Scientists have discovered a rare genetic condition which causes people to age at a much faster rate, offering fresh insights into the ageing process.

With advancing age, clock-like DNA-methylation changes occur across the genome. Whether these changes are passenger events or drive pathology remains to be determined. Here we report a novel epigeneti...

This study investigates the consequences of hypermethylation in a progeria syndrome caused by gain-of-function DNMT3A mutations, finding effects on adult stem cell function.