Covalent inhibitors and chemical probes targeting ligandable cysteine residues have emerged as powerful tools for drug discovery and proteomics. In this study, we introduce vinyl phosphonamidates (VPA...

Most cancer driving proteins remain undruggable due to the absence of ligandable pockets and their reliance on intrinsically disordered or protein-DNA/protein-protein interactions. Transcription facto...

Empowering Curious Researchers at the Vienna BioCenter PhD Program Are you a curious and motivated student looking to launch a successful scientific career? Look no further than the Vienna BioCenter P...

Our understanding of how post-translational modification—protein phosphorylation—impacts the complexity of eukaryotic signalling pathways is continuously expanding. Now, protein oligophosphorylation h...

It's been another exciting week where I feel compelled to write about the practice of university-based research in the US.  I've written ab...

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