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Reposted by Abhimanyu

JCI insight @insight.jci.org · 01/10/2025

This case series highlights risk factors for infection by a non-tuberculous mycobacterium. Ananya Gupta @drabhi.bsky.social et al. link GATA2 mutation in the context of immune dysfunction to enhanced susceptibility to M. heamophilum infection in humans: buff.ly/pPIhSlx

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Abhimanyu @drabhi.bsky.social · 10/08/2025

Happy to share this interesting study which is now in press. We found specific Non-tuberculous mycobacterial susceptibility linked to GATA2 mutation in immunocompromised individuals @uchicagobsd.bsky.social @jci-insight.bsky.social insight.jci.org/articles/vie...

insight.jci.org

JCI Insight - GATA2 mutation is associated with immune dysfunction and increased Mycobacterium haemophilum susceptibility in immunocompromised individuals

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Reposted by Abhimanyu

Bryan Bryson @thebrysonlab.bsky.social · 21/07/2025

Newest paper from the lab out today (doi.org/10.1084/jem....)! Here, we describe PathMHC, a novel MS-based approach to identify rare pathogen-derived peptides on MHC-I and MHC-II. We apply this to a range of pathogens Mtb, SARS-CoV-2, and Listeria.

doi.org

Targeting infection-specific peptides in immunopeptidomics studies for vaccine target discovery

MS-based immunopeptidomics can facilitate vaccine antigen discovery, but self-MHC peptides greatly outnumber pathogen-derived MHC peptides, presenting a ch

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Abhimanyu @drabhi.bsky.social · 21/04/2025

In the midst of everything take a break , protect your sanity and refuel to keep at it . #easter #timeoff #vitaminsea

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Abhimanyu @drabhi.bsky.social · 21/01/2025

Happy to be part of this cool paper ! BCG trial for prevention of COVID-19 in healthcare workers, interrupted with speedy arrival of the COVID vaccines. The vaccinated cohort 12-months later show improved COVID-19 immunity, key player DNA methylation! #BCG #DNAmethylation @globaltb.bsky.social

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Abhimanyu @drabhi.bsky.social · 02/01/2025

Happy 2025! Ready to get back to the science after a reset trip to beautiful #sanfrancisco #yosemite

At the view point in Yosemite El Captain

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Abhimanyu @drabhi.bsky.social · 15/11/2024

A good day spent in listening to talks from four neighboring labs which are incidentally on the same floor . From #proteinengineering , #phageengineering , hightroughput #microfluidics and traditional conditional knockout #micemodels . #uchicago . Science is in good hands !

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Reposted by Abhimanyu

Olivier Neyrolles @oneyrolles.bsky.social · 11/11/2024

I made a Starter Pack for the Myco & TB community. Hope to find more good friends here on Bluesky to keep in touch about mycobacterial infections. Please join and repost! go.bsky.app/3nwpcVV

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