Syncytiotrophoblasts (STs) are multinucleated cells formed by the fusion of trophoblasts and play critical roles in placental development and function. Retrovirus-derived fusogenic proteins, known as ...

Abstract figure legend Transforming growth factor (TGF)-β2 and interleukin (IL)-1β induced morphological and molecular changes consistent with endothelial-to-mesenchymal transition (EndMT) in HUVECs ...

Gestational diabetes mellitus (GDM) increases the risk of pathological fetal growth, including rates of large-for-gestational age (LGA) infants, which…

The Northern EV Network aims to bring together scientists interested in extracellular vesicle research across the North of England.

Type 2 diabetes (T2D) now accounts for the majority of pre-existing diabetes affecting pregnancy in the UK. Our aim was to determine its impact on pregnancy outcomes compared to type 1 diabetes (T1D), gestational diabetes (GDM) and non-diabetes pregnancies.

In cattle, communication between endometrium and conceptus during the peri-implantation period is crucial for successful pregnancy. Understanding these interactions is vital as most early pregnancy lo...

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A platform for mRNA lipid nanoparticle delivery to the placenta to treat pre-eclampsia is shown to improve fetal and maternal health in mice and has potential clinical applications in obstetric disorders and women's health.

In most countries, especially in low-income and middle-income countries, diabetes treatment has not increased at all or has not increased sufficiently in comparison with the rise in prevalence. The bu...