Looking for some weekend reading? 📜
New work from from the University of Ottawa Heart Institute, show how metabolic substrates regulate effects of Wnt/β-catenin signaling in #cardiomyocytes, specifically affecting regulation of #Connexin43
sciencedirect.com/science/arti...
sciencedirect.com
Wnt/β-catenin signaling regulates cardiac Cx43 in a metabolic substrate-dependent manner
Both Nav1.5 and Cx43 are critical for the fast electrical impulse conduction in the myocardium and their reductions create the arrhythmogenic substrat…