iiinova — where your digital self keeps evolving

Dmitry Mylarshchikov @dmitrymyl.bsky.social · 21/08/2026

Huge thanks to my co-first author Zsuzsanna Takacs, my advisors @danielgerlich.bsky.social and @golobor.bsky.social, and our whole team for making this happen!

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Dmitry Mylarshchikov @dmitrymyl.bsky.social · 21/08/2026

Thrilled to share a huge piece of my PhD! 🎉 We show how replicated chromosomes maintain sister chromatid cohesion while still actively folding loops within nested TAD hierarchy. Read the full paper here: link.springer.com/article/10.1... 🧬👇

link.springer.com

Nested TAD hierarchy defines cohesion zones on replicated chromosomes - The EMBO Journal

During each cell cycle, cells must not only duplicate the DNA sequence but also preserve the three-dimensional genome architecture required for gene regulation and DNA repair. After replication, this ...

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Dmitry Mylarshchikov @dmitrymyl.bsky.social · 12/02/2025

Happy to share our recent preprint from @gerlichlab.bsky.social @imbavienna.bsky.social on the role of cohesins in homology search! 🥳🧬

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