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Zeqian Li

@zeqianli.bsky.social
78 followers 35 following 29 posts

Principal Bioinformatics Scientist @BillionToOne. Formerly Seppe Kuehn Lab (UChicago)

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Zeqian Li @zeqianli.bsky.social · 04/10/2026
Silicon valley feels like this now
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Zeqian Li @zeqianli.bsky.social · 09/09/2026
Taking a mini sabbatical next month to work on open-source bioinformatics. Any folks in the bay area wanna connect?
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Zeqian Li @zeqianli.bsky.social · 07/09/2026
Best thing I've watched in a long time youtu.be/hpj6r6CjJf8?...
youtu.be
Casey Muratori – The Root of The Root of All Evil – BSC 2026
YouTube video by Better Software Conference
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Zeqian Li @zeqianli.bsky.social · 21/06/2026
Now you can! tgv 0.3.0: - Browse multiple alignment/VCF/BED files - Experimental support for base modifications (MM/ML) - Bug fixes - Lots of internal work too to support upcoming features github.com/zeqianli/tgv
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Zeqian Li @zeqianli.bsky.social · 20/06/2026
Can your terminal do this
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Reposted by Zeqian Li
Ragnar {Groot Koerkamp} @curiouscoding.nl · 04/06/2026
Now that Sassy had been published and presented, it's time for it to break out of my bubble :) curiouscoding.nl/posts/sassy/ www.reddit.com/r/rust/comme...
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Zeqian Li @zeqianli.bsky.social · 19/04/2026
New tgv release! tgv now remembers your session by quitting with :wq. This release switches from rust-htslib to the native noodles library and reimplemented the S3 support through openDAL. The low-level API will enable finer optimization in the future. github.com/zeqianli/tgv
github.com
GitHub - zeqianli/tgv: Explore genomes in the terminal. Light, blazing fast 🚀, vim-motion.
Explore genomes in the terminal. Light, blazing fast 🚀, vim-motion. - zeqianli/tgv
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Zeqian Li @zeqianli.bsky.social · 20/03/2026
Yesss
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Reposted by Zeqian Li
Zeqian Li @zeqianli.bsky.social · 08/09/2025
tgv 0.1.0 release: github.com/zeqianli/tgv - Rich CIGAR and base visualization - Allele frequency visualization - VCF and BED file support - Mouse dragging and hovering - Filter alignment Now 90% of what I need from IGV can be done in the terminal. Some interesting behind-the-scenes:
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Zeqian Li @zeqianli.bsky.social · 08/09/2025
tgv 0.1.0 release: github.com/zeqianli/tgv - Rich CIGAR and base visualization - Allele frequency visualization - VCF and BED file support - Mouse dragging and hovering - Filter alignment Now 90% of what I need from IGV can be done in the terminal. Some interesting behind-the-scenes:
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Zeqian Li @zeqianli.bsky.social · 05/09/2025
Come on Claude, I give you one more chance. This is just a simple refactoring. I wrote instructions in comments. I'll write a good prompt. I'll use your PRO model with MAX reasoning. You got it. No mistake. > Deletes all the code
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Zeqian Li @zeqianli.bsky.social · 27/08/2025
Types are cool but how do I explain this
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Zeqian Li @zeqianli.bsky.social · 16/08/2025
tgv is becoming so good. Next release gonna be epic. On a side note, I stopped using AI all together a month ago (except occasionally turning on tabbing for boilerplate). I'm so much happier. Coding is much more flowy and I'm learning a ton. Vim motion boosts productivity way more than any AI.
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Zeqian Li @zeqianli.bsky.social · 24/07/2025
Anyone uses marimo notebooks regularly? What do you use it for?
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Zeqian Li @zeqianli.bsky.social · 20/07/2025
New tgv release: local cache! tgv download hg38 Download UCSC reference genomes to a local sqlite db for much faster browsing. Awesome Rust tools (twobit, bigtools) made this simple. github.com/zeqianli/tgv
github.com
GitHub - zeqianli/tgv: Explore 5,000+ genomes in the terminal. Light, blazing fast 🚀, vim-motion.
Explore 5,000+ genomes in the terminal. Light, blazing fast 🚀, vim-motion. - zeqianli/tgv
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Zeqian Li @zeqianli.bsky.social · 28/05/2025
I started tgv to learn Rust and building it has been unbelievably fun! If you wanna pick up a super fast and fun programming language, tgv is open for contribution! There aren't many bioinformatics tools built entirely by the community. If tgv can become one, I'll be so psyched
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