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Philipp Altrock

@evolsci.bsky.social
550 followers 249 following 5 posts

dynamics of cancer by means of ecology & evolution, and modeling & simulation. views my own. paltrock.github.io

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Reposted by Philipp Altrock
Saez-Rodriguez Group @saezlab.bsky.social · 17/09/2025
🥁 Check out our new preprint on OmniPath, the prior knowledge resource for #SystemsBiology, and its brand-new OmniPath Explorer web app! 🥳 📖 Preprint: www.biorxiv.org/content/10.1... 🔍 Explorer: explore.omnipathdb.org OmniPath integrates 160+ resources for multi-omics analysis & modeling. 🧶⬇️
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Richard Sever @richardsever.bsky.social · 25/07/2025
"increasing reports of AI hallucinations making their way into academic papers, court decisions, and White House reports [that] have been caught by humans; One wonders how many haven’t been identified and are being spread across the information ecosystem" www.science.org/doi/10.1126/...
science.org
Why AI chatbots lie to us
A few weeks ago, a colleague of mine needed to collect and format some data from a website, and he asked the latest version of Anthropic’s generative AI system, Claude, for help. Claude cheerfully agr...
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Saloni @scientificdiscovery.dev · 09/06/2025
I wrote a new piece on how much progress has been made in treating childhood leukemia. The answer is: quite a lot! Before the 1970s, fewer than 10% of children diagnosed survived 5 years after diagnosis. Now most are cured and around 85% survive that long. ourworldindata.org/childhood-le...
Two charts present survival rates for childhood leukemia over time, specifically focusing on Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML). 

In the top panel, for ALL, a series of curved lines represent overall survival rates plotted against years since diagnosis. The lines show a marked increase in survival rates from the late 1960s, when only 14% of children survived more than five years post-diagnosis, to around 94% in the 2010s. Key intervals are labeled, with different colors indicating different periods of diagnosis, ranging from 1972-1975 to 2010-2015.

The bottom panel illustrates survival rates for AML, which are consistently lower overall compared to ALL. Like the top graph, it features several colored lines indicating specific periods. The highest point noted indicates a survival rate of 65%. The graph captures trends in survival as well, showing gradual improvement over time, from 1975-1977 up to 2011-2017.

Data sources for these visualizations are cited at the bottom: Mignon Loh et al. (2023) for ALL and Todd M Cooper et al. (2023) for AML, both from the Children's Oncology Group. The chart is published by Our World in Data, and licensed under Creative Commons by the author, Saloni Dattani.
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Brendan Harley @profharley.bsky.social · 07/06/2025
The astounding contribution of US academic science to new medicines www.statnews.com/2025/06/06/u...
statnews.com
We set out to quantify U.S. academic contributions to medicines. The results stunned even us
From 2020 to 2024, universities contributed patents underpinning 50% of FDA-approved drugs. 87% of those academic breakthroughs came from American institutions.
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David Basanta @cancerevo.org · 19/05/2025
A great blog post (3rd in the series!) from the BIRS meeting in Canada. This time by @evolsci.bsky.social @glorenzogz.bsky.social @rrockne.bsky.social amongst others Biophysically-Constrained GBM Predictions via Deep-Learning Integrating Structural SINDY with Mechanistic Filters
mathematical-oncology.org
BIRS Recap: Biophysically-Constrained GBM Predictions via Deep-Learning Integrating Structural SINDY with Mechanistic Filters
mathematical-oncology.org
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Adam Kucharski @adamjkucharski.bsky.social · 03/03/2025
New post on shallowness of Deep Research AI tools, and solutions that don’t really solve the problems we often face as scientists: kucharski.substack.com/p/the-shallo...
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Michael Baym @baym.lol · 17/02/2025
Please don’t stop sharing and posting your science because of the current attack on it, it is still valuable and reminds us what the fight is for
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Andrej Spiridonov @andrejpaleo.bsky.social · 13/01/2025
Stephen J Gould (1985) talked about the "tiers of time" with macroevolutionary dynamics distinct from short-time microevolution. But did you know that macroevolution itself shows qualitatively different dynamics at different time scales? www.nature.com/articles/s41... 🧪 #EvoBio #Paleobio ⚒️ #Geology
Space–time scaling of dominance in macroevolutionary modes
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theobioarne.bsky.social @theobioarne.bsky.social · 10/01/2025
🚨 Annual IMPRS Call for Doctoral Positions at MPI-EvolBio 🚨 🎓 Fully-funded 3.5-year doctoral projects available in diverse research areas! #PhD #ResearchOpportunities #IMPRS #Science evolbio.mpg.de/3801127/annu...
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Philipp Altrock @evolsci.bsky.social · 14/11/2024
We invite you to the “Cell Plasticity in Cancer Evolution” workshop at the MPI Evolutionary Biology, May 19–22, 2025! Join international experts who will share insights on cell plasticity in cancer and the latest research and therapies. Registration: workshops.evolbio.mpg.de/event/123/ov...
workshops.evolbio.mpg.de
Cell Plasticity in Cancer Evolution
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Rebekah Jones @georebekah.bsky.social · 08/01/2025
ABC, NBC & CBS dedicated about 16 minutes of airtime last night to the California wildfires without once mentioning climate change. Since the news failed do it's job, here's a short summary of the role of climate change and wildfire risk: www.noaa.gov/noaa-wildfir...
noaa.gov
Wildfire climate connection
Climate change, including increased heat, extended drought, and a thirsty atmosphere, has been a key driver in increasing the risk and extent of wildfires in the western United States during the last ...
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SMB - Society for Mathematical Biology @smbmathbiology.bsky.social · 04/01/2025
New #BulletinMathBio paper by Qianci Yang, Arne Traulsen, and @evolsci.bsky.social on Integration of Immune Cell-Target Cell Conjugate Dynamics Changes the Time Scale of Immune Control of Cancer. link.springer.com/article/10.1... 🧪
link.springer.com
Integration of Immune Cell-Target Cell Conjugate Dynamics Changes the Time Scale of Immune Control of Cancer - Bulletin of Mathematical Biology
The human immune system can recognize, attack, and eliminate cancer cells, but cancers can escape this immune surveillance. Variants of ecological predator–prey models can capture the dynamics of such...
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Shematologist, MD @shematologist.medsky.social · 08/12/2024
Staggering statistics at #ASH24 #TreatingFairly Patients with cancer who go bankrupt are nearly 80% more likely to die regardless of disease status. Our system quite literally kills people.
Slide on financial toxicity of cancer care
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Hank Green @hankgreen.bsky.social · 03/12/2024
The deep goal of bluesky is to decentralize the social internet so that every individual controls their experience of it rather than having it be controlled by 5 random billionaires. Everyone thinks they signed up for a demuskified twitter...we actually signed an exciting and bizarre experiment.
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Tiago Peixoto @tiago.skewed.de · 02/12/2024
It uses C++ under the hood for the heavy lifting, making it quite fast. This version includes new features, bug fixes, and improved documentation: graph-tool.skewed.de/static/doc/ Did you know that you can infer network from dynamics using graph-tool? graph-tool.skewed.de/static/doc/d... 2/N
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Sandy Anderson @sandyanderson.bsky.social · 22/11/2024
If you are attending @evomg-bcn.bsky.social or are at the @crg.eu or in Barcelona I’ll be giving the closing keynote at 11:30am on some of our on going @evoltherapy.bsky.social clinical trials as well as showing how we use @mathonco.bsky.social to drive translation.
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Anna Obenauf @obenaufa.bsky.social · 20/11/2024
Pls share 🌟Join the IMP as a Group Leader We are 👀 for a colleague, ready to lead a groundbreaking research program. Enjoy generous funding, outstanding facilities & a vibrant scientific community in one of the world's most livable cities @impvienna.bsky.social 👉https://tinyurl.com/impgl2025
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David Basanta @cancerevo.org · 17/11/2024
For those of you here interested in #MathOnco (and maybe #SomaticEvolution #CancerEvolution) this is an important resource, and since it is a newsletter you can keep up to date with the field whether you are here or twitter (or any other site): thisweekmathonco.substack.com
thisweekmathonco.substack.com
This week in Mathematical Oncology | Jeffrey West | Substack
"This week in Mathematical Oncology" -- the weekly email newsletter. Click to read This week in Mathematical Oncology, by Jeffrey West, a Substack publication with thousands of subscribers.
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Philipp Altrock @evolsci.bsky.social · 16/11/2024
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Manlio De Domenico @manlius.bsky.social · 15/11/2024
As a computational social scientist I could not miss to follow this beautiful creature: the BlueSky social network during its growth in the last hours! In this video I show just a snapshot for about 210k users and their 500k-ish connections #academicsky Zoom in the next post youtu.be/JcmYZtWGnjQ
youtu.be
The “great Xodus” and the growth of BlueSky
YouTube video by Manlio De Domenico
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Christoph Kaleta @kaletalab.bsky.social · 15/11/2024
1/3 🌍 We're hiring! The Medical Systems Biology Lab at Kiel University is looking for a passionate #PostDoc in #Metabolic #Microbiome #Modeling. Join us at one of Europe’s microbiome research hubs and push the boundaries of microbiome science! @kieluni @UKSH_KI_HL 🔗 jobs.uksh.de/job/Kiel-Pos...
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Benjamin Werner @benjaminwerner.bsky.social · 15/11/2024
Now that elife is losing its impact factor, many suggest that changing the system moving away from if may take a generation. Why should that be so? All hiring, promotion and grant committees are scientists. A few days ago, the entire scientific community leaving X also seemed unlikely!
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Ed Conway @edconway.bsky.social · 13/11/2024
Along the way I began to understand the flipside, the underbelly of the world I thought I knew. I saw where the seemingly simple materials we all rely on actually COME FROM. I saw how they’re transformed into things like silicon chips and batteries. And I realised something else:
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Philipp Altrock @evolsci.bsky.social · 14/11/2024
We invite you to the “Cell Plasticity in Cancer Evolution” workshop at the MPI Evolutionary Biology, May 19–22, 2025! Join international experts who will share insights on cell plasticity in cancer and the latest research and therapies. Registration: workshops.evolbio.mpg.de/event/123/ov...
workshops.evolbio.mpg.de
Cell Plasticity in Cancer Evolution
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Sergi Valverde @svalver.bsky.social · 12/11/2024
A starter pack for researchers interested in #ComplexSystems. Complex system science investigates how interactions among multiple parts lead to collective behaviour, as well as how the system interacts and forms links with its environment - please add your name! go.bsky.app/FNYZ61y
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Adam Kucharski @adamjkucharski.bsky.social · 13/11/2024
Why we can’t avoid models, even when getting insights from ‘raw data’ - my piece from earlier this year: kucharski.substack.com/p/we-cant-av...
kucharski.substack.com
We can't avoid models
Even insights from 'raw data' require assumptions
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Philipp Altrock @evolsci.bsky.social · 12/11/2024
Hell blue sky world! I see you're all here! can't wait!
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