pubmed.ncbi.nlm.nih.gov
Dendritic translation and neuroproteasome-mediated degradation of endogenous tau revealed by STARFISH - PubMed
In Alzheimer's disease, the protein tau is thought to redistribute from axons to the somatodendritic compartment and form fibrillar aggregates. Although tau aggregation is a hallmark of Alzheimer's disease, the dynamics of its synthesis and degradation are not well characterized. Given that nascent …