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David Mas-Ponte

@david.masponte.com
404 followers 1.3K following 85 posts

Postdoc at @humantechnopole.bsky.social working with Andrea Sottoriva to study the evolutionary rules of cancer. Previously at UW Genome Sciences and @irbbarcelona.org 🔗 david.masponte.com

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David Mas-Ponte @david.masponte.com · 02/02/2026
finally february 😅
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David Mas-Ponte @david.masponte.com · 21/11/2025
Catalan human towers ("Castells") in the 25th anniversary ad from Wikipedia 🔝 ca.wikipedia.org/wiki/Castells
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Kevin Wright @kevinmawright.bsky.social · 17/11/2025
Sure. Just one question: How?
media.tenor.com
a man in a purple suit and top hat is making a funny face
ALT: a man in a purple suit and top hat is making a funny face
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David Mas-Ponte @david.masponte.com · 11/11/2025
The google-scholar pdf reader just added syntax highlighting 😱 I really needed this haha
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David Mas-Ponte @david.masponte.com · 05/11/2025
the infographic is really bad... but there are some gems in the actual pdf plan, with different and more detailed routes. Wildest to me Scandinavia <-> Mediterranean route. Stocholm, Berlin 8h and Berlin to Naples in 11-ish hours. transport.ec.europa.eu/document/dow...
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Fabian Zimmermann @fabianzimmermann.bsky.social · 31/10/2025
Been a fan since v1 so I’ll give v3 a try, too. I liked how easy it was to switch from adobe products. And so far I’ve never missed any feature. Any estimates how much academia funnels into adobe per year?
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David Mas-Ponte @david.masponte.com · 31/10/2025
This is big news for academics, a fully* featured, modern vector editor software for free (hopefully) forever. We should be sad when research money is unnecessarily directed to the adobe whirlpool of subscriptions.
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David Mas-Ponte @david.masponte.com · 24/10/2025
Wow! great feature in the newest @typst.app update 🎉🎉
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David Mas-Ponte @david.masponte.com · 20/10/2025
also bocconi university
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David Mas-Ponte @david.masponte.com · 25/09/2025
when the test is significant but you forgot to check its effect size
discounted product, from 1,50 to 1,49
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David Mas-Ponte @david.masponte.com · 24/09/2025
Science aside, the typesetting of this preprint is beautiful. Apple-worthy
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David Mas-Ponte @david.masponte.com · 27/08/2025
media.tenor.com
a woman in a blue dress is talking to a man in a blue shirt .
ALT: a woman in a blue dress is talking to a man in a blue shirt .
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David Mas-Ponte @david.masponte.com · 05/08/2025
TIL you can create a multiqc compatible json/yml file and will just work out the box. docs.seqera.io/multiqc/cust...
docs.seqera.io
Custom content | Seqera Docs
Report on your data, even without a MultiQC module
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David Mas-Ponte @david.masponte.com · 25/07/2025
Big fan of this hand drawn wholesome graphical abstract in today's @cp-cell.bsky.social 🐜
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David Mas-Ponte @david.masponte.com · 10/07/2025
TIL that the Gendarmerie (military police) in France uses GendBuntu, a slight modification of ubuntu. And everything because they didn't want to move from Windows XP to vista 😅 en.wikipedia.org/wiki/GendBuntu
en.wikipedia.org
GendBuntu - Wikipedia
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Hadley Wickham @hadley.nz · 03/06/2025
At Posit, we love @typst.app: ⚡ Make PDFs in milliseconds, not minutes ✨ The power of LaTeX with today's technologies ✍️ Modern typography (including emojis!) 🧠 Clear mental model So I'm thrilled to announce that we're now supporting its development: posit.co/blog/posit-a... #rstats
posit.co
Posit
We’re happy to announce that we’re supporting Typst by funding one of their full-time engineers.
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Zeqian Li @zeqianli.bsky.social · 28/05/2025
I started tgv to learn Rust and building it has been unbelievably fun! If you wanna pick up a super fast and fun programming language, tgv is open for contribution! There aren't many bioinformatics tools built entirely by the community. If tgv can become one, I'll be so psyched
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David Mas-Ponte @david.masponte.com · 19/04/2025
*advertisement payed by a VC fund 😅
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David Mas-Ponte @david.masponte.com · 11/04/2025
Never thought i would say this but R becoming more pythonic is a good thing 🙃 "R 4.5.0 introduces a new way to load objects from a package: use()"
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Darren Dahly @statsepi.bsky.social · 06/04/2025
American scientists aren't special. It's the institutions, and willingness to spend on research, that set them apart. Similarly invest here, and you will naturally attract the best talent from *everywhere*. www.politico.eu/article/euro...
politico.eu
Europe to burned American scientists: We’ll take you in
The EU’s body for scientific research, as well as local, regional and national governments, are mobilizing to poach top U.S. scholars.
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Twonks @twonks.bsky.social · 27/03/2025
Still life
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David Mas-Ponte @david.masponte.com · 24/03/2025
23andMe to be sold off now, agree with @philippbayer.bsky.social it's likely there ll be a opt out mechanism for people that don't want their data distributed to pharma companies, but just glad I managed to delete my data on the site under GDPR, thanks EU 👌
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David Mas-Ponte @david.masponte.com · 16/03/2025
this is really cool! 😎 obsidian is now free for all, simplicity over subscriptions
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kepano @stephango.com · 15/03/2025
opening files in Obsidian, not sped up
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David Mas-Ponte @david.masponte.com · 25/02/2025
🏔️🏔️🏔️ #flashes
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David Mas-Ponte @david.masponte.com · 24/02/2025
Excited about the HTML experimental feature in @typst.app 0.13! 👏 typst.app/blog/2025/ty...
typst.app
Typst 0.13 is out now – Typst Blog
With Typst 0.13, we wanted to improve the day-to-day experience of using Typst. We fixed some of the most long-standing bugs and made Typst even more flexible to...
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Reposted by David Mas-Ponte
Keith Robison @omicsomics.bsky.social · 20/02/2025
Roche Ripple Predictions My take on how Roche SBX will roil the sequencing landscape omicsomics.blogspot.com/2025/02/roch... 🧬🖥️
omicsomics.blogspot.com
Roche Ripple Predictions
In the prior piece , I covered the technical details unveiled by Roche for their SBX technology, but generally tried to avoid predicting its...
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David Mas-Ponte @david.masponte.com · 21/02/2025
What a world we live in that the highest cost of a DNA sequencer is the computer+GPU instead of the "sequencing" itself, big benefits for SBX if AI bubble pops eventually "the biggest expense [...] is assuredly the compute onboard" by @omicsomics.bsky.social omicsomics.blogspot.com/2025/02/roch...
omicsomics.blogspot.com
Roche Xpounds on New Sequencing Technology
Bar bets can be a powerful force in human society.  One of the best known books on the planet, The Guinness Book of World Records, originate...
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David Mas-Ponte @david.masponte.com · 12/02/2025
@dieworkwear.bsky.social
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David Mas-Ponte @david.masponte.com · 10/02/2025
by @mnot.net on UK's demands to Apple 1. Comply 🔪 (seriously harm their core values and reputation) 2. Apple-xit 💸 (leave UK and lose 1.5Bn) 3. Decentralize 👥, would be cool to self-host your own iCloud data and would probably set the example to other companies www.mnot.net/blog/2025/02...
mnot.net
Apple’s Best Option: Decentralize iCloud
What can Apple do in the face of a UK order to weaken encryption worldwide? Decentralize iCloud, to start.
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David Mas-Ponte @david.masponte.com · 09/02/2025
Placing European cities in a map is more complicated than it seems because regional definitions of metropolitan areas are not consistent. For instance, metro area in Barcelona is weird, includes heavily unpopulated areas in mountainous terrain where people cannot live, also airport and harbor
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David Mas-Ponte @david.masponte.com · 09/02/2025
Great thread from @tommytang.bsky.social on why we need workflow managers in biology! Hard disagree on "[snakemake] feels natural for anyone familiar with Python scripting" though 😜
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David Mas-Ponte @david.masponte.com · 04/02/2025
👀
HN screenshot
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zeu @zeu.dev · 23/01/2025
i’m so tired but i’ve got obligations 😩
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David Mas-Ponte @david.masponte.com · 23/01/2025
Europe PMC is a PubMed-like site, underrated IMO (the API is top notch), but as far as I know, it relies on PubMed for sourcing their data (some sort of mirror?) Wondering if there is a switch to make it independent somehow? Probably just depends on publishers sending their data there instead?
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David Mas-Ponte @david.masponte.com · 15/01/2025
pro tip, every youtube channel has an associated RSS feed, add them to a rss reader and you can get a complete algorithm (and advertisement) free experience.
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David Mas-Ponte @david.masponte.com · 09/01/2025
Longevity startups if humans were worms
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Caleb Lareau @caleblareau.bsky.social · 08/01/2025
Out today in @naturegenet.bsky.social -- PERFF-seq! With @tsionabay.bsky.social , @ronanchaligne.bsky.social, Bob Stickels, Meril Takizawa, + Ansu Satpathy, we describe this new assay to study rare populations with programmable nucleic acid cytometry. 1/n www.nature.com/articles/s41...
nature.com
Transcript-specific enrichment enables profiling of rare cell states via single-cell RNA sequencing - Nature Genetics
Programmable Enrichment via RNA FlowFISH by sequencing (PERFF-seq) isolates rare cells based on RNA marker transcripts for single-cell RNA sequencing profiling of complex tissues, with applicability t...
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Carlos Caldas 🇵🇹🇮🇱🇪🇺🇬🇧 @carloscaldas1960.bsky.social · 05/01/2025
Register with @helloeacr.bsky.social Lisbon will be amazing! @eacrnews
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David Mas-Ponte @david.masponte.com · 05/01/2025
it's nice that now new biotech are already publishing a processing bioinformatics pipeline for their new tool/service, integrating the molecular biology and standardizing outputs
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David Mas-Ponte @david.masponte.com · 05/01/2025
Single Amino Acid Variant (SAAV) was not in my bingo card for this year (late 2024 actually). A new test for the adaptability of the VCF standard 😅 From Quantum-SI who are pushing their NGPS (Next Generation Protein Sequencing). www.biorxiv.org/content/10.1...
biorxiv.org
Detecting Amino Acid Variants Using Next-Generation Protein Sequencing (NGPS)
Next-Generation Protein Sequencing™ (NGPS) is a single-molecule approach for characterizing protein variants, offering detailed insight into proteoforms and amino acid substitutions not easily discern...
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Stephen Turner @stephenturner.us · 02/01/2025
One of my favorite talks at the @nextflow.io summit was @kenibrewer.bsky.social's talk on how to NOT contribute to nf-core (using nf-core in your organization). He wrote a nice post on the @nf-co.re blog on building an nf-core style modules library for your organization seqera.io/blog/buildin...
seqera.io
Building an nf-core style modules library for your organization | Seqera
If you would like to bring nf-core’s approach to enabling code within your own organization, you can!
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Institut d'Estudis Catalans @iec.cat · 02/01/2025
#IEC 🔴 | Mor el científic Joan Guinovart, fundador de l’Institut de Recerca Biomèdica de Barcelona i membre de la Secció de Ciències Biològiques de l’IEC. Des de l’Institut d’Estudis Catalans volem donar el nostre més sentit condol a familiars i amics. ➡️ www.iec.cat/noticia/?id_...
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David Mas-Ponte @david.masponte.com · 12/12/2024
also wild how consistent the PGS for ADHD is....
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David Mas-Ponte @david.masponte.com · 11/12/2024
Reminds me of what Jeff Bezos said in a podcast "The advantage of compromise as a resolution mechanism is that it's low energy, but it doesn't lead to truth" You cannot really expect to "break the system" and maintain your position within such system at the same time.
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David Mas-Ponte @david.masponte.com · 04/12/2024
Reading @natureportfolio.bsky.social these days....
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David Mas-Ponte @david.masponte.com · 03/12/2024
while my experience with the Seqera AI hasn't been great (possible I asked impossible tasks) the vs-code integration is a MAJOR improvement. Really thankful for the upgrade! eg. hovering over process/workflow names you see its output channels directly, no switching to other files anymore 🚀
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David Mas-Ponte @david.masponte.com · 03/12/2024
Can't wait for Bryan Johnson to add these into the "Blueprint" 😂
buff.ly
What’s the secret to living to 100? Centenarian stem cells could offer clues
A bank of cells from people more than 100 years old gives scientists a new resource for studying longevity.
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David Mas-Ponte @david.masponte.com · 01/12/2024
really cool story on the central "dogma" by @matthewcobb.bsky.social got me thinking why there isn't any case for the direct translation of DNA 🤔 open.substack.com/pub/cell/p/c...
open.substack.com
Francis Crick Was Misunderstood
The Central Dogma is not a 'dogma,' and it has never been broken.
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