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Cameron Mackereth

@cdmackereth.bsky.social
1.2K followers 1.1K following 6 posts

Scientist (🇨🇦) lucky to have a great group of researchers (🇨🇵) using big magnets for atomic-level insight on proteins & RNA, IDPs and DNA structures. INSERM scientist (French National Institute of Health and Medical Research) located at Univ. Bordeaux.

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Cameron Mackereth @cdmackereth.bsky.social · 03/12/2025
Our structure determination of a dopamine-binding DNA aptamer yielded surprising results. The structure had only 2 Watson-Crick base pairs, but lots of base pairs normally only seen in RNA folds. Check out our crazy DNA structure in the recent bioRxiv preprint, along with other binding details.
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Reposted by Cameron Mackereth
bioRxiv Biophysics @biorxiv-biophys.bsky.social · 19/04/2025
Functional relevance of CASP16 nucleic acid predictions as evaluated by structure providers www.biorxiv.org/content/10.1101/202…
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Cameron Mackereth @cdmackereth.bsky.social · 21/02/2025
Welcome to the new Bluesky account for the Bordeaux RNA Club @rnabordeaux.bsky.social We will soon be announcing details for the next symposium to be held 17-18 June.
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Reposted by Cameron Mackereth
Andy Fraser @andyfraser.bsky.social · 15/02/2025
We are looking to hire: 1. Skilled molecular biologist, specific expertise in SELEX or aptamers 2. Computational biologist wanting to take deep seq training data to crack the aptamer-target prediction problem My DMs are open - it is to drive this project forwards: www.nature.com/articles/s41...
nature.com
Quantifying metabolites using structure-switching aptamers coupled to DNA sequencing - Nature Biotechnology
Metabolites can be quantified using a combination of aptamers and DNA barcodes.
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Reposted by Cameron Mackereth
Irene Beusch @pauletteoctopus.bsky.social · 29/01/2025
Now official: We have another opening for a fully funded #PhDposition in the Beusch lab (www.beuschlab.org) at @uniwuerzburg.bsky.social! More details here: tinyurl.com/947xcw85 If you or someone you know is curious about #splicing please apply or contact me for more information! #RNAsky #RNAbiology
tinyurl.com
PhD-Beusch_202501_final.pdf
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Reposted by Cameron Mackereth
Eva Kowalinski @kowaeva.bsky.social · 21/01/2025
Architecture and RNA binding properties of the trypanosome nuclear cap-binding complex - key complex in the parasite’s RNA metabolism. Final peer-reviewed version is public! #RNAsky #trypsky www.nature.com/articles/s41...
nature.com
Structural basis of Spliced Leader RNA recognition by the Trypanosoma brucei cap-binding complex - Nature Communications
Bernhard et al. reveal the architecture of the tetrameric Trypanosoma brucei nuclear cap-binding complex. Using cryo-electron microscopy and biochemical assays, the researchers characterize its bindin...
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Reposted by Cameron Mackereth
Katja Petzold @katjapetzold.bsky.social · 10/12/2024
My NMR center is looking for a new staff scientist. It’s an amazing work environment at Uppsala University, Sweden. Come join us! www.uu.se/en/about-uu/...
uu.se
NMR research engineer - Uppsala University
NMR research engineer , Disciplinary Domain of Science and Technology, Faculty of Chemistry, Department of Chemistry - BMC, Uppsala University
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Cameron Mackereth @cdmackereth.bsky.social · 26/06/2024
It's been great working with the groups of @mazna.bsky.social and Davide Mercadante on this project. And already looking forward to the next experiments on eIF4B
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Cameron Mackereth @cdmackereth.bsky.social · 21/01/2024
First night at the yearly conference in the Swiss Alps after a lively poster session. The scenery is as pretty as always, and the snow this year looks great!
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Reposted by Cameron Mackereth
Juan Reguera @juanrv.bsky.social · 11/01/2024
A Post Doctoral position is open in my team @AFMBLab . We are looking for motivated researchers to help us understanding viral replication mechanisms in membranes by emerging RNA viruses. See the call in here => www.afmb.univ-mrs.fr/offre-de-con...
afmb.univ-mrs.fr
Offre de contrat Postdoctoral dans l’équipe ViMaC – AFMB
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Reposted by Cameron Mackereth
Jessica Andreani @jessicaandreani.bsky.social · 18/01/2024
Happy to share our research on using AlphaFold2 to predict how peptides from disordered regions bind proteins, just published in NatureComms rdcu.be/dwlLa Work done with Hélène Bret and Raphael Guerois and for the revised version with great contributions from @diegozea.bsky.social and Jinmei Gao. 🧬🧶
rdcu.be
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Reposted by Cameron Mackereth
Protein Data Bank in Europe (PDBe) @pdbeurope.bsky.social · 12/01/2024
Interested in small molecules 🧪 ⚗️ & 3D macromolecular structures? 'Accessing Enhanced Small Molecule Information in the Protein Data Bank in Europe' by @preeti_cy (Winter 2023 @RSC_CICAG Newsletter) ⬇️ Quick read ⬇️ www.rsccicag.org/newsletters....
Chemical structures in 3 different sizes of spheres. Each sphere has a different label: 41393 CCDs, 1115 PRDs, 2745 CLCs.
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Reposted by Cameron Mackereth
Protein Data Bank in Europe (PDBe) @pdbeurope.bsky.social · 02/01/2024
We’re delighted to have joined BlueSky to engage with the scientific community about macromolecular structures and related data. Follow us for updates on PDB and #AlphaFold DB databases, more info on our resources such as #PDBeKB, and for lots of beautiful structure images!
Structure image in background with PDBe logo in green and red at bottom right corner and text in a circle in the centre that reads 'PDBe is a founding member of the wwPDB consortium' with a green banner with white text that reads 'wwPDB'Structure image in background with PDBe-KB logo in green and red at bottom right corner and text in a circle in the centre that reads 'PDBe-KB is a consortium providing structural and functional annotation data' with a green banner with white text that reads 'PDBe-KB'Structure image in background with a circle in the centre that reads 'AlphaFoldDB is a collaboration between EMBL-EBI and Google DeepMind' with a blue banner with white text that reads 'AlphaFoldDB'Structure image in background with 3D-Beacons lighthouse design logo in green, red and grey at bottom right corner and text in a circle in the centre that reads 'The 3D-Beacons consortium provides a single access point for macromolecular structure data' with a green banner with white text that reads '3D-Beacons'
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