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Dan Harki

@danharki.bsky.social
115 followers 84 following 4 posts

Professor at the University Minnesota. Membership & International Relationships Chair, ACS MEDI. Medicinal Chemistry. Drug Development. Synthesis. Chemical Biology. LA Dodgers Fan.

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Dan Harki @danharki.bsky.social · 12/05/2025
Congratulations to Mackenzie and Laura! www.pharmacy.umn.edu/news/mackenz...
pharmacy.umn.edu
Mackenzie Wyllie and Laura Hirsch Awarded Doctoral Dissertation Fellowships
This prestigious award is bestowed upon the University's most outstanding PhD candidates for their accomplishments in highly significant and innovative research areas.
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Reposted by Dan Harki
RSC Medicinal Chemistry @rscmedchem.rsc.org · 07/05/2025
Take a look at recent work from Jared J. Anderson and @danharki.bsky.social on the identification of a novel allosteric binding site on the catalytic domain of NF-κB inducing kinase (NIK)🔥⬇ pubs.rsc.org/en/content/a... 📍 @umnmedchem.bsky.social #chemsky🧪
pubs.rsc.org
Identification of a novel allosteric binding site on the catalytic domain of NF-κB inducing kinase (NIK)
NF-κB inducing kinase (NIK) is the central regulatory component of noncanonical NF-κB signalling and has been implicated in a variety of cancers and immune disorders. While NIK has been pursued as a…
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Dan Harki @danharki.bsky.social · 27/04/2025
The #HarkiLab at the #MIKIW2025 meeting at the University of Kansas.
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Dan Harki @danharki.bsky.social · 19/04/2025
New work to characterize the ligandability of NIK with an electrophilic fragment. pubs.rsc.org/en/content/a...
pubs.rsc.org
Identification of a novel allosteric binding site on the catalytic domain of NF-κB inducing kinase (NIK)
NF-κB inducing kinase (NIK) is the central regulatory component of noncanonical NF-κB signalling and has been implicated in a variety of cancers and immune disorders. While NIK has been pursued as a t...
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Reposted by Dan Harki
C&EN (Chemical & Engineering News) @cenmag.bsky.social · 27/03/2025
Treating a deadly childhood cancer with a sideways approach: Degrading a critical scaffolding protein may help treat neuroblastoma. cen.acs.org/acs-news/acs... #chemsky🧪 #biosky
cen.acs.org
Treating a deadly childhood cancer with a sideways approach
Degrading a critical scaffolding protein may help treat neuroblastoma
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