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Chemical Biology Resources

@chembl.bsky.social
70 followers 6 following 35 posts

The Chemical Biology Resources team at EMBL-EBI provides free resources supporting drug discovery and handling small molecules in biological databases.

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Chemical Biology Resources @chembl.bsky.social · 29/09/2026
An interesting use of ChEMBL, by friend of the group, Chris Swain.
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Chemical Biology Resources @chembl.bsky.social · 22/08/2026
We're still inviting applications from interested candidates for this postdoctoral fellowship. Get in touch directly if interested. #chemjobs #cheminformatics #bioinformarics
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Chemical Biology Resources @chembl.bsky.social · 10/08/2026
Interested in a 3-year Postdoctoral Fellowship developing our services, and working in collaboration with a major pharmaceutical company? Then checkout this blogpost, and get in touch asap: chembl.blogspot.com/2026/06/invi...
chembl.blogspot.com
Invite to apply for ARISE2 Postdoctoral Fellowship
The Chemical Biology Services team invites applications for a 3-year ARISE2 Postdoctoral Fellowship – a unique postdoctoral opportunity t...
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Chemical Biology Resources @chembl.bsky.social · 10/08/2026
Interested in a 3-year Postdoctoral Fellowship developing our services, and working in collaboration with a major pharmaceutical company? Then checkout this blogpost, and get in touch asap: chembl.blogspot.com/2026/06/invi...
chembl.blogspot.com
Invite to apply for ARISE2 Postdoctoral Fellowship
The Chemical Biology Services team invites applications for a 3-year ARISE2 Postdoctoral Fellowship – a unique postdoctoral opportunity t...
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EMBL-EBI Training @training.ebi.embl.org · 05/08/2026
Last few spaces remaining for our six-hour virtual workshop, 'Small molecules and their protein targets: interactions, function, and classification': www.ebi.ac.uk/training/eve... Register by 10 August 2026. @chembl.bsky.social | @pdbeurope.bsky.social | #UniProt 🧬 📊 🖥️
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Chemical Biology Resources @chembl.bsky.social · 06/07/2026
Ever wonder what a biological curator for ChEMBL does? We have two biological curators in the ChEMBL team, and over the course of this week, we'll look at typical activities one day at a time. We begin with Monday… chembl.blogspot.com/2026/07/a-we... #cheminformatics #chembl
chembl.blogspot.com
A week in the Life of a ChEMBL Biological Curator - Monday
This image was generated using AI. Ever wonder what a biological curator for ChEMBL does? Read on to find out what we were up to during th...
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Chemical Biology Resources @chembl.bsky.social · 15/06/2026
Last chance to apply to work on this exciting project, part of a larger collaboration with UCL. Closing date Jun 17th.
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Chemical Biology Resources @chembl.bsky.social · 03/06/2026
We have an opening for a Computational Biologist or Bioinformatician as part of the LIGMAP project with UCL, whose goal is to identify ligands for proteins of unknown function. Apply by June 17th to come work with us on the Genome Campus near Cambridge, UK. chembl.blogspot.com/2026/06/open...
chembl.blogspot.com
Open Position: Computational Biologist / Bioinformatician
We are looking for a highly motivated Computational Biologist / Bioinformatician (*) to join the Chemical Biology Resources team at the Euro...
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Chemical Biology Resources @chembl.bsky.social · 29/05/2026
chembl.blogspot.com/2026/05/chem...
chembl.blogspot.com
ChEMBL 37 is here: bigger, cleaner, and smarter about protein degradation
ChEMBL 37 arrives with nearly three million compounds, a new modality field for capturing targeted protein degraders, and a wave of data qua...
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EMBL-EBI @ebi.embl.org · 18/05/2026
What is the value of open data for the life sciences? 📈 New report by Frontier Economics shows that EMBL-EBI data resources save users an average of 11 hours/week/person, leading to £11.8bn/year in research productivity gains. s.embl.org/EMBL-EBI-202... #opendata
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Chemical Biology Resources @chembl.bsky.social · 21/05/2026
We have been working on curating data on new modalities, especially in the context of targeted protein degraders. This is very timely with the recent approval of the first PROTAC for therapeutic use, Vepdegestrant. Read more about what's coming in ChEMBL 37: chembl.blogspot.com/2026/05/the-...
chembl.blogspot.com
The first PROTAC has been approved: can we find it in ChEMBL?
ChEMBL extracts data from the core medicinal chemistry literature and therefore reflects ongoing developments in drug discovery. ...
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Chemical Biology Resources @chembl.bsky.social · 13/05/2026
Last chance to sign up to attend the our UGM. See you there? chembl.blogspot.com/2026/05/chem...
chembl.blogspot.com
ChEMBL UGM: Registration closes on 18th May
The full programme for the  ChEMBL UGM (June 10-11) is now available on our website. If you are interested in registering, you need to be q...
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Chemical Biology Resources @chembl.bsky.social · 11/05/2026
In advance of the ChEMBL/SureChEMBL UGM, we are running a survey to solicit feedback on our user interfaces, data offerings, and indeed more broadly on our future direction. Your response will be much appreciated as it tells us where to focus our resources. chembl.blogspot.com/2026/05/help...
chembl.blogspot.com
Help Shape the Future of ChEMBL: Take Our User Survey Now!
Dear ChEMBL and SureChEMBL Community, As you know we are dedicated to keeping ChEMBL and SureChEMBL world-class resources for the sc...
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Chemical Biology Resources @chembl.bsky.social · 03/03/2026
The deadline for in-person registration for the upcoming ChEMBL UGM is 18th March so please register soon. It would be great to see you there. #chembl #cheminformatics #chemsky chembl.blogspot.com/2026/03/seco...
chembl.blogspot.com
Second announcement of 2nd ChEMBL User Group Meeting
This is a reminder that the 2nd ChEMBL User Group Meeting will take place on June 10-11 on the Wellcome Genome Campus, Hinxton, near Cambri...
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macinchem.bsky.social @macinchem.bsky.social · 27/01/2026
Interesting post from the ChEMBL team. macinchem.org/2026/01/27/s...
macinchem.org
Supporting LIGAND-AI’s search for ligands for understudied targets – Macs in Chemistry
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Chemical Biology Resources @chembl.bsky.social · 14/01/2026
We've been curating the Target Protein Degradation (TPD) data in ChEMBL. Read more at chembl.blogspot.com/2026/01/expl...
chembl.blogspot.com
Exploring Targeted Protein Degradation Data in ChEMBL
Drug modalities continue to evolve and the capture of data from recent literature ensures that ChEMBL remains up-to-date with recent dev...
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Chemical Biology Resources @chembl.bsky.social · 14/01/2026
Registration is now open at www.ebi.ac.uk/about/events...
ebi.ac.uk
2nd ChEMBL User Group Meeting  – EMBL-EBI Events
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Chemical Biology Resources @chembl.bsky.social · 08/01/2026
A blogpost on changes to ChEMBL data deposition: chembl.blogspot.com/2026/01/chan... ...and not unrelated, a recent talk I gave on why data curation is needed and what it involves: github.com/chembl/prese...
chembl.blogspot.com
Changes to ChEMBL Data Deposition
Over the years, ChEMBL has accepted 336 datasets deposited by the community. In fact, these data now comprise around 50% of the bioactivity ...
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Chemical Biology Resources @chembl.bsky.social · 05/01/2026
Last chance (closing dates Jan 11) to apply for open positions in the team: www.ebi.ac.uk/about/teams/... 1. Technical Lead for the team - could be someone with either a scientific or computing background. 2. NLP Data Scientist/Scientific Data Engineer, to develop a drug side effect resource
ebi.ac.uk
Joining the group – Chemical Biology Services
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Chemical Biology Resources @chembl.bsky.social · 17/12/2025
The date for the ChEMBL UGM has been fixed for June 10-11 2026. The website is up at www.ebi.ac.uk/about/events... and registration opens in January. See you next year!
ebi.ac.uk
2nd ChEMBL User Group Meeting  – EMBL-EBI Events
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Open Targets @opentargets.org · 11/12/2025
NEW: NLP data scientists/scientific data engineers at @ebi.embl.org Develop a comprehensive open source side effect resource and standardised AI/ML training sets to improve early identification of safety liabilities Apply by 11 January embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
embl.wd103.myworkdayjobs.com
NLP Data Scientist/Scientific Data Engineer
About the team/job Safety and toxicology concerns remain one of the most persistent challenges in drug discovery. This is an exciting opportunity to join a multi-disciplinary team on a project to deve...
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Michael Kuhn @biocs.bsky.social · 11/12/2025
Text-mining tools have progressed a lot in the last two decades, and I'm excited to see what can be done now. More info chembl.blogspot.com/2025/12/new-... Apply here: embl.wd103.myworkdayjobs.com/EMBL/job/Hin... The position is at @ebi.embl.org #ScienceJobs #AcademicSky #ChemSky #BioSky [3/3]
chembl.blogspot.com
New position: NLP Data Scientist/Scientific Data Engineer
As part of a funded collaboration with Open Targets, there are two open positions as part of a team to develop a drug side effect resource:...
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Michael Kuhn @biocs.bsky.social · 11/12/2025
...but life intervened and funding changed, so SIDER sideeffects.embl.de is unfortunately gathering dust since its last update in 2015. But there's good news: @chembl.bsky.social and @opentargets.org are starting a new effort to mine the available data and produce a high-quality databases! [2/3]
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Chemical Biology Resources @chembl.bsky.social · 03/12/2025
We are looking for a new Technical Lead for our group. This is an exciting opportunity for someone either from a scientific or informatics background to play a key role in our team which has a huge impact on the scientific communities that we serve: chembl.blogspot.com/2025/12/open...
chembl.blogspot.com
Open Position: Technical Lead Chemical Biology Services
We are looking for a new Technical Lead to lead the technical maintenance and development of our group's services . This is an exciting opp...
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Chemical Biology Resources @chembl.bsky.social · 28/11/2025
The ChEBI 2.0 paper has just been published by Nucleic Acids Research. #chebi #ontology academic.oup.com/nar/advance-...
academic.oup.com
ChEBI: re-engineered for a sustainable future
Abstract. Chemical Entities of Biological Interest (ChEBI) is a high-quality, manually curated, and open-access database and ontology of chemical entities
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Chemical Biology Resources @chembl.bsky.social · 23/09/2025
ChEMBL 36 is out! chembl.blogspot.com/2025/09/chem...
chembl.blogspot.com
ChEMBL 36 is out!
📊 Database Scale 🆕 New Data Sources Src_ID 72 – Chemical Probe data from Scientific Literature NLP and manual extraction from probe-r...
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Chemical Biology Resources @chembl.bsky.social · 18/09/2025
We've just released a webinar that provides background on the #chembl database alongside worked examples highlighting some common scenarios in drug discovery initiatives. chembl.blogspot.com/2025/09/make...
chembl.blogspot.com
Make the most of the ChEMBL interface with our newest webinar!
Before starting a new drug discovery project, it’s useful to compile existing data on compounds and targets of interest. Open access bioacti...
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Chemical Biology Resources @chembl.bsky.social · 15/09/2025
We have gone back in time and generated SQLite files for all releases of #ChEMBL from version 1 onwards making it easier to carry out analyses across ChEMBL versions. chembl.blogspot.com/2025/09/sqli...
chembl.blogspot.com
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Chemical Biology Resources @chembl.bsky.social · 21/08/2025
Last chance to apply for this pivotal role, taking our services to the next level. Get in touch by end of Aug if interested...
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Chemical Biology Resources @chembl.bsky.social · 20/08/2025
Who would like to see 3D structures on ChEMBL? (*my hand shoots up*)
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Chemical Biology Resources @chembl.bsky.social · 08/08/2025
In support of @egonw.mastodon.social.ap.brid.gy 's 'One Million IUPAC Names' project, we have just released more than 4 million IUPAC names text-mined from patents. Read more at: chembl.blogspot.com/2025/08/unle...
chembl.blogspot.com
Unleashing 4 million IUPAC names into the wild
In support of Egon Willighagen's ' One Million IUPAC Names ' project, we have just released more than 4 million IUPAC names text-mined from...
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Chemical Biology Resources @chembl.bsky.social · 21/07/2025
A second post about the redevelopment of ChEBI, this time focussing on changes to the data products. chembl.blogspot.com/2025/07/cheb...
chembl.blogspot.com
ChEBI 2.0 Data Products
Image generated using DALLE-3 Introduction Dear ChEBI users, If you have visited the ChEBI website recently, you have been able to intuit t...
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Chemical Biology Resources @chembl.bsky.social · 14/07/2025
We are inviting applications for a 3-year ARISE2 Postdoctoral Fellowship with the team. Read more on our blog at: chembl.blogspot.com/2025/07/invi...
chembl.blogspot.com
Invite to apply for ARISE2 Postdoctoral Fellowship
The Chemical Biology Services team invites applications for a 3-year ARISE2 Postdoctoral Fellowship – a unique postdoctoral opportunity th...
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Reposted by Chemical Biology Resources
EMBL-EBI @ebi.embl.org · 14/07/2025
🚨Our user survey is closing on 24 July. Only a few days left to share your views. Please take 10 minutes to help us demonstrate the value of the data resources we manage with our collaborators. Complete survey 👇 www.surveymonkey.com/r/QGFMBH8?ch... 🖥️🧬 #FAIRdata
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Chemical Biology Resources @chembl.bsky.social · 11/07/2025
ChEBI is undergoing a redevelopment. Read more on our blog at: chembl.blogspot.com/2025/07/rede...
chembl.blogspot.com
The Redevelopment of ChEBI
We are delighted to announce that ChEBI’s beta version is now out and can be accessed at:  https://www.ebi.ac.uk/chebi/beta/ As many of you ...
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Chemical Biology Resources @chembl.bsky.social · 11/07/2025
We would very much appreciate people taking the time to fill our impact survey. This helps makes the case for support for our resources. Survey closes on July 16th.
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Tobi Alegbe @tobioinformatics.bsky.social · 08/07/2025
Last but by no means least, we chose to take a reversed approach and check which of our colocalised IBD genes were ALREADY drug targets for non-IBD diseases. With a little help from @chembl.bsky.social and @opentargets.org , we noticed two particularly interesting cases: PSEN2 and NDUFAF1…
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Chemical Biology Resources @chembl.bsky.social · 25/06/2025
The ChEMBL-og: Support ChEMBL - EMBL-EBI user survey! chembl.blogspot.com/2025/06/supp...
chembl.blogspot.com
Support ChEMBL - EMBL-EBI user survey!
If our data resources have ever been of use to you, here’s your chance to give back! EMBL-EBI’s impact survey aims to understand the usage,...
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Chemical Biology Resources @chembl.bsky.social · 26/05/2025
Just one week left to apply for this position in our team, as frontend developer: embl.wd103.myworkdayjobs.com/EMBL/job/Hin...
embl.wd103.myworkdayjobs.com
Frontend Developer
We are looking for a talented frontend developer to join the Chemical Biology team at the European Bioinformatics Institute (EMBL-EBI) located on the Wellcome Genome Campus near Cambridge in the UK. T...
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Reposted by Chemical Biology Resources
EMBL-EBI @ebi.embl.org · 21/05/2025
As chemical data grows, turning names into machine-readable structures is key for discovery, automation, and data integration. OPSIN – now hosted at EMBL-EBI – helps solve this by converting IUPAC names into chemical structures and other machine-readable formats. www.ebi.ac.uk/about/news/u...
ebi.ac.uk
OPSIN chemical name-to-structure tool moves to EMBL-EBI
The Open Parser for Systematic IUPAC Nomenclature (OPSIN) allows users to convert chemical names into structures and machine-readable formats.
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Chemical Biology Resources @chembl.bsky.social · 17/05/2025
In collaboration with Dr Daniel Lowe, we are delighted to announce that the new home of the OPSIN web service is at EMBL-EBI. This well-known service converts systematic IUPAC names to structure. Read more on our post: chembl.blogspot.com/2025/05/opsi...
chembl.blogspot.com
OPSIN's new home is at EMBL-EBI
We are delighted to announce that the OPSIN web app has become a member of the Chemical Biology Services here at EMBL-EBI and can be acces...
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Chemical Biology Resources @chembl.bsky.social · 07/05/2025
Major changes are on the way to SureChEMBL...
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EMBL-EBI @ebi.embl.org · 30/04/2025
Welcome, Noel O’Boyle! Joining as EMBL-EBI’s new Chemical Resources Team Leader, Noel brings with him a background in chemistry, programming, & data-driven drug discovery 💊 Find out more: www.ebi.ac.uk/about/news/p...
ebi.ac.uk
Welcome: Noel O’Boyle
EMBL-EBI’s new Chemical Biology Resources Team Leader aims to encourage community engagement and explore AI-driven approaches.
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Chemical Biology Resources @chembl.bsky.social · 14/01/2025
The ChEMBL web interface now also displays cross links to Alpha Fold Database. Here is an example: www.ebi.ac.uk/chembl/explo...
ebi.ac.uk
Target: Receptor tyrosine-protein kinase erbB-2 (CHEMBL2311234)
Report card for Target Receptor tyrosine-protein kinase erbB-2 (CHEMBL2311234). Mus musculus, SINGLE PROTEIN, 2.7.10.1, CD_antigen=CD340, Erbb2, Kiaa3023, Neu, ...
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Chemical Biology Resources @chembl.bsky.social · 09/01/2025
The ChEMBL group is now posting on Bluesky!
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