Gerring et al. report opportunities for drug repurposing in amyotrophic lateral sclerosis by leveraging large-scale genomic datasets. Their analysis priori

Anorexia nervosa (AN) is an eating disorder for which the underlying aetiology remains mostly uncharacterised. Large-scale genetic studies of AN suggest a relationship between AN liability and cardiom...

Glioma is an aggressive brain tumor subtype with few known risk factors. Here, the authors utilise Mendelian Randomisation to investigate correlation of immune cell counts with subtype-specific risk a...

Circuit and cell type prioritization for complex disorders is crucial to direct future efforts. Here the authors integrate GWAS, human single-cell RNA-seq and fMRI analysis suggesting multi-modality c...