Parents used to be advised to keep allergenic foods like eggs away from babies, especially if allergies ran in the family. But based on recent and evolving evidence, the advice is now almost the oppos...

Eosinophilic esophagitis (EoE) is a common, chronic, immune-mediated disease of the esophagus, affecting approximately 1 in 700 individuals in the United States. Despite rising prevalence, clinical ma...

The atopic march refers to the natural history of allergic disease manifestations as they develop in childhood.1 Classically, the march begins with atopic dermatitis (AD), followed sequentially by foo...

We detected a modest association between dupilumab and cutaneous autoimmune disease diagnosis in atopic children. These findings help address knowledge gaps about clinical outcomes in atopic children treated with this biologic.

Omeprazole diminished the effects of IL-13 in both the epithelial air-liquid interface model and eosinophil-epithelial co-cultures, alleviating barrier dysfunction, chemokine expression, and the upregulation of eosinophil adhesion markers.

In a cohort of 1200 children on OIT at a tertiary pediatric hospital with robust OIT and EoE programs, the rate of newly diagnosed EoE during OIT was found to be 0.7%, which is lower than prior studies. This study demonstrated regular screening before and during OIT is associated with a reduced rate …

We found that oesophageal epithelial cells upregulate MHCII expression during active EoE in humans and a mouse model. MHCII expression by EECs was governed by IFNγ-inducible transcriptional elements....

Immense progress in gene editing, drug discovery and conservation are just some of the reasons to be cheerful about 2025.

The Nuremberg Code and Its Lasting Relevance to Allergy and Immunology

Households that struggle to pay for items like egg substitute and soy milk can find them at the health system's Buerger Center. And a delivery program is in the works.

Podcast Episode · Primary Care Perspectives · 12/09/2025 · 30m

Allergic diseases have reached epidemic proportions globally, calling attention to the need for better treatment and preventive approaches. Herein, we developed allergen-encoding messenger RNA (mRNA)-lipid nanoparticle (LNP) strategies for both therapy and prevention of allergic responses. Immunizat …

Surprisingly, all cell types examined exhibited differences between patients and controls. Monocytes and NK cells, the cell types least likely to be directly impacted by thymic effects, had unique patterns of gene expression, although both were highly altered in patients. This suggests a widespread …

There was a 43% decline in peanut allergies among U.S. children under 3 after the release of new early introduction guidelines.

It’s nuts how effective these new guidelines are.

New data suggest that early peanut exposure may cut the risk of allergic reactions. Newsweek asked experts what parents should do.

A landmark trial in 2015 found that feeding peanuts to babies could cut their chances of developing an allergy by more than 80 percent.