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EMBO Molecular Medicine @embomolmed.org · 02/10/2026

#ProstaglandinE2 -mediated aging microenvironment fuels pathogenic #fibrosis in #CesareanSection scar defect By Y. Yin, Z. Li, X. Wang & colleagues Tongji University & Shanghai Jiao Tong University School of Medicine 🗞️ doi.org/10.1038/s44321-026-00521-6

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EMBO Molecular Medicine @embomolmed.org · 02/10/2026

Intratumoral androstene-3,17-dione defines #BreastCancer subtype & prognosis 👉 doi.org/10.1038/s44321-026-00530-5 By S. Asemota, H. Young Choi, R. Narayanan & colleagues @uthsc.bsky.social

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EMBO Molecular Medicine @embomolmed.org · 28/09/2026

Endothelial #SLC25A13 links #glutamine metabolism to #angiogenesis By A. Subramanian, P. Carmeliet & colleagues at KU Leuven, Leuven Cancer Institute (LKI) 🗞️ doi.org/10.1038/s44321-026-00524-3

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EMBO Molecular Medicine @embomolmed.org · 25/09/2026

Online this week ➡️ Pharmacological inhibition of #UBASH3B induces #MitoticArrest and selectively reduces #TumorGrowth By E. Pangou, @sumaralab.bsky.social and colleagues @igbmc.bsky.social 🗞️ doi.org/10.1038/s44321-026-00519-0

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EMBO Molecular Medicine @embomolmed.org · 25/09/2026

#SodiumTungstate (NaW), a pharmacological protein phosphatase inhibitor, is shown to enhance vascularization and survival of human #BetaCell grafts by A. García-Alamán, R. Gasa & colleagues @isciiisalud.bsky.social @ciberisciii.bsky.social 👉 doi.org/10.1038/s44321-026-00523-4

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EMBO Molecular Medicine @embomolmed.org · 25/09/2026

Microbiome-host communication via #VaccenicAcid modulates LRH-1/NR5A2 activity and ameliorates metabolic #LiverDisease 🗞️ doi.org/10.1038/s44321-026-00516-3 By A. Plazzo, T. Brunner and colleagues @uni-konstanz.de Highlighted in: www.uni-konstanz.de/en/universit...

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EMBO Molecular Medicine @embomolmed.org · 25/09/2026

The beautiful cover of our September issue highlights the article by H. Wong, H. Chen, N. Ip & colleagues: “#DeepPlaque: a scalable multimodal platform for Aβ pathology and cell analysis in #AlzheimersDisease” 👉 doi.org/10.1038/s44321-026-00488-4 Scientific illustration by the authors

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EMBO Molecular Medicine @embomolmed.org · 14/07/2026

New issue online! link.springer.com/journal/4432... The cover highlights the study by @awartiovaara.bsky.social, G Ince-Dunn, S Olander & al. “Loss of mitochondrial DNA helicase in retinal macroglia drives neovascular #retinopathy” 👉 doi.org/10.1038/s44321-026-00438-0 Scientific image by F Suomi

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EMBO Molecular Medicine @embomolmed.org · 10/07/2026

Online today 👉 Dermal papillary #fibroblasts promote persistent granulation tissue formation in #JunctionalEpidermolysisBullosa ➡️ doi.org/10.1038/s44321-026-00475-9 By M. Khan, M. Caley, E. Rognoni & collaborators at @qmul.bsky.social Read also www.qmul.ac.uk/news/latest-...

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EMBO Molecular Medicine @embomolmed.org · 07/07/2026

Comprehensive atlas of CD34⁺ fibroblast progenitors within the #TumorMicroenvironment 👉 differentiation trajectory toward #myofibroblasts & therapeutic targets to block this transition. 🗞️ doi.org/10.1038/s44321-026-00476-8 By J. Yang, W. Lin, L. Shen, L. Zhang & al at Shanghai University

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EMBO Molecular Medicine @embomolmed.org · 07/07/2026

CD4-directed #nanoblades enable selective #GenomeEditing in CD4+ cells and #HIV suppression in vitro and in vivo 👉 doi.org/10.1038/s44321-026-00481-x by J. Van Cleemput, L. Vandekerckhove & colleagues at Ghent University

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EMBO Molecular Medicine @embomolmed.org · 07/07/2026

Retargeted #adenoviruses for local #IgA and #CD47 blocker production as a novel cancer therapy By M. Chernyavska, W. Verdurmen & colleagues at Radboud University Medical Center 🗞️ doi.org/10.1038/s44321-026-00477-7

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EMBO Molecular Medicine @embomolmed.org · 07/07/2026

📣 Perspective by H. Medyouf, @valientelab.bsky.social & collaborators #RiseBRAINconsortium on the complexity of studying #BrainMetastases, particularly in relation to patient-derived resources. Great overview of several ongoing initiatives. 🗞️ doi.org/10.1038/s44321-026-00472-y

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EMBO Molecular Medicine @embomolmed.org · 02/07/2026

online today: #OTUB1 non-canonically inhibits #TAB2 ubiquitination to govern microglia-mediated #neuroinflammation 👉 doi.org/10.1038/s44321-026-00473-x by Zijun Cao, Xu Wang and colleagues at Wenzhou Medical University & Hannover Medical School

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EMBO Molecular Medicine @embomolmed.org · 30/06/2026

Single-nuclei UPR profiling by flow cytometry reveals #bortezomib resistance mechanisms in #MultipleMyeloma #SNUPR #cancer By J. Gigan, P. Pierre, R. Argüello & colleagues @ciml.bsky.social ➡️ doi.org/10.1038/s44321-026-00469-7

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EMBO Molecular Medicine @embomolmed.org · 30/06/2026

Online today! Impaired gephyrin G-domain trimerization and #PhaseSeparation in a patient with #DevelopmentalEpilepticEncephalopathy 🗞️ doi.org/10.1038/s44321-026-00474-w by E. Bruckish, G. Schwarz, F. Liebsch & colleagues at University of Cologne

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EMBO Molecular Medicine @embomolmed.org · 15/06/2026

Extracellular #cyclophilinA promotes B-cell #AcuteLymphoblasticLeukemia progression via MC2R 👉 doi.org/10.1038/s44321-026-00466-w By H. Z. Pei, Y. Guo, W. Liu, L. Sun & colleagues at Chinese Academy of Sciences

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EMBO Molecular Medicine @embomolmed.org · 15/06/2026

S100A10-ANXA2 tetramer inhibition hampers #HepaticStellateCell activation in human #MASLD #organoids By M. Türkal, P. Maecher, E. Delangre & colleagues at University of Geneva 🗞️ doi.org/10.1038/s44321-026-00464-y

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EMBO Molecular Medicine @embomolmed.org · 15/06/2026

New issue online! The cover illustrates the article by H. Woo, Y. Jang, M. Zheng, S.M. Man, R. Karki et al. ➡️ doi.org/10.1038/s44321-026-00425-5 Pharmacological targeting of the #NLRP3 LRR domain with #isothiazolinones overcomes CRID3-resistant #inflammation Scientific image by H. Woo & R. Karki

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EMBO Molecular Medicine @embomolmed.org · 08/06/2026

🫁 #NETosis associates with human #tuberculosis lung tissue destruction and disease pathogenesis ➡️ doi.org/10.1038/s44321-026-00435-3 By K. Fisher, M. Marakalala & colleagues at @ahri-news.bsky.social and Stellenbosch University

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EMBO Molecular Medicine @embomolmed.org · 08/06/2026

Functional screening of TCR-like antibodies using STAR-T cell library for #cancer #immunotherapy By Yi Li, Xin Lin & colleagues at Tsinghua University ➡️ doi.org/10.1038/s44321-026-00455-z

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EMBO Molecular Medicine @embomolmed.org · 29/05/2026

Soluble #TREM2 engages cell-surface nucleolin to drive #VascularPermeability and malignant ascites in #OvarianCancer 🗞️ doi.org/10.1038/s44321-026-00452-2 by Q. Li, X. Huang, S. Guo, B. Xie, H. He & colleagues at University of Macau & The Fifth Affiliated Hospital of Sun Yat-sen University

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EMBO Molecular Medicine @embomolmed.org · 29/05/2026

Mitochondrial activity promotes #neutrophil degranulation and endothelial dysfunction in #SystemicInfections By P. Zakrzewski, B. Amulic & colleagues @bristoluni.bsky.social 👉 doi.org/10.1038/s44321-026-00453-1

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EMBO Molecular Medicine @embomolmed.org · 29/05/2026

NeoCircle: pre- and post-operative #ctDNA dynamics predicts survival in neoadjuvant-treated early #BreastCancer By A. George, @laosaal.bsky.social & colleagues at @lund-university.bsky.social 🗞️ doi.org/10.1038/s44321-026-00447-z Press release: www.lunduniversity.lu.se/article/bloo...

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EMBO Molecular Medicine @embomolmed.org · 20/05/2026

WEE1 kinase inhibition to overcome #acquired #resistance to targeted therapies in #ColorectalCancer By K. Buzo, S. Arena & colleagues at Candiolo Cancer Institute & University of Torino 👉 doi.org/10.1038/s443...

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EMBO Molecular Medicine @embomolmed.org · 20/05/2026

#Adipocytes influence #choroidal #neovascularization via PRDM16 🗞️ doi.org/10.1038/s44321-026-00441-5 by A. Wilson, S. Crespo-Garcia, P. Sapieha & colleagues @umontreal-en.bsky.social

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EMBO Molecular Medicine @embomolmed.org · 20/05/2026

New issue online! link.springer.com/journal/4432... The beautiful cover highlights the article by O. Join-Lambert, @demangelab.bsky.social & colleagues @pasteur.fr @inserm.fr ➡️ doi.org/10.1038/s44321-026-00407-7 Scientific image by Inta Gribonika

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EMBO Molecular Medicine @embomolmed.org · 12/05/2026

#GutMicrobiota -modulated #GlutamicAcid rejuvenates the quality of #oocytes deteriorated by advanced reproductive age By Feixue Wang, Bo Xiong and colleagues at Nanjing Agricultural University & Zhejiang University 🗞️ doi.org/10.1038/s44321-026-00443-3

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EMBO Molecular Medicine @embomolmed.org · 12/05/2026

Loss of mitochondrial DNA helicase in retinal macroglia drives #neovascular #retinopathy ➡️ doi.org/10.1038/s44321-026-00438-0 by S. Olander, G. Ince-Dunn, @awartiovaara.bsky.social & colleagues @helsinki.fi

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EMBO Molecular Medicine @embomolmed.org · 12/05/2026

New Perspective by @sarah-delliere.bsky.social & @nicolaspaponangers.bsky.social ➡️ Innovation in #antifungal therapy Angers University & @pasteur.fr 🗞️ doi.org/10.1038/s44321-026-00449-x

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EMBO Molecular Medicine @embomolmed.org · 12/05/2026

CCDC174 deficiency impaired human #fertility by affecting the #AlternativeSplicing of maternal mRNAs By Weijie Wang, Lei Wang, Qing Sang & colleagues at Fudan University ➡️ 🗞️ doi.org/10.1038/s44321-026-00448-y

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EMBO Molecular Medicine @embomolmed.org · 12/05/2026

Online today! TMPRSS2-ERG confers resistance of #ProstateCancer to #antiandrogens 👉 doi.org/10.1038/s44321-026-00423-7 by A. Sekar, Y. Yarden & colleagues at Weizmann Institute of Science

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EMBO Molecular Medicine @embomolmed.org · 07/05/2026

Costimulation loss enhances IL-2-driven #Treg generation by PI3K-STAT3 inhibition in #CNS #autoimmunity ➡️ doi.org/10.1038/s44321-026-00431-7 By Kyung-Ho Nam, Je-Min Choi & colleagues at Hanyang University

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EMBO Molecular Medicine @embomolmed.org · 07/05/2026

Distinct pathophysiological mechanisms of #CEP152 variants in #microcephaly and #BrainAbnormalities By Nanako Hamada, Koh-ichi Nagata & colleagues @en.nagoya-u.ac.jp 🗞️ doi.org/10.1038/s44321-026-00427-3

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EMBO Molecular Medicine @embomolmed.org · 04/05/2026

George Sen & Longlong Luo at University of California, San Diego, propose that RNA-dependent #chromatin architecture influence gene programs in #skin cells and create lasting “structural scars” after #inflammation, influencing future responses 🗞️ doi.org/10.1038/s44321-026-00440-6

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EMBO Molecular Medicine @embomolmed.org · 04/05/2026

A multimodal pipeline combining #snRNAseq, #SpatialTranscriptomics and ex vivo tissue-slice culture maps cell states and drug responses in SMARCB1-deficient #SinonasalCarcinoma -> doi.org/10.1038/s44321-026-00437-1 By P. Jurmeister, S. Flach, F. Klauschen, A. Mock & colleagues @lmu.de

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EMBO Molecular Medicine @embomolmed.org · 01/05/2026

New Resource: Disease-stage-specific immunometabolic remodeling in #PediatricObstructiveSleepApnea: a single-cell #TranscriptomicAtlas of adenoid tissue ➡️ doi.org/10.1038/s44321-026-00419-3 By Q. Yang, H. Pan, S. Qin & colleagues at Hospital Zhejiang University School of Medicine

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EMBO Molecular Medicine @embomolmed.org · 01/05/2026

Interstitial and recruited #macrophages prevent #tuberculosis relapse by limiting immune evasion ➡️ doi.org/10.1038/s44321-026-00432-6 By V. Vinette, @saehrt.bsky.social and colleagues @weillcornell.bsky.social

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EMBO Molecular Medicine @embomolmed.org · 21/04/2026

Our April issue is online! link.springer.com/journal/4432... This month’s cover highlights the article by N. Brose, M. Tirard & colleagues, #Encephalopathy -linked #UFM1 variants impede neuronal protein translation, development, and function ➡️ doi.org/10.1038/s44321-026-00389-6

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EMBO Molecular Medicine @embomolmed.org · 14/04/2026

Impaired #vitaminD signaling reveals #neutrophils as key drivers of #ProstateCancer dissemination 🗞️ doi.org/10.1038/s44321-026-00417-5 by K. Len-Tayon, @gilleslaverny.bsky.social & colleagues @igbmc.bsky.social

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EMBO Molecular Medicine @embomolmed.org · 09/04/2026

Broadly neutralizing #nanobodies target a defined structural pivot site on the #RSV fusion protein 🦠 ➡️ doi.org/10.1038/s44321-026-00412-w By Q. Wang, B. Shu, S. Chiu and colleagues atWuhan Institute of Virology & University of Science and Technology of China

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EMBO Molecular Medicine @embomolmed.org · 09/04/2026

❗Read the new Review on anti-tubercular target validation by Valerie Mizrahi at University of Cape Town, Dirk Schnappinger @weillcornell.bsky.social & colleagues ➡️ doi.org/10.1038/s44321-026-00415-7 #tuberculosis

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EMBO Molecular Medicine @embomolmed.org · 09/04/2026

#Hyperglycemia impairs #CognitiveFunction by inducing mitochondrial damage through #lactylation of LRPPRC at K223 👉 doi.org/10.1038/s44321-026-00422-8 by J. Xu, T. Zheng & colleagues at Guilin Medical University

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EMBO Molecular Medicine @embomolmed.org · 09/04/2026

📣The anti-obesogenic metabolite, Lac-Phe, is elevated by #metformin treatment in #ProstateCancer patients By M. Bilusic, D. Lombard, P. Rai & colleagues at University of Miami Miller School of Medicine 🗞️ doi.org/10.1038/s44321-026-00408-6

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EMBO Molecular Medicine @embomolmed.org · 01/04/2026

Online today! #Tomatidine is a #senotherapeutic compound that improves cognitive function and reduces cellular senescence in aged mice By D. Costa, @dianajurk.bsky.social & colleagues @mayoclinic.org 🗞️ doi.org/10.1038/s44321-026-00400-0

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EMBO Molecular Medicine @embomolmed.org · 01/04/2026

JAK1/2 inhibitor #ruxolitinib reduces aggregates in cardiac #proteinopathy By E. Alizoti, S. R. Singh & colleagues @dzhk.de 🗞️ doi.org/10.1038/s44321-026-00411-x

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EMBO Molecular Medicine @embomolmed.org · 01/04/2026

The lipid transfer protein #STARD7 controls intestinal tumor development in a context-dependent manner 👉 doi.org/10.1038/s44321-026-00409-5 by K. Shostak, A. Chariot & colleagues at University of Liege & WEL Research Institute

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EMBO Molecular Medicine @embomolmed.org · 01/04/2026

#TenascinC orchestrates #radiotherapy -induced head and neck tumor regression #HNSCC by T. Loustau, G. Orend & colleagues @unistra.fr @inserm.fr 🗞️ doi.org/10.1038/s44321-026-00406-8

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EMBO Molecular Medicine @embomolmed.org · 01/04/2026

Bcl-xL blockade targets #neutrophils and synergizes with #chemotherapy in #LungSquamousCellCarcinoma ➡️ doi.org/10.1038/s44321-026-00401-z by A. Mayet, E. Meylan & colleagues @ulbruxelles.bsky.social & University of Lausanne

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EMBO Molecular Medicine @embomolmed.org · 25/03/2026

CDK12/CDK13 inhibition disrupts transcriptional elongation and #ReplicationFork progression in #glioblastoma By S. Lier, M. Lerdrup, D. Pandey & colleagues at University of Copenhagen & University of Oslo 🗞️ doi.org/10.1038/s44321-026-00393-w

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