iiinova — where your digital self keeps evolving

Reposted by Dan Landry

ACOG @acog.org · 22/09/2025

ACOG reaffirms that acetaminophen is safe for managing pain and fever during pregnancy. No reputable studies support suggestions like those in HHS’s recent announcement linking acetaminophen use in pregnancy to autism; in fact, high-quality studies show no such risk. bit.ly/47Wxc59

2220011133

Reposted by Dan Landry

NEJM.org @nejm.org · 21/06/2025

In the latest video in our partnership with @glaucomflecken.bsky.social, the BALANCE trial comparing 7 days of antibiotic treatment with 14 days of treatment in patients with bloodstream infection is explained. Access the article for free: nej.md/DrG19

38731

Reposted by Dan Landry

ID Chief @ UMich @adamlauring.bsky.social · 21/06/2025

Gold “just make a decision”

031

Reposted by Dan Landry

Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 20/05/2025

What’s the optimal cefazolin dose for MSSA CNS infections? New PK/PD data says: it’s not just about higher doses—MIC matters. 2g q6h works only if MIC <=0.5 mg/L For MIC:1-2 mg/L, continuous infusion (10–12g/day) may be needed to hit PD targets #idsky journals.asm.org/doi/10.1128/...

4355

Dan Landry @danlandry.bsky.social · 07/02/2025

2025 has been..... interesting....so far

010

Reposted by Dan Landry

Angie Rasmussen @angierasmussen.bsky.social · 01/01/2025

So the kid in BC with H5N1 was very sick to the point of needing ECMO. While the majority of human cases have not been severe, this virus has the potential to be as bad as other H5N1s. At population scale, even infrequently, this is millions of people. www.nejm.org/doi/full/10....

nejm.org

Critical Illness in an Adolescent with Influenza A(H5N1) Virus Infection | NEJM

Influenza A(H5N1) viruses are an emerging zoonotic threat and have spread widely throughout birds in North America. Recently, influenza A(H5N1) infection led to serious illness in a teenager in Canada.

615649

Dan Landry @danlandry.bsky.social · 29/12/2024

I had heard the same, but don't know much other than that

000

Dan Landry @danlandry.bsky.social · 28/12/2024

Yeah I've heard that one too... although another person was saying they thought a submission was sent in to Health Canada almost a year ago. If that's true, not sure what the holdup is...

110

Reposted by Dan Landry

Josh Davis @gurujosh.bsky.social · 23/12/2024

It's that time of year again. Here are my top 10 ID papers of 2024 1. My opinion 2. Practice changing, paradigm-shifting or dogma challenging 3. Not COVID 4. Alphabetical order by first author 5. CoI for 4 and 5 (I am an author) Summary slide here, details in thread #IDSky #Top10IDpapers

1110236

Reposted by Dan Landry

Anthony Lau, PharmD BCPS @alaurx.bsky.social · 18/12/2024

"Disney princesses face serious real world health hazards. Surprisingly, however, despite these risks they seem to live happily ever after!" 👸 Another BMJ Christmas Special!👇 www.bmj.com/content/387/... #medsky #pharmsky #nursesky #GPsky #MedEd

bmj.com

12010

Reposted by Dan Landry

Jason Gallagher @jgpharmd.bsky.social · 18/12/2024

The great irony of this is that the incredible success of vaccinations allows for the skepticism of them. If these diseases were common and we saw vaccines preventing severe diseasen in vaccinated people and deaths in unvaccinated people, there wouldn’t be a question. 1/

2272

Reposted by Dan Landry

Angie Rasmussen @angierasmussen.bsky.social · 18/12/2024

This is a lie. And it’s an abhorrent lie because the goal of this lie is to prevent polio vaccination and kill even more people.

18521178

Dan Landry @danlandry.bsky.social · 16/12/2024

Yeah exactly. Our site has also integrated IVP cefazolin in our dialysis unit for post-HD doses (less chair time being wasted)

220

Reposted by Dan Landry

Bug Pharmacist // Tim Gauthier @idstewardship.bsky.social · 14/12/2024

📋👀 Did you miss any of these articles from 2024? 📲 www.idstewardship.com/year-review-... #IDsky with @absteward.bsky.social

13211

Dan Landry @danlandry.bsky.social · 15/12/2024

I'd say reduced nursing time is certainly a good thing, as the nursing staff here is already overburdened. Another area where IV-push is great for operational reasons would be for pre-op surgical prophylaxis, to ensure folks get it at the right time

110

Reposted by Dan Landry

Dr. Glaucomflecken @glaucomflecken.bsky.social · 12/12/2024

Health insurance industry PR is working overtime right now diverting blame to physicians for claim denials and rising costs. I feel compelled to remind everybody that Optum (UHC) is the largest employer of physicians in the US. We have never had less power in healthcare than we do right now.

6540821378

Reposted by Dan Landry

Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 11/12/2024

🔥🔥 NEW 🔥🔥 Year In Review: Top Infectious Diseases Articles From 2024 Our new post, a great collaboration with my friend 🌟 @idstewardship.bsky.social 1️⃣6️⃣⚡️🆔 RCTs 7️⃣Syst Reviews/Meta 3️⃣🌏Guidelines ✨️Wiki_Guidelines #idsky #EMIMCC #medsky #utisky EnJoy Share plz! www.idstewardship.com/year-review-...

idstewardship.com

Year In Review: Top Infectious Diseases Articles From 2024

In this article a selection of notable peer-reviewed publications from 2024 are provided. Article Selection by: Bassam Ghanem, Pharm.D., MS, BCPS Article Construction by: Timothy P. Gauthier, Pharm.D....

1012152

Reposted by Dan Landry

Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 10/12/2024

Pharmacodynamic studies indicate that anaerobic killing is optimized when the plasma AUC) to MIC ratio is ≥70:1; the probability of achieving this target with 1000mg/d of metronidazole is > 99% against B. fragilis that exhibit MICs < 2mg/L #idsky #medsky #EMIMCC

2114

Dan Landry @danlandry.bsky.social · 10/12/2024

My eyes immediately went to the 30° temps....and then realized it was in °F (and not °C) #CanadaProblems

010

Dan Landry @danlandry.bsky.social · 07/12/2024

When you're trying to decide between PO/IV in the vast majority of hemodynamically stable patients (tolerating oral intake), these are essentially the options you're weighing! #ID #IDmemes #AMS

052

Reposted by Dan Landry

Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 07/12/2024

Golden rules by @bradspellberg.bsky.social 1️⃣🌟There is nothing magical about IV antibiotics. 2️⃣🌟There's no magical infectious disease that requires IV antibiotic treatment. 3️⃣🌟There is NO minimum required IV lead-in duration IV "lead in" is a myth #idsky #medsky #EMIMCC

2366

Dan Landry @danlandry.bsky.social · 06/12/2024

Tmp-Smx dose seems a bit high, I'd echo others who said to drop the dose. I wouldn't automatically go with PJP doses. If source control is achieved (seems to be from what I understan), I don't see a reason to go avoid PO options. So Levo (or mino) would be other options IMHO

010

Reposted by Dan Landry

Dr. Glaucomflecken @glaucomflecken.bsky.social · 05/12/2024

One thing I didn’t expect in the wake of the CEO shooting is the sudden attention on health insurance policy. I have seen this video and the BCBS policy itself go viral on almost every platform. People are waking up. Real lasting change in healthcare is coming. youtube.com/shorts/vWA2a...

youtube.com

No More General Anesthesia

YouTube video by Dr. Glaucomflecken

702277526

Dan Landry @danlandry.bsky.social · 05/12/2024

The studies by @ericmacymd.bsky.social and colleagues on populations of millions of patients have been great at separating that aspect. They've shown it's safe to give cephalosporins to patients with penicillin allergy (irrespective of side chain similarities). 2/2

010

Dan Landry @danlandry.bsky.social · 05/12/2024

It depends on the interpretation of the question too. Pen "allergic" patients are more likely to be "allergic" to any other drug (irrespective of structure). But there isn't any evidence that there's a bigger risk increase for allergy with a cephalosporin compared to TMP/SMX. 1/2

110

Dan Landry @danlandry.bsky.social · 05/12/2024

We would give cefazolin even if it was an anaphylactic penicillin allergy. There's no good evidence to support cross reactivity.

160

Dan Landry @danlandry.bsky.social · 04/12/2024

7 days seems reasonable to me!

030

Dan Landry @danlandry.bsky.social · 04/12/2024

Meropenem deficiency maybe? 🤣

130

Dan Landry @danlandry.bsky.social · 04/12/2024

Restarting from scratch on here instead of trying to force a round peg into a square hole over on Twitter! #n00b

190