Single-cell and spatial multiomics analyses identify breakout lesions as a hotspot for tumor-immune interactions and diversification.

Key PointsRNA-seq analysis reveals a 6-gene signature that stratifies patients with MM by their predicted response to venetoclax.This study proposes a nove

The study provides a comprehensive transcriptomic atlas of the human gastrointestinal tract across the lifespan, highlighting inflammation-induced changes in epithelial stem cells that alter mucosal a...

Multiple myeloma (MM), one of the most frequent haematological malignancies, significantly increases the risk of bacterial infections due to treatment-related side effects, comorbidities and cancer-i....