Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 17/09/2026Molecules like these have the potential to fight #antibioticresistance by working as adjuvents - acting to restore the power of existing antibiotics. #DrugDiscovery 000
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 17/09/2026Happy New Paper Day! We're excited to share this @natchembio.nature.com on #SmallMoleculeInhibitors of NorA, an efflux pump that is an important mediator of #antibioticresistance in #MRSA. It pumps antibiotics out , lowering their concentration in the cell. doi.org/10.1038/s415...doi.orgSmall-molecule inhibitors block NorA efflux by conformational trapping - Nature Chemical BiologyMultidrug efflux pumps expel antibiotics, contributing to antibiotic resistance. Now, high-throughput screening and structural characterization reveal an inhibitor of Staphylococcus aureus efflux pump... 112
Reposted by Drug Discovery Unit, University of DundeeGuðjón Ólafsson @godjohn.bsky.social · 15/07/2026A fully funded PhD position is now open in my lab at the University of Iceland. We are looking for an ambitious researcher to join us in Reykjavik, Iceland to work on targeted protein degradation. Interested? You are welcome to contact me or check out: 🔗https://euraxess.ec.europa.eu/jobs/452601 086
Reposted by Drug Discovery Unit, University of DundeeManu De Rycker @mdr-ddu.bsky.social · 01/06/2026Our #Trypanosoma cruzi single-cell atlas paper is now available online! Great work by Ross Laidlaw and Marta Garcia Sanchez, and excellent collaboration with Thomas Otto! rdcu.be/flOWR @ddu-dundee.bsky.social, @dundeeuni.bsky.social #single-cell, #Chagas, #atlas, #trypanosome, #scRNA-seq 🧪🔬rdcu.beTrypanosoma cruzi cell atlas as a single-cell resource for understanding parasite population heterogeneity and differentiationNature Communications - Here, Laidlaw, Garcia Sanchez and colleagues present a single-cell atlas for Trypanosoma cruzi, an important protozoan pathogen, providing insights into cell heterogeneity,... 086
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 26/05/2026Rabbitt highlights the #FemTech revolution & the surge of women investors who are finally putting their money where our health is, aggressively closing that research gap. #WomeninSTEM #WomensHealth #WomensHealthMonth #BookReview #DDUat20 000
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 26/05/2026The narrative doesn’t shy away from the frustrating reality that women’s health has been chronically underfunded & overlooked, leaving us decades behind in research & effective treatments. However, there’s a hopeful spark here... #MedicalSexism #HealthEquity 110
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 26/05/2026By fully understanding what is happening to our bodies in the present, we can be better prepared for what lies ahead; this shifts the narrative from being reactive once a problem arises to being proactive with conditions like heart disease before they progress. #WomensHealth #HealthAwareness 100
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 26/05/2026The book makes a compelling case for why your gynaecological history, such as #preeclampsia or #gestationaldiabetes, aren't just isolated events, but early warning signs for #cardiovascular health later in life. #WomensHealthMonth 100
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 26/05/2026This book serves as a roadmap for navigating a system that has long ignored female-specific biology. Rabbitt dismantles the archaic notion that women should stoically endure debilitating symptoms like chronic period pain or severe hot flushes as "normal" life stages. #MedicalSexism #HealthEquity 100
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 26/05/2026Hi sky-pals! We here at DDU towers hope you are keeping cool in these hot May days! Let's continue our #BookReviews as part of #WomensHealthMonth, give you something to read over your lunch break! Today we're reading Meghan Rabbitt’s The New Rules of Women’s Health #DDUat20 141
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 22/05/2026By bridging the gap between data & lived experience, Perez proves that the medical field’s failure to collect sex-disaggregated data isn't just an oversight it is a life-threatening flaw. The book reveals a system that doesn't just ignore women, but fundamentally fails to understand them. 010
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 22/05/2026Perez also discusses the #YentlSyndrome, where women’s pain is frequently dismissed as psychosomatic, leading to a staggering average of eight years to diagnose conditions like #endometriosis! #WomensHealthMonth #PillarsofWomensHealth 100
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 22/05/2026Women are 50% more likely to be misdiagnosed during heart attacks because their symptoms don't match the standard male chest pain. Drugs are often dosed based on male physiology, leading to higher #adversereaction rates in women. #HealthEquity #DrugDevelopment #MedicalSexism 152
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 22/05/2026It turns out, treating women like "men with extra hormones" is about as effective as using a map of Dundee to navigate New York! This bias has devastating consequences in both diagnosis of conditions (see our Pillars of women's health!) & development of treatments #InvisibleWomen #HealthEquity 100
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 22/05/2026In it, she reviews the gender data gap in healthcare, where the 70 kg Caucasian male serves as the universal default. Perez argues that by excluding women from clinical trials to avoid hormonal complexity, medicine treats the female body as an atypical version of man. #MedicalSexism 110
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 22/05/2026Happy Friday y'all! Hope you all had a good week. We've got some more #BookReviews for you for #WomensHealthMonth. This morning we are talking about "Invisible Women - Exposing data bias in a world designed for men" by @ccriadoperez.bsky.social #DDUat20 #HealthEquity #WomenInSTEM #InvisibleWomen 132
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 21/05/2026Ultimately, the birth of gynaecology depended entirely on the intellectual and physical endurance of Black women. Their uncredited labour remains the invisible bedrock of modern reproductive medicine. #BlackInSTEM #FeministHistory #HealthEquity 010
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 21/05/2026However, their contribution extended far beyond being passive subjects. Lacking professional staff, these women were forced to act as skilled surgical assistants. This #MedicalBondage created a system where were they were both subjects & staff. #MedicalEthics 100
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 21/05/2026J. Marion Sims, hailed as the father of #gynaecology, used enslaved women for experimental surgeries, providing essential clinical data to cure conditions which had previously rendered many enslaved women "unproductive" in both labour and childbearing. #BlackWomen #MedicalEthics 100
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 21/05/2026Following the 1808 transatlantic slave trade ban, slaveholders relied on reproduction to maintain the enslaved population. Reproductive health became a matter of intense economic concern, incentivising doctors to specialise in repairing reproductive injuries. #History #Bioethics 110
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 21/05/2026Deirdre Cooper Owens’ book Medical Bondage redefines the history of American gynaecology. By centring enslaved Black women, she reveals them not just as victims, but as foundational contributors to the medical field. #BlackHistory #MedicalHistory #WomensHealthMonth 100
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 21/05/2026Morning skypals! Tea-break time seems like a good time for a book review - how about it? We will start with Medical Bondage, by Deirdre Cooper Owens, an American historian & reproductive rights activist #womenshealthmonth #DDUat20 #BookReview 131
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 18/05/2026NHS urged to update website after renaming polycystic ovary syndrome (as polyendocrine metabolic syndrome (PMOS) - missing from the headline) #womenshealthmonth #DDUat20 #PMOS www.theguardian.com/society/2026...theguardian.comNHS urged to update website after renaming polycystic ovary syndromeCharity says absence of new name polyendocrine metabolic syndrome (PMOS) could cause confusion 011
Reposted by Drug Discovery Unit, University of DundeebioRxiv Microbiology @biorxiv-microbiol.bsky.social · 18/05/2026Mycobacteriophage TM4 requires XylR for successful infection in Mycobacterium smegmatis mc2155 www.biorxiv.org/content/10.64898/20… 031
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 18/05/2026Good morning skypals! We hope you all have a relaxing weekend and are looking forward to a great week! This week we have some excellent book reviews to share for #WomensHealthMonth What have you got coming up? 121
Reposted by Drug Discovery Unit, University of DundeeChemistry World @chemistryworld.com · 14/05/2026The difference between isoleucine and valine is not that great, which made isoleucine the ideal target for substitution, but simply replacing isoleucine with valine didn’t work as well as hoped. Read on: www.chemistryworld.com/news/strippe...chemistryworld.comStripped down bacterium functions with one less amino acid than the rest of life on EarthDeep learning models used to understand how isoleucine could be replaced in proteins without disrupting their structures 043
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 13/05/2026....is the #GTA in the room with you... 000
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 13/05/2026Got a science shaped hole in your Monday evening? Why not pop along to #PintofScience! Rosie Street-Jeakings & Christopher Bailey are both talking about #malaria research. Get your tickets at the link! pintofscience.co.uk/event/drugs-...pintofscience.co.ukDrugs and Bugs: The Fight for Global HealthWhy does disease only target certain people? How do we make new treatments for that disease? Does your postcode alter the treatment you get? These are all … 012
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 12/05/2026We reposted this article in much excitement, but it's really worth a read! "Polyendocrine metabolic ovarian syndrome, the new name for polycystic ovary syndrome: a multistep global consensus process" Names are important! #womenshealthmonth #DDUat20 000
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 12/05/2026This is really good 000
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 12/05/2026#womenshealthmonth #threepillarsofwomenshealth 101
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 12/05/2026Congratulations to Prof Doreen Cantrell on her election to US-based National Academy of Sciences @nasonline.org #WomenInScience www.biodundee.co.uk/science-city...biodundee.co.ukDundee scientist recognised with top international honour | Welcome to Bio-DundeeA pioneering University of Dundee academic has received international recognition after being elected to one of the world’s foremost scientific institutions. 022
Reposted by Drug Discovery Unit, University of DundeeWellcome Sanger Institute @sangerinstitute.bsky.social · 12/05/2026Women’s health has long been underfunded and understudied. This Women’s Health Month, see how our researchers are using genomics to uncover new insights to improve outcomes for women worldwide. Read more: sangerinstitute.blog/2026/05/12/way… 032
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 12/05/2026In March 2025, we hosted an #Endometriosis Networking Workshop with experts from across the field. We’re excited to share the resulting white paper! A huge thanks to all who contributed to these vital discussions. Read here: www.linkedin.com/posts/possib... #DrugDiscovery #WomensHealth #DDUat20linkedin.comPossible Strategies for Drug Discovery for Endometriosis | Drug Discovery Unit, University of DundeeIn March 2025, we convened an Endometriosis Networking Workshop, bringing together academics, clinicians, industry leaders, and venture capitalists to collaboratively explore how we can advance drug d... 002
Reposted by Drug Discovery Unit, University of DundeeBiochemical Society @biochemsoc.bsky.social · 11/05/2026Final call for anyone interested in an opportunity to join our editorial boards and journals! Applications lose at midday today, 11 May 2026. Help shape the future of Society publishing, we are looking forward to hearing from you. Apply here for our current Spring cycle: ow.ly/1VvK50YXcH7 001
Reposted by Drug Discovery Unit, University of DundeePrecisionLife @precisionlife.bsky.social · 08/05/2026New data presented at #EEC2026 identified and validated novel reproducible genetic risk factors associated with endometriosis across UK & US patient cohorts. 🎥 Watch the presentation: precisionlife.com/womens-healt... 📜 Read the preprint: www.medrxiv.org/content/10.1... #WomensHealthMonthprecisionlife.comEndometriosis Genetic Risk Factors Identified and ValidatedWatch Krystyna Taylor present PrecisionLife’s validation of genetic risk factors for endometriosis using combinatorial analysis. 011
Reposted by Drug Discovery Unit, University of DundeeAlzheimer's Association @alzassociation.bsky.social · 02/05/2026Almost two-thirds of Americans with Alzheimer's are women. By adopting these healthy habits, we can all protect our brain health: alz.org/healthyhabits. #WomensHealthMonth 052
Reposted by Drug Discovery Unit, University of DundeeAAMC @aamc.org · 06/05/2026When Elizabeth Blackwell became the first woman in the U.S. to earn an MD in 1849, her male classmates didn’t expect her to change medicine forever. This #WomensHealthMonth, explore what Blackwell’s legacy can teach us, 175+ years later. aamc.orgA Lady Alone: The story of Elizabeth Blackwell, MD, the first female physician in the United StatesAdmitted to medical school on a whim, Blackwell became a dominant force in the fight for women’s health care and for the education of women physicians. 032
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 10/05/2026Relevant to #WomensHealthMonth! 043
Reposted by Drug Discovery Unit, University of DundeeNature @nature.com · 10/05/2026Experienced researchers are less likely to produce ‘disruptive’ science than are those just starting their careers, finds an analysis of scientific papers published by 12.5 million researchers over 60 years go.nature.com/3Pb1lqggo.nature.comEarly-career researchers do more ‘disruptive’ science than veteransNature - Analysis of papers from millions of scientists shows that older researchers tend to stick with ideas from their past. 14613
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 04/05/2026So, let's talk about it! First off, we want to talk about the three pillars of women's health... #WomensHealthMonth #DDUat20 #GlobalHealth 011
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 04/05/2026We would like to say in advance, for the purposes of these posts "women's health" encompasses people who were assigned female at birth. This is a scientific classification not a sociological one and nothing in here negates the lived experiences of trans people. #WomensHealthMonth 120
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 04/05/2026Good morning sky-friends! We hope you are well on this lovely #mayday bank holiday! May is #WomensHealthMonth and we have lots of interesting things we want to talk about! 041
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 25/04/2026"...a new antimalarial drug that has recently completed Phase 2 clinical trials in Africa, sponsored by @merckgroup.bsky.social. Cabamiquine is a very promising medicine.” Dr Beatriz Baragana #NowWeCanNowWeMust #WorldMalariaDay #DrugDiscovery #GlobalHealth #InfectiousDiseases #EndMalaria #DDUAT20 110
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 25/04/2026"Since 2010, the DDU malaria team, working with academic and industry partners, has been dedicated to discovering new medicines to treat and prevent malaria. One major success has been the discovery of Cabamiquine (DDD498)..." #NowWeCanNowWeMust #WorldMalariaDay #Research #EndMalaria #DDUAT20 232
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 25/04/2026..."before reactivating and causing repeated illness. Our goal is to develop a medicine that can fully clear this hidden infection and prevent malaria from returning." Dr Beatriz Baragana Ending malaria means tackling every stage of the disease. #NowWeCanNowWeMust #WorldMalariaDay #DDUAT20 110
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 25/04/2026“Over the past two years, we have also been working with @novartis.bsky.social to develop a new drug aimed at stopping malaria relapses. These relapses are caused by a form of malaria that can hide in the liver for months or even years after infection..." #NowWeCanNowWeMust #WorldMalariaDay 221
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 25/04/2026To prevent this unnecessary loss of life, existing tools must reach every community at risk, & continued investment in the development of innovative medicines & prevention strategies is essential. Ending malaria starts with protecting those most at risk. #NowWeCanNowWeMust #WorldMalariaDay #DDUAT20 020
Drug Discovery Unit, University of Dundee @ddu-dundee.bsky.social · 25/04/2026Children under five and pregnant women are the most at risk from malaria, accounting for the majority of the approximately 600,000 deaths each year worldwide. #NowWeCanNowWeMust #WorldMalariaDay #EndMalaria #GlobalHealth #HealthEquity #DrugDiscovery #InfectiousDiseases #PublicHealth #DDUAT20 133