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georg-meisl.bsky.social @georg-meisl.bsky.social · 21/02/2026

Why can cells keep protein aggregation under control for years and then suddenly tip into disease? Our new JCP paper introduces a simple phase-plane model for in vivo protein aggregation that captures the tug-of-war between aggregate formation and clearance in cells. pubs.aip.org/aip/jcp/arti...

pubs.aip.org

A universal phase-plane model for in vivo protein aggregation

Neurodegenerative diseases are driven by the accumulation of protein aggregates in the brain of affected individuals. The aggregation behavior in vitro is well

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