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Reposted by Dan Harki

RSC Medicinal Chemistry @rscmedchem.rsc.org · 07/05/2025

Take a look at recent work from Jared J. Anderson and @danharki.bsky.social on the identification of a novel allosteric binding site on the catalytic domain of NF-κB inducing kinase (NIK)🔥⬇ pubs.rsc.org/en/content/a... 📍 @umnmedchem.bsky.social #chemsky🧪

pubs.rsc.org

Identification of a novel allosteric binding site on the catalytic domain of NF-κB inducing kinase (NIK)

NF-κB inducing kinase (NIK) is the central regulatory component of noncanonical NF-κB signalling and has been implicated in a variety of cancers and immune disorders. While NIK has been pursued as a…

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