Doug Epstein @epsteind.bsky.social · 23/04/2026www.nytimes.com/2026/04/23/s...nytimes.comNew Gene Therapy Enables Children With a Rare Form of Deafness to Hear 000
Doug Epstein @epsteind.bsky.social · 05/09/2025www.nytimes.com/2025/09/05/s...nytimes.comA. James Hudspeth, Who Unlocked Mysteries Behind Hearing, Dies at 79 020
Doug Epstein @epsteind.bsky.social · 20/05/2025Penn Genetics is excited to host Harmit Malik who will be giving the Bernard Cohen Memorial Lecture today. 0183
Doug Epstein @epsteind.bsky.social · 16/05/2025www.nytimes.com/2025/05/15/h...nytimes.comBaby Is Healed With World’s First Personalized Gene-Editing Treatment 050
Doug Epstein @epsteind.bsky.social · 09/04/2025www.cnn.com/2025/04/09/h...cnn.comNobel laureate: I owe America my success. Today, its scientific future is in danger | CNNDr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted... 010
Reposted by Doug EpsteinThe New York Times @nytimes.com · 06/04/2025Jehuda Lindenblatt wanted the writer Taffy Brodesser-Akner to tell his story of survival for years. In finally doing so, she reckons with how many people in her generation push away thoughts of the Holocaust to cope, only to find themselves dealing with them anyway.nyti.msThe Holocaust Story I Said I Wouldn’t WriteFor years, my friend’s father asked me to recount his childhood escape from the Nazis. Why did it take me this long? 625959
Reposted by Doug EpsteinThe New York Times @nytimes.com · 09/03/2025Breaking News: Mark Carney, a banker, will replace Justin Trudeau as Canada’s Liberal Party leader and the country’s prime minister. The party chose him to take on President Trump amid a generational crisis in Canada’s relationship with the U.S. www.nytimes.com/2025/03/09/w... 1762668393
Doug Epstein @epsteind.bsky.social · 07/03/2025Understanding the real costs of researchyoutu.beFacilities and Administrative (F&A) Costs ExplainerYouTube video by Association of American Universities 230
Reposted by Doug EpsteinMichael P Hart 🏳️🌈 (he/him) @michaelphart1.bsky.social · 26/02/2025Philadelphia Stand Up For Science! #standupforscience2025 Friday, March 7 · 11am - 1pm Philadelphia City Hall standupforscience2025.org 0167
Reposted by Doug EpsteinHearing Health Foundation @hearinghealthfn.bsky.social · 25/02/2025Happy International Cochlear Implant Day! Over the years we’ve shared so so many stories from families and individuals who are able to benefit from this life-changing technology (which we helped fund in the 1970s and '80s)! Cheers to these miracle ears! #cochlearimplants #keeplistening 022
Reposted by Doug EpsteinIshmail Abdus-Saboor @ishmailsaboor.bsky.social · 10/02/2025We did it. Fly Eagles Fly🦅🦅🦅 0121
Reposted by Doug EpsteinHearing Health Foundation @hearinghealthfn.bsky.social · 16/01/2025"Pioneering gene therapy offers hope for restoring hearing in patients with genetic hearing loss. With 155 genes linked to hearing loss and new discoveries every day, navigating this complex genetic landscape presents a monumental challenge.” From: hearinghealthmatters.org/hearing-news...hearinghealthmatters.orgEar Science Institute Australia Leads Biobank Initiative to Advance Genetic Therapies and Personalized Treatment for Hearing Loss | Hearing Health & Technology MattersEar Science Institute Australia will develop a WA-headquartered Australasian first biobank to advance genetic therapies for childhood and adult hearing loss. The Australasian Hearing Registry and Biob... 011
Reposted by Doug EpsteinShweta Ramdas @shwetaramdas.bsky.social · 04/01/2025Our mentor Casey Brown, apart from being an extraordinary scientist, was a brilliant teacher who loved everything genetics. In his honor, some of the world's leading experts came together to create the 'Casey Brown Lecture Series' on human genetics 1/ shorturl.at/eCm7Sshorturl.atCasey Brown Lecture Series - YouTube 14732
Reposted by Doug EpsteinCAMB Graduate Group @cambupenn.bsky.social · 02/01/2025New paper alert! @cambupenn G&E student @ngaboreden in the @blobellab on: LDB1 establishes multi-enhancer networks to regulate gene expressionbuff.lyLDB1 establishes multi-enhancer networks to regulate gene expression - PubMedHow specific enhancer-promoter pairing is established remains mostly unclear. Besides the CTCF/cohesin machinery, few nuclear factors have been studied for a direct role in physically connecting… 041
Reposted by Doug EpsteinCrump Lab @crumplab.bsky.social · 13/12/2024How can some vertebrates naturally recover from deafness? In work in PNAS, Tuo Shi finds that enhancers for sensory genes remain open but silent in sister cells of zebrafish and lizards, allowing these to make new inner ear sensory hair cells upon damage. www.pnas.org/doi/10.1073/... 35918
Reposted by Doug EpsteinMark Cuban @mcuban.bsky.social · 06/12/2024This is going to save hospitals a lot of money ! www.pennmedicine.org/news/news-re... 1803478486667
Reposted by Doug EpsteinᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 03/12/2024medical scientist training program (MSTP) 0326
Reposted by Doug EpsteinJeremy Berg @jeremymberg.bsky.social · 23/11/2024Following a suggestion from @benecal.bsky.social I will refer to these threads as "skeetorials" and will use this gif logo. Today's skeetorial is about the NIH Director's New Innovator Award with three different heroes (all in government). 1/nmedia.tenor.coma cartoon of homer simpson holding a cardALT: a cartoon of homer simpson holding a card 1013341
Doug Epstein @epsteind.bsky.social · 22/11/2024Our study with @ericjoyce.bsky.social led by Jailynn Harke is out. We show that allelic configurations at the Shh locus are predominately compact in the mouse forebrain, and that long range E-P interactions rely on transcription dependent and independent mechanisms. www.cell.com/molecular-ce...cell.comMultiple allelic configurations govern long-range Shh enhancer-promoter communication in the embryonic forebrainHarke et al. use sequential DNA-FISH to achieve single-allele resolution of the Sonic hedgehog (Shh) regulatory domain in the mouse forebrain. They show that multiple allelic configurations occur inde... 22811