iiinova — where your digital self keeps evolving

Christophe Wirth

@chriswir.bsky.social

Reposted by Christophe Wirth

Claudine Kraft's Lab @kraftlabfr.bsky.social · 14/04/2026

🚨 Paper Alert! In this new work published in @jcellsci.bsky.social we shift our focus on MTFR1L and the feedback loop linking mitochondrial fission, mitophagy and apoptosis. MTFR1L emerges as a critical coordinator of the fission and autophagy machinery. 🔗Find the paper here: doi.org/10.1242/jcs....

23213

Christophe Wirth @chriswir.bsky.social · 19/01/2026

X-ray diffraction data were collected at @esrf.fr on various MX beamlines. Thanks to @dfg.de @uni-freiburg.de @uniklinik-fr.bsky.social @cibss.bsky.social for the funding

020

Christophe Wirth @chriswir.bsky.social · 16/01/2026

Happy to share our paper in the frame of the @sfb1453.bsky.social project that got published in @jmolbiol.bsky.social Tremendous work from @emymrikov.bsky.social and others, on how the scaffold protein PDZK1 interacts with the urate transporter URAT1. ⬇️ www.sciencedirect.com/science/arti...

sciencedirect.com

Molecular Determinants of Selective and High-affinity Binding of the Scaffold Protein PDZK1 to the Urate Transporter URAT1

The renal solute carrier URAT1 (SLC22A12) is essential for urate homeostasis, with loss-of-function linked to renal hypouricemia, nephrolithiasis and …

021