iiinova — where your digital self keeps evolving

Dan Johnson @danmjohnson.bsky.social · 20/02/2026

Abstract submission deadline approaching for the 50th EWGCCE! Join us 6–8 July 2026 in Leuven 🇧🇪 to celebrate 50 years of cardiac cellular electrophysiology. Submit your abstract today (or by 2nd March! 😀) Looking forward to seeing you there! #EWGCCE esc365.escardio.org/event/2035

esc365.escardio.org

50th EWGCCE Meeting 2026 on ESC 365

Seminar on Cellular Electrophysiology by the WG on Cardiac Cellular Electrophysiology to improve your practice and prepare for your exams.

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Reposted by Dan Johnson

JMCC Plus @jmccplus.bsky.social · 09/02/2026

Stuck between a ROCK2 and a hard place? New research just out shows selective ROCK2 inhibition reduces microvascular obstruction after myocardial I/R but doesn’t limit infarct size. Highlights distinct roles for ROCK isoforms in #cardioprotection. 🫀 www.sciencedirect.com/science/arti... #CardioSky

sciencedirect.com

Selective ROCK2 inhibition reduces microvascular obstruction but does not reduce myocardial infarction after ischaemia and reperfusion

Myocardial ischaemia/reperfusion (I/R) injury causes infarction, microvascular obstruction (MVO), and haemorrhage. MVO, often driven by vasospasm, lac…

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Reposted by Dan Johnson

JMCC Plus @jmccplus.bsky.social · 05/02/2026

🫀New research demonstrates that high-throughput, label-free optical oxygen measurements can assess adrenergic effects in iPSC-derived #cardiomyocytes Paired with all-optical #electrophysiology, this enables scalable, human-based preclinical testing #CardioSky www.sciencedirect.com/science/arti...

sciencedirect.com

Response of human iPSC-cardiomyocytes to adrenergic drugs assessed by high-throughput pericellular oxygen measurements and computational modeling

Rate- and contractility-modulating drugs, such as adrenergic agonists and antagonists, are widely used in the treatment of cardiovascular conditions. …

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Dan Johnson @danmjohnson.bsky.social · 20/01/2026

The #deadline for our special edition of @jphysiol.bsky.social looking at Crosstalk of cells in the #heart has been extended until March 6th! Feel free to get in touch or check out the call on the website! physoc.onlinelibrary.wiley.com/hub/journal/... @physoc.bsky.social

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Dan Johnson @danmjohnson.bsky.social · 09/12/2025

Are you working on #cellular #cross-talk in the #heart? Looking for an outlet for your work? Look no further! Molly O Reillyy, Chris 'O Shea and I are editing an edition of @jphysiol.bsky.social Deadline 6th Jan! #CardioSky physoc.onlinelibrary.wiley.com/hub/journal/...

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Dan Johnson @danmjohnson.bsky.social · 05/12/2025

Final Call! 🫀 Boost your cardiac research career! Scientific Exchange Grants from the WG Cellular Cardiac Electrophysiology offer €2,500 for a 1-month stay in a European lab. Great chance to learn new skills + collaborate internationally. Apply by 8 Dec 2025 👉 escardio.org/Research/Res...

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Reposted by Dan Johnson

JMCC Plus @jmccplus.bsky.social · 01/12/2025

Rab10 to the rescue! 🦸‍♂️🫀! New study from Xu et al. in the December issue shows how this tiny protein helps keep harmful heart growth in check. Read more at: www.sciencedirect.com/science/arti... #CardioProtection #Hypertrophy #CardioSky

sciencedirect.com

Rab10 plays a protective role in the development of pathological cardiac hypertrophy

Prolonged cardiac hypertrophy is a main risk factor for heart failure (HF). During cardiac hypertrophy remodelling, there is an increase in protein sy…

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Dan Johnson @danmjohnson.bsky.social · 26/11/2025

🚀 Calling all early-career cellular cardiac #electrophysiology researchers! The @escardio.bsky.social is offering Scientific Exchange Grants for short-term research visits across Europe 🌍. 📅 Deadline: 8 Dec 2025 — don’t miss out! 👉 Learn more & apply: escardio.org/Research/Res... #CardioSky

escardio.org

Scientific Exchange Grants

Your access to the latest cardiovascular news, science, tools and resources.

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Reposted by Dan Johnson

JMCC Plus @jmccplus.bsky.social · 07/11/2025

On your way to #AHA or just looking for some weekend reading? Check out the latest paper from Warren et al who uncovered region-specific metabolic and signalling changes in the endocardium vs epicardium in a mini-pig model of #HCM 🫀🫀 sciencedirect.com/science/arti... #CardioSky #AnimalModel

sciencedirect.com

Signaling pathway alterations in hearts of a porcine model harboring a β-myosin heavy chain (MYH7-R403Q) gene variant

The disease-causing myosin variant (MYH7-403Q) is linked to hypertrophic cardiomyopathy (HCM). We carried out a research study of signaling pathways i…

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Reposted by Dan Johnson

JMCC Plus @jmccplus.bsky.social · 03/11/2025

New work from Daoud et al. shows that removal of YAP/TAZ from vascular smooth muscle cells triggers inflammation and immune activation- indicating these factors as essential in vascular health.#vascularbiology sciencedirect.com/science/arti... #CardioSky

sciencedirect.com

YAP/TAZ deletion in vascular smooth muscle cells mirrors atherosclerosis-associated transcriptional programs

The transcriptional co-activators YAP (YAP1) and TAZ (WWTR1) are central regulators of vascular smooth muscle cell (VSMC) phenotype and vascular homeo…

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Reposted by Dan Johnson

JMCC Plus @jmccplus.bsky.social · 30/10/2025

We often treat #diabetes and #heart #disease separately — but they’re connected🫀. A recent study from Srinivas, Alluri et al. shows that removing CHOP in β-cells protects against both metabolic dysfunction and cardiac fibrosis in T2D mice. sciencedirect.com/science/arti... #CardioSky #NewPaper

sciencedirect.com

Deletion of CHOP in beta cell protects mice from cardiovascular complications in type 2 diabetes: evidence from a pre-clinical mouse model

Cardiovascular complications are the leading cause of morbidity and mortality in patients with type 2 diabetes (T2D), which is recognized as a major i…

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Reposted by Dan Johnson

JMCC Plus @jmccplus.bsky.social · 27/10/2025

🫀 New in JMCC Plus! Age, sex & vessel region shape vasomotor function in the descending thoracic #aorta — with #endothelial integrity & relaxation declining with age. Want to know more- check out Saemann et al.: sciencedirect.com/science/arti... #CardioSky @jmccardiology.bsky.social

sciencedirect.com

Age, sex, and vessel region affect the vasomotor function and gene expression signature of the aorta in mice

Vascular aging is associated with endothelial dysfunction, changes in vascular elasticity or stiffness, and the prevalence of cardiovascular diseases.…

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Reposted by Dan Johnson

JMCC Plus @jmccplus.bsky.social · 23/10/2025

New work from Nicole S. York and the group of Leigh Anne Swayne at the University of Victoria charts how #H9c2 heart cells change shape, signal, & express genes during differentiation—revealing both their promise & limits as #cardiomyocyte models. #CardioSky sciencedirect.com/science/arti...

sciencedirect.com

Quantification of morphological, functional, and biochemical features of H9c2 rat cardiomyoblast retinoic acid differentiation

Cell culture models enable advancement in our understanding of heart development and heart disease. The H9c2 rat ventricular cardiomyoblast cell line …

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Reposted by Dan Johnson

JMCC Plus @jmccplus.bsky.social · 17/10/2025

Ever wondered how #Calcium channels cluster in #iPSC derived #Cardiomyocytes? New work just published from Schwenzer et al. should put your mind at rest as they investigated just that! Check out the latest paper for more information www.sciencedirect.com/science/arti... #CardioSky

sciencedirect.com

Nanoscale architecture and dynamics of CaV1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy

The clustering of L-type calcium channels for functional regulation of intracellular calcium signaling remains poorly understood. Here we applied supe…

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Dan Johnson @danmjohnson.bsky.social · 08/10/2025

“Together, we innovate.” 🧬 @escardio.bsky.social is funding collaboration across borders If you’re an #ECR in #cellular #cardiac #electrophysiology, this is your chance to build connections & push your science forward. escardio.org/Research/Res... Deadline- 8 Dec 2025 #CardioSky #BasicScience

escardio.org

Scientific Exchange Grants

Your access to the latest cardiovascular news, science, tools and resources.

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Reposted by Dan Johnson

JMCC Plus @jmccplus.bsky.social · 03/10/2025

Looking for some weekend reading? 📜 New work from from the University of Ottawa Heart Institute, show how metabolic substrates regulate effects of Wnt/β-catenin signaling in #cardiomyocytes, specifically affecting regulation of #Connexin43 sciencedirect.com/science/arti...

sciencedirect.com

Wnt/β-catenin signaling regulates cardiac Cx43 in a metabolic substrate-dependent manner

Both Nav1.5 and Cx43 are critical for the fast electrical impulse conduction in the myocardium and their reductions create the arrhythmogenic substrat…

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Dan Johnson @danmjohnson.bsky.social · 29/06/2025

Less than 24 hours to go before the #EWGCCE meeting kicks off @escardio.bsky.social #HeartHouse in the South of France! Looking forward to a great scientific programme and meeting up with colleagues and friends over the next days! Safe travels all! #CardioSky

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Dan Johnson @danmjohnson.bsky.social · 30/05/2025

Really nice work just out in @jmccplus.bsky.social ! Congrats to the Authors #CardioSky

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Dan Johnson @danmjohnson.bsky.social · 28/05/2025

Title deadline of 2nd June for @escardio.bsky.social WG in #Cardiac Cellular #Electrophysiology meeting next month. Want to hear about the latest work in cellular cardiac electrophysiology-, you know what you need to do! #cardiosky esc365.escardio.org/event/1815

esc365.escardio.org

49th EWGCCE Meeting 2025 on ESC 365

Seminar on Cellular Electrophysiology by the WG on Cardiac Cellular Electrophysiology to improve your practice and prepare for your exams.

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Reposted by Dan Johnson

ilesla.bsky.social @ilesla.bsky.social · 19/05/2025

Considering a return to study in the life/environmental sciences at Masters/PhD level after time away? Working and wondering if full/part-time study is the next step for your career? Our RePOWER workshop on 13th June in Oxford/online will provide advice and support. iles.web.ox.ac.uk/repower-retu...

iles.web.ox.ac.uk

RePOWER: Returning to Postgraduate Study in the Life and Environmental Sciences

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Dan Johnson @danmjohnson.bsky.social · 19/05/2025

Interested in presenting your latest #CardiacElectrophysiology data but didnt have chance to submit an abstract to this years #EWGCCE? Still time to submit a title and register for this meeting happening in June/July esc365.escardio.org/event/1815 Hopefully see you there! #CardioSky

esc365.escardio.org

49th EWGCCE Meeting 2025 on ESC 365

Seminar on Cellular Electrophysiology by the WG on Cardiac Cellular Electrophysiology to improve your practice and prepare for your exams.

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Dan Johnson @danmjohnson.bsky.social · 09/05/2025

Some really nice work just out in @jmccplus.bsky.social Congrats to the Authors! #CardioSky

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Dan Johnson @danmjohnson.bsky.social · 21/03/2025

Really nice work just out... Interested in neuro-cardio interactions, have a read!

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Dan Johnson @danmjohnson.bsky.social · 05/03/2025

Deadline Extended until the 10th March for submission of abstracts for the WGCCE meeting this year happening in the south of France! Submit your abstract today at esc365.escardio.org/event/1815 This meeting is the perfect place to conduct some great conversations!! #CardioSky

esc365.escardio.org

49th EWGCCE Meeting 2025 on ESC 365

Seminar on Cellular Electrophysiology by the WG on Cardiac Cellular Electrophysiology to improve your practice and prepare for your exams.

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Dan Johnson @danmjohnson.bsky.social · 12/02/2025

This should be a very interesting webinar! Looking forward to seeing you there! #CardioSky

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Dan Johnson @danmjohnson.bsky.social · 30/01/2025

Fantastic news from @jmccplus.bsky.social 🥳🥳 Congrats to all involved.. Im currently hosting a #SpecialIssue on #Remodelling in #HFpEF! 🫀 Feel free to get in touch if you are interested in submitting!

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Dan Johnson @danmjohnson.bsky.social · 20/01/2025

Really nice research just out in @jmccplus.bsky.social looking at a novel biomarker for #CardiogenicShock! Congrats to the Authors!

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Dan Johnson @danmjohnson.bsky.social · 10/01/2025

Fantastic to be at the emeritus celebration of Karin Sipido in Leuven today! Great to see some old friends and colleagues! #CardioSky

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Dan Johnson @danmjohnson.bsky.social · 03/01/2025

A new paper just out in PLoS One looking at how a #HighFatDiet can influence #Cardiac #Electrophysiology and the role of NOX2. Congrats to the Authors and thanks to the Reviewers! #CardioSky journals.plos.org/plosone/arti...

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Dan Johnson @danmjohnson.bsky.social · 18/12/2024

Fantastic new work just out in @jmccplus.bsky.social ! Congrats to the Authors, and thanks to the Reviewers #CardioSky #MedSky

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Dan Johnson @danmjohnson.bsky.social · 06/12/2024

Very pleased to announce the launch of the new ILELSA PhD studentship scheme in collaboration with Open University, @ox.ac.uk and Oxford Brookes Interested in joining us on themes including Animal and Human Health or the Rules of Life? Get in touch! iles.web.ox.ac.uk @oxforddpag.bsky.social

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Dan Johnson @danmjohnson.bsky.social · 04/12/2024

Less than a week left to apply for #WGCCE scientific exchange grants! The perfect opportunity to go learn new skills in another European lab! More info can be found here escardio.org/Research/Res... #CardioSky @llew-cardio.bsky.social @cristinamolina.bsky.social

escardio.org

Scientific Exchange Grants

Your access to the latest cardiovascular news, science, tools and resources.

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Dan Johnson @danmjohnson.bsky.social · 28/11/2024

The amount of money in the swear jar may go up, but at least im exercising!

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Dan Johnson @danmjohnson.bsky.social · 26/11/2024

Great to see @jmccplus.bsky.social now over on Bluesky! Follow for all the latest news/articles published in this new open access upcoming journal from the ISHR! Interesting paper to open their account on immune checkpoint inhibitors and myocarditis! #CardioSky #MedSky

media.tenor.com

a sign that says welcome on it with feathers flying in the background

ALT: a sign that says welcome on it with feathers flying in the background

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Dan Johnson @danmjohnson.bsky.social · 22/11/2024

Great to have made so many connections on @bsky.app over the last weeks.. Interested in the research i do? See the following word cloud created with shiny.rcg.sfu.ca/u/rdmorin/sc... Happy weekend everyone!

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Dan Johnson @danmjohnson.bsky.social · 22/11/2024

Hi @richardbj.bsky.social .. Could you please add me to the #ionchannels starter pack that you have set up? All the best

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Reposted by Dan Johnson

Constantijn Franssen @cfranssen.bsky.social · 20/11/2024

How about starting here with a job vacancy? We're looking for a talented PhD candidate to contribute to our innovative research in #cardiooncology. 1/n

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