López and colleagues review recent evidence of RNA virus persistence and the associated consequences in terms of post-acute sequelae or chronic inflammatory syndromes.

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DURHAM, N.C. – The Burroughs Wellcome Fund is pleased to announce the recipients of the 2026 Investigators in the Pathogenesis of Infectious Disease (PATH) awards, recognizing assistant…

Author summary Viruses often produce non-standard viral genomes during replication. One important class of these molecules, called copy-back viral genomes (cbVGs), is known to strongly stimulate antiv...

Copy-back viral genomes (cbVGs) are generated during infection when the polymerase drops off from the template and reattaches to the nascent strand, and they are major drivers of antiviral immunity. H...

Most viruses of the order Mononegavirales have been demonstrated to naturally generate copyback viral genomes. These genomes are critical determinants of infection outcomes; they interfere with standa...

In a recent issue of Molecular Cell, Genoyer et al. show that during West Nile virus infection, escaped, cytoplasmic, anti-genomic negative-sense viral RNA triggers an antiviral response via RIG-I activation. Flaviviruses typically hide −vRNA in replication compartments to avoid detection, but some −vRNA leaks, possibly aided by viral capsid proteins.

This study shows that non-standard viral genomes of the "copy-back" type (cbVGs) trigger translation inhibition and stress granule formation during virus infection, independent of, and without affecti...

Columbia bent over backward to appease right-wing, pro-Israel attacks on Gaza protesters — and Trump still cut the school’s federal funding.

The AAUP defends the right to free speech and peaceful protest on college and university campuses, a time-honored tradition protected by the First Amendment of the United States Constitution. Donald T...

Earlier this month, the National Institutes of Health issued supplemental guidance indicating it would immediately impose a 15% cap on indirect costs for research grants, an unprecedented and abrup…

While some NIH study sections will resume, advisory council meetings, which make final funding decisions, seem to still be held up.

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ICYMI: Murray Blasts Trump and Musk Decimating HHS, Risking Americans’ Health and Livelihoods Washington, D.C. — U.S. Senator Patty Murray (D-WA), Vice Chair of the Senate Appropriations Committee and...

Author summary Paramyxovirus entry, the first step in establishing an infection, involves two key processes: attachment and virus-cell fusion. Paramyxoviruses use their attachment protein to bind to s...

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The discipline of microbiology is extremely broad as it encompasses the study of microscopic organisms and entities. The field of virology is a specialized area of study within the field of microbiology. Due to the complexity of virology as a field, herein we describe the development of curriculum guidelines and associated example learning objectives to help educators teach virology.

Viral RNA and protein are found to persist in infected lungs and contribute to post-acute pathology in Sendai virus infection.

In Feb., the American Academy of Microbiology elected 65 new fellows to the Class of 2024.