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Djaoud Lab

@djaoudlab.bsky.social
90 followers 85 following 11 posts

Research group of Dr. Zakia Djaoud at University of Ottawa and CHEO Research Institute. Enthusiasts for γδ T cells.

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Djaoud Lab @djaoudlab.bsky.social · 23/06/2026
📢Postdoc Opportunity! Join us in beautiful Ottawa to study γδ T cells in health&disease. Ideal for PhD immunologists in innate lymphocytes, who will lead projects in spectral flow cytometry, multi-omics and in vivo models. Send CV+cover letter to Z. Djaoud. @forum-gd.bsky.social #gdTcells #NKcells
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JCI insight @insight.jci.org · 17/06/2026
@zdjaoud.bsky.social & team @djaoudlab.bsky.social report KIR surface proteins distinguish 2 human γδ T-cell subsets: one memory-like with strong effector potential & another less-differentiated subset with a naïve-like phenotype: doi.org/10.1172/jci....
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Djaoud Lab @djaoudlab.bsky.social · 10/06/2026
The edited version of our latest manuscript is now online! We show that KIR⁺γδ T cells are enriched in CMV⁺ individuals and that KIR expression marks γδ T-cell differentiation, cytotoxicity and immune adaptation @insight.jci.org #gdTcells @forum-gd.bsky.social #CMV insight.jci.org/articles/vie...
insight.jci.org
JCI Insight - Killer-cell immunoglobulin-like receptors define a potent effector program in human γδ T cells
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Djaoud Lab @djaoudlab.bsky.social · 29/04/2026
Thanks, @forum-gd.bsky.social, for sharing our preprint! The final edited version will be available soon!
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Djaoud Lab @djaoudlab.bsky.social · 26/11/2025
At our latest lab journal club, with Angélque Cayer, we discussed PMC10711208: a study showing γδ T cells preferentially kill HPV-transformed and cancer cervical organoids, linked to DNA-damage pathways & BTN3A1/BTN2A1. #γδTcells #CancerImmunology #HPV #Organoids www.frontiersin.org/journals/imm...
frontiersin.org
Frontiers | γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids
Cervical cancer is a leading cause of death among women globally, primarily driven by high-risk papillomaviruses. However, the effectiveness of chemotherapy ...
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Djaoud Lab @djaoudlab.bsky.social · 16/11/2025
More than an association. Looks like it’s through EBNA2! By @shady-myounis.bsky.social et al., @stanforddeptmed.bsky.social. www.science.org/doi/10.1126/...
science.org
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells to promote pathogenic antinuclear T and B cell responses in lupus.
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Djaoud Lab @djaoudlab.bsky.social · 24/10/2025
At yesterday’s lab journal club, with @yeganeh-almasi.bsky.social, we discussed PMC10848161: A case study showing γδ T cells driving lasting anti-tumor immunity during PD-1 blockade in Merkel cell carcinoma. @natcomms.nature.com #Immunotherapy #γδTcells www.nature.com/articles/s41...
nature.com
Tumor reactive γδ T cells contribute to a complete response to PD-1 blockade in a Merkel cell carcinoma patient - Nature Communications
Immune checkpoint blockade cancer therapy has been designed to enable tumor killing by conventional αβ T cells. Here authors show that in a Merkel cell carcinoma patient showing complete response to a...
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Djaoud Lab @djaoudlab.bsky.social · 10/10/2025
At today’s lab journal club, we discussed PMC12306285: a trispecific killer engager targeting B7-H3 that boosts NK cell activity against head & neck cancer, even under hypoxia. #Immunotherapy #NKcells #CancerResearch #ImmunoSky jitc.bmj.com/content/13/7...
jitc.bmj.com
Novel trispecific killer engager targeting B7-H3 enhances natural killer cell antitumor activity against head and neck cancer
Background Patients with head and neck squamous cell carcinoma (HNSCC), particularly the human papillomavirus negative (HPV −) subset, have a dismal prognosis. Furthermore, patients with Fanconi anemi...
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Izabella A. Pena, PhD 🇧🇷🇨🇦 @izabellapena.bsky.social · 02/10/2025
My lab (1st photo), together with the Djaoud lab (2nd photo) took a little break from the lab to enjoy the stunning fall colors and crisp air at Gatineau Park. It was a refreshing gathering, full of connection and shared appreciation for each other, celebrating the accomplishments this past semester
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Djaoud Lab @djaoudlab.bsky.social · 24/05/2025
We had an amazing γδ T Cell Conference with @yeganeh-almasi.bsky.social, @marileel.bsky.social & the incredible #gdTcells community, @forum-gd.bsky.social. Yeganeh & Marilee presented their work on KIR-enriched polyclonal γδ T cells in cancer immunotherapy. See you all in Wrocław in two years!
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γδ T cell Forum @forum-gd.bsky.social · 08/01/2025
The program for the 11th International γδ T Cell Conference is now live! Visit www.gammadeltatoronto.ca and register before the early bird deadline (Jan 13). #gdTcells #gd2025 #BestConferenceEver
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Djaoud Lab @djaoudlab.bsky.social · 08/01/2025
CMV elicits an expansion of CD16+CD8+ innate-like T cells, including αβ and γδ T cells, in utero. @jclinical-invest.bsky.social www.jci.org/articles/vie...
jci.org
JCI - In utero human cytomegalovirus infection expands NK-like FcγRIII+CD8+ T cells that mediate Fc antibody functions
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