy confirmed an open-shell configuration with Voigtian-shaped EPR signals. Solid-state EPR revealed a higher polaron concentration than in solution, specifically after acid-fumed exposure, revealing that intermolecular interactions enhance radical availability, stability, and interchain delocalization. Cyclic voltammetry indicated pseudocapacitive behavior with low turn-on potentials of 0.22 V (2D CPE-TPA) and 0.60 V (2D CPE-TRZ) vs Ag/AgCl. Electrochemical impedance spectroscopy estimated electrical conductivities of 1.1 mS·cm–1 (2D CPE-TPA) and 0.9 mS·cm–1 (2D CPE-TRZ), with Warburg analysis indicating higher ionic conductivity in 2D CPE-TPA (3.4 μS·cm–1) versus 2D CPE-TRZ (0.31 μS·cm–1), both correlating better with pore dimension rather than with overall porosity. Our findings underscore the role of self-doping moieties for persistent intermolecular radical formation and charge-ion transport, positioning 2D CPEs as promising electroactive porous and magnetic materials.

We report a water-soluble conjugated oligoelectrolyte (COE), Quantum-COE, exhibiting photogenerated spin-correlated radical pair (SCRP) behavior sensitive to the electric field of DNA, but not to that...

Bicyclo[2.1.1]hexane is an emerging scaffold in various pharmaceutical settings, but the scarcity of approaches to target different regioisomers from a common starting material prevents targeting a broader range of chemical space. Herein, we demonstrate a new design for the photocatalyst-controlled regiodivergent synthesis of this scaffold. Of particular interest is that the synthesis of two distinct substitution patterns was achieved under photochemical conditions with catalyst control. This was possible due to the activating group, N-methylimidazole, not only playing an important role in guiding divergent pathways but also enabling transformation to various functional groups. Transient absorption spectroscopy discerned between the regiodivergent mechanisms, as assignable bands consistent with electron transfer and energy transfer processes were distinctively observed, depending on the identity of the photocatalyst.

Stem cell self-renewal and proper tissue function rely on conserved metabolic regulators to balance energy production with inter-organ metabolic trafficking. The estrogen-related receptor (ERR) subfam...

Characterization of individual biological nanoparticles can be significantly improved by coupling complementary analytical methods. Here, we combine resistive-pulse sensing (RPS) with fluorescence lif...

YouTube video by Alexandru B Georgescu

In the past decade, conjugated oligoelectrolytes (COEs) and conjugated polyelectrolytes (CPEs) have emerged at the forefront of active materials in bioanalytical and electrochemical settings due to th...