iiinova — where your digital self keeps evolving

Marika Charalambous

@charalambouslab.bsky.social

157 followers 175 following 7 posts

Group leader at King's College London & the Francis Crick Institute. We study developmental programming, maternal-fetal interactions and the wonder that is pregnancy metabolism.

Posts Replies Media

Reposted by Marika Charalambous

Geula Hanin @geula.bsky.social · 09/02/2026

🎉 After a very long one (appropriately…), I’m excited to share work revealing an unexpected role for the epigenetic regulator ZFP57 - linking development, lactation, milk composition and lifelong health. Check it out: www.nature.com/articles/s41... #MammaryGlandBiology #DOHaD

nature.com

ZFP57 is a regulator of postnatal growth and life-long health - Nature Communications

Lactation is essential, but its genetic and epigenetic regulation is poorly understood. Here, Hanin et al. show that ZFP57 has an imprinting-independent role in controlling postnatal nutritional suppo...

4177

Marika Charalambous @charalambouslab.bsky.social · 02/02/2026

Thanks @smamante.bsky.social and @brancolab.bsky.social for including us in this cool project!

020

Marika Charalambous @charalambouslab.bsky.social · 15/01/2026

How do the mesodermally-derived cells contribute to placental function? In our new preprint we show that in the placental mesoderm the imprinted gene Dlk1 controls sensitivity to extrinsic signals via FOXO1. This regulates endothelial branching and hormone production.

100

Reposted by Marika Charalambous

Barral Lab @barrallab.bsky.social · 24/11/2024

Our first 🦋 post! Very happy to share our latest paper just out in Cell Reports, exploring the crosstalk between immune and epithelial cells in the gut. Check it out! @vivianlilab.bsky.social @kingscollegelondon.bsky.social www.cell.com/cell-reports...

cell.com

IFN-γ-dependent regulation of intestinal epithelial homeostasis by NKT cells

The crosstalk between immune and epithelial cells is vital to maintain intestinal homeostasis. Lebrusant-Fernandez et al. identify NKT cells in the small intestine as key regulators of epithelial biol...

520457