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Sam "The Mug Guy" Horrell

@drhorrell.bsky.social
984 followers 1.5K following 257 posts

Scientist 🧑‍🔬, structural biologist 🧬, X-ray Crystallographer 💎, Synchrotron Mug Enthusiast ☕, D&D 🎲 and MTG player 🧙, bird dad to Nori and Kili 🦜🦜 He/Him

PostsRepliesMedia
Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 06/11/2025
I'm currently at LCLS in Stanford, anyone got a lead on where I might find a #SynchrotonMug to add to my collection? I know they exist. I've seen pictures!
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 04/09/2025
All three are adorable thanks 🙂
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 26/08/2025
Finally, a detector suitable for the new SynchroGnome beamlines. A giant leap forward in tiny science. #ROD10atECM #ECM
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 26/08/2025
I don't have a Crystallography themed hat, so I guess I need to get one made out of something edible.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 26/08/2025
Why would we bother guessing anything else?
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 25/08/2025
It's actually in P 21 21 21, but we can still meet up for that beer if you spot me at the conference.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 25/08/2025
Who are you wagering? Becuase I know the answer already 😉
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 25/08/2025
Disappointingly it was P21 21 21.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 25/08/2025
Made it to Poznan for the European Crystallography Meeting. Looking forward to presenting at the Science Slam on Thursday with the help of my cat Rosalind. #Crystallography #ECM35 #StructuralBiology #ScienceCommunication #SciComm #ScienceSlam
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 20/08/2025
Top notch pun work. Truly immaculate.
media.tenor.com
a man with a beard is wearing a crown and saying you bow to no one .
ALT: a man with a beard is wearing a crown and saying you bow to no one .
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 20/08/2025
I don't want to alarm anyone, but I think my electron density might be haunted. 💎👻💀
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 11/08/2025
Said goodbye to the @dectris.bsky.social Pilatus 6M the other day with one last #DetectorSelfie featuring beamline scientist Sofia. Collected some data to 0.87 A to give it a proper send off. Not sure how many images it has taken on I24 but it is very deserving of a rest.
2 people, a woman wearing glasses and a man with a beard, taking a picture in the reflective surface of a photon counting detector.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 19/06/2025
Protein structure or #Minecraft Creeper?
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 13/06/2025
Taking bets on if this is crystalline or not. We'll find out next week on @diamondlightsource.bsky.social's VMXm next week with the help of @adamcrawshaw.bsky.social.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 05/06/2025
The electron microscope can't believe you just said that.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 29/05/2025
After 2 weeks of antibiotics twice a day Nori (left) now has a clean bill of health. Kili (right) is clearly pleased about this too.
A light yellow and grey cockateil and a dark grey peid cockateil put their heads together. One has their beak wide open. Both have very orange cheeks.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 22/05/2025
I was minding my own business watching a music video when suddenly I see @thewarningarmy.bsky.social have managed to crystallise themselves. So I thought I'd see if they diffract, and they do! #Crystallography #TheWarning #Crystal #Diffraction
A regular repeating pattern of Ale, Pau, and Danny from the  rock band The Warning. Effectively forming a 2D crystal of the band members. The reulsting diffraction pattern of the crystallised members of the warning. A Grey background with white spots in a regular repeating pattern.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 16/05/2025
Naturally
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 15/05/2025
If this #crystal space group isn't P3 or P6 I'll eat my #crystallography hat. It also reminds me of a tiny allen key.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 08/05/2025
I don't see a major and a minor groove, and there are fewer that 4 bases per turn.
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Reposted by Sam "The Mug Guy" Horrell
RCSB Protein Data Bank @rcsbpdb.bsky.social · 04/05/2025
Changes in PDB IDs are coming that will require use of PDBx/mmCIF file format... will you be ready? #MayThe4th Resources are available to help: www.wwpdb.org/docume...
Him: Structures in PDB format
Her: Do you mean mmCIF and not deprecated format, right?
Him: 
Her: RIGHT?
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 04/05/2025
Happy #StarWars day from Nori and Kili. May the fourth be with you.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 02/05/2025
Pretty successful draft at the local game store. Won the event and got a chonky dragon. #MTG #MagicTheGathering
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 01/05/2025
Blue copper crystals on a silicon chip.
A black silicon chip with regular etched square holes covered in blue/purple crystals.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 01/05/2025
New paper out today on a cyclic peptide which interacts with CD59, a protein that inhibits the complement mediated membrane attack complex. Some cool structural work went into this, modelling the cyclic peptide was an interesting challenge. onlinelibrary.wiley.com/doi/abs/10.1...
onlinelibrary.wiley.com
Macrocyclic Peptide Probes for Immunomodulatory Protein CD59: Potent Modulators of Bacterial Toxin Activity and Antibody‐Dependent Cytotoxicity
CD59 is an immunomodulatory cell surface receptor associated with human disease. Despite its importance in complement regulation and bacterial pathogenesis, CD59 remains a challenging therapeutic tar....
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 28/04/2025
I made Ojer Axonil spell slinger group slug and it has quickly become one of my favourites. First mono deck was Gisa Glorious Resurrector.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 18/04/2025
¡Olé! ¡Olé! ¡Olé! WARNING! Had a great time watching #TheWarning at Brixton last night.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 16/04/2025
It's a protein called Isocitrate dehydrogenase 1 (IDH1). No salt crystals here.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 16/04/2025
Did someone say protein crystals? Someone probably said protein crystals.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 15/04/2025
Also a good shout #PandemicFlashBacks
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 15/04/2025
What are the Rolling Stones doing in my electron density?
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 15/04/2025
Do you think it's surprised to see me?
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 15/04/2025
Classic Isoleucine behaviour
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 15/04/2025
This is Kili. Their interests include screaming and eating broccoli.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 15/04/2025
Post Bird?
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Reposted by Sam "The Mug Guy" Horrell
Martin Nutbeem @martinnutbeem.bsky.social · 15/04/2025
Post dog.
A large shaggy white dog sits next to a dog bed. He's giving his dogface.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 14/04/2025
Every crystallographer needs one.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 14/04/2025
A purrfectly normal envelope to have slid under my office door as a Crystallographer.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 13/04/2025
Hmm, looks orthorhombic primitive to me.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 07/04/2025
Thanks, glad you enjoyed it 😊
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 03/04/2025
Had a lot of fun at the London final of #FameLab yesterday. Unfortunately as the runner up I won't be at the national final, but I did win the audience vote! Thanks for the kind words and advice from the judges @robinince.bsky.social, @funsizesuze.bsky.social, and @catherineloveday.bsky.social.
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Reposted by Sam "The Mug Guy" Horrell
The Spike Feeders @spikefeeders.com · 28/03/2025
IF YOU WANT TO WIN THE PRECONS WE PLAYED, REPOST THIS POST! We're giving them away inside a @gamegenic.com CARDS LAIR PRO 1000+ CONVERTIBLE! We'll pick a winner on Monday, March 31 at 12pm CT. Must follow us and @gamegenic.com to qualify.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 27/03/2025
It is digital, so as long as I don't print it out we're all good.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 26/03/2025
From now on, if you're not wearing the appropriate PPE while using a Sharpie in the lab I'm going to have to have words with you. For safety.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 19/03/2025
You got this
media.tenor.com
a man is pointing at a sign that says `` believe '' while another man looks on .
ALT: a man is pointing at a sign that says `` believe '' while another man looks on .
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 15/03/2025
I'll be presenting at the London #FameLab final in a few weeks! If there are any Londoners looking for an evening of accessible science talks you can get (free) tickets here. www.eventbrite.co.uk/e/london-fam...
eventbrite.co.uk
London FameLab Final
Experience the excitement of the London FameLab Final! Enjoy engaging science talks as contestants compete for a place in the UK Final.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 10/03/2025
They can't be allowed to live
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Reposted by Sam "The Mug Guy" Horrell
Charles Bayly-Jones @charlesbj.bsky.social · 09/03/2025
Sigh... the "protein folding problem" ≠ "structure predicition".
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 08/03/2025
The magic of pressure washing.
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Sam "The Mug Guy" Horrell @drhorrell.bsky.social · 07/03/2025
Sounds pretty.
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